Intercalary reconstruction following resection of diaphyseal bone tumors: A systematic review

2021 ◽  
Author(s):  
Costantino Errani ◽  
Shinji Tsukamoto ◽  
Nusaibah Almunhaisen ◽  
Andreas Mavrogenis ◽  
Davide Donati
Keyword(s):  
Systematic Review ◽  
Bone Tumors ◽  
Diaphyseal Bone

Percutaneous microwave ablation of bone tumors: a systematic review

2020 ◽  
Author(s):  
Roberto Luigi Cazzato ◽  
Gianluca de Rubeis ◽  
Pierre de Marini ◽  
Danoob Dalili ◽  
Guillaume Koch ◽  
...  
Keyword(s):  
Systematic Review ◽  
Microwave Ablation ◽  
Bone Tumors ◽  
Percutaneous Microwave Ablation

scholarly journals Outcome of segmental prosthesis reconstruction for diaphyseal bone tumors: a multi-center retrospective study

BMC Cancer ◽  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Kai Zheng ◽  
Xiu-chun Yu ◽  
Yong-cheng Hu ◽  
Zeng-wu Shao ◽  
Ming Xu ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Bone Tumors ◽  
Diaphyseal Bone

scholarly journals Ablation of painful metastatic bone tumors: A systematic review

2008 ◽  
Vol 6 ◽  
pp. S47-S52 ◽  
Author(s):  
Gianpaolo Carrafiello ◽  
Domenico Laganà ◽  
Carlo Pellegrino ◽  
Monica Mangini ◽  
Federico Fontana ◽  
...  
Keyword(s):  
Systematic Review ◽  
Bone Tumors

scholarly journals Surgical options and reconstruction strategies for primary bone tumors of distal tibia: A systematic review of complications and functional outcome

2019 ◽  
Vol 14 ◽  
pp. 100209 ◽  
Author(s):  
Zhiqing Zhao ◽  
Taiqiang Yan ◽  
Wei Guo ◽  
Rongli Yang ◽  
Xiaodong Tang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Functional Outcome ◽  
Bone Tumors ◽  
Distal Tibia ◽  
Primary Bone Tumors ◽  
Surgical Options ◽  
Primary Bone

scholarly journals Denosumab for effective tumor size reduction in patients with giant cell tumors of the bone: a systematic review and meta-analysis

2019 ◽  
Author(s):  
Josef Yayan
Keyword(s):  
Systematic Review ◽  
Giant Cell ◽  
Phase Ii ◽  
Tumor Size ◽  
Bone Tumors ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Open Label ◽  
Phase Ii Studies ◽  
Open Label Phase

Abstract Background Denosumab is a human monoclonal antibody that is used in the successful treatment of giant cell bone tumors. These tumors are rare and, in principle, benign, but they are highly aggressive, locally advanced, and osteolytic bone tumors that can metastasize to the lungs. Denosumab is an effective treatment when these tumors cannot be surgically removed or when surgical resection is likely to lead to severe morbidity (e.g., loss of limbs or joints). The aim of this systematic review and meta-analysis was to investigate the patients with giant cell bone tumors who experienced tumor progression during treatment with denosumab and to compare them with patients who experienced reduction of their giant cell bone tumors during treatment with denosumab. Methods The Embase, Cochrane Library, and MEDLINE/PubMed databases were searched until February 28, 2018 for trials reporting the efficacy and safety of denosumab in patients with giant cell bone tumors. Results Thirty-three studies were reviewed, involving a total of 350 patients who had giant cell bone tumors and were treated with denosumab. Of the 33 studies, 67% of the patients were from open-label phase II studies, 27% from case series, and 6% from case reports. The response rate for denosumab as a treatment for giant cell bone tumors was 95.3%, with statistical significance (P < 0.0001). Osteonecrosis of the jaw was statistically the most common adverse event for denosumab treatment in open-label phase II studies (P < 0.0001). No treatment-related deaths occurred in the reviewed studies. Conclusion Cumulative evidence supports the addition of surgery to optimal medical therapy with denosumab to reduce tumor size, clinical symptoms, and mortality among patients with giant cell bone tumors.

The effects of low-ratio n-6/n-3 PUFA on biomarkers of inflammation: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Yali Wei ◽  
Yan Meng ◽  
Na Li ◽  
Qian Wang ◽  
Liyong Chen
Keyword(s):  
Systematic Review ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acid ◽  
Meta Analysis ◽  
Chain Polyunsaturated Fatty Acid ◽  
Inflammation Markers ◽  
Pufa Supplementation ◽  
Long Chain

The purpose of the systematic review and meta-analysis was to determine if low-ratio n-6/n-3 long-chain polyunsaturated fatty acid (PUFA) supplementation affects serum inflammation markers based on current studies.

Parent Education in Studies With Nonverbal and Minimally Verbal Participants With Autism Spectrum Disorder: A Systematic Review

2020 ◽  
Vol 29 (2) ◽  
pp. 890-902
Author(s):  
Lynn Kern Koegel ◽  
Katherine M. Bryan ◽  
Pumpki Lei Su ◽  
Mohini Vaidya ◽  
Stephen Camarata
Keyword(s):  
Systematic Review ◽  
Autism Spectrum Disorder ◽  
Parent Education ◽  
Autism Spectrum ◽  
Verbal Communication ◽  
Fidelity Of Implementation ◽  
Spectrum Disorder ◽  
Education Programs ◽  
Minimally Verbal ◽  
Parent Education Programs

Purpose The purpose of this systematic review was to identify parent education procedures implemented in intervention studies focused on expressive verbal communication for nonverbal (NV) or minimally verbal (MV) children with autism spectrum disorder (ASD). Parent education has been shown to be an essential component in the habilitation of individuals with ASD. Parents of individuals with ASD who are NV or MV may particularly benefit from parent education in order to provide opportunities for communication and to support their children across the life span. Method ProQuest databases were searched between the years of 1960 and 2018 to identify articles that targeted verbal communication in MV and NV individuals with ASD. A total of 1,231 were evaluated to assess whether parent education was implemented. We found 36 studies that included a parent education component. These were reviewed with regard to (a) the number of participants and participants' ages, (b) the parent education program provided, (c) the format of the parent education, (d) the duration of the parent education, (e) the measurement of parent education, and (f) the parent fidelity of implementation scores. Results The results of this analysis showed that very few studies have included a parent education component, descriptions of the parent education programs are unclear in most studies, and few studies have scored the parents' implementation of the intervention. Conclusions Currently, there is great variability in parent education programs in regard to participant age, hours provided, fidelity of implementation, format of parent education, and type of treatment used. Suggestions are made to provide both a more comprehensive description and consistent measurement of parent education programs.

Characteristics of the Frequency-Following Response to Speech in Neonates and Potential Applicability in Clinical Practice: A Systematic Review

2020 ◽  
Vol 63 (5) ◽  
pp. 1618-1635
Author(s):  
Céline Richard ◽  
Mary Lauren Neel ◽  
Arnaud Jeanvoine ◽  
Sharon Mc Connell ◽  
Alison Gehred ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cochrane Library ◽  
Neurodevelopmental Outcomes ◽  
Frequency Following Response ◽  
Ovid Medline ◽  
Published Evidence ◽  
Mesh Terms ◽  
Potential Applicability ◽  
Clinical Potential

Purpose We sought to critically analyze and evaluate published evidence regarding feasibility and clinical potential for predicting neurodevelopmental outcomes of the frequency-following responses (FFRs) to speech recordings in neonates (birth to 28 days). Method A systematic search of MeSH terms in the Cumulative Index to Nursing and Allied HealthLiterature, Embase, Google Scholar, Ovid Medline (R) and E-Pub Ahead of Print, In-Process & Other Non-Indexed Citations and Daily, Web of Science, SCOPUS, COCHRANE Library, and ClinicalTrials.gov was performed. Manual review of all items identified in the search was performed by two independent reviewers. Articles were evaluated based on the level of methodological quality and evidence according to the RTI item bank. Results Seven articles met inclusion criteria. None of the included studies reported neurodevelopmental outcomes past 3 months of age. Quality of the evidence ranged from moderate to high. Protocol variations were frequent. Conclusions Based on this systematic review, the FFR to speech can capture both temporal and spectral acoustic features in neonates. It can accurately be recorded in a fast and easy manner at the infant's bedside. However, at this time, further studies are needed to identify and validate which FFR features could be incorporated as an addition to standard evaluation of infant sound processing evaluation in subcortico-cortical networks. This review identifies the need for further research focused on identifying specific features of the neonatal FFRs, those with predictive value for early childhood outcomes to help guide targeted early speech and hearing interventions.

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