Control of oral absorption of nutritional supplement using lipid-based formulations (LBFs): Application to the poorly water-soluble ingredient

2020 ◽  
Vol 57 ◽  
pp. 101675
Author(s):  
Haruki Higashino ◽  
Keiko Minami ◽  
Makoto Kataoka ◽  
Namino Tomimori ◽  
Tomohiro Rogi ◽  
...  
Keyword(s):  
Oral Absorption ◽  
Nutritional Supplement ◽  
Water Soluble ◽  
Poorly Water Soluble

Formulation and Food Effects on the Oral Absorption of a Poorly Water Soluble, Highly Permeable Antiretroviral Agent

2002 ◽  
Vol 91 (6) ◽  
pp. 1390-1395 ◽  
Author(s):  
Bruce J. Aungst ◽  
Nhung H. Nguyen ◽  
Nancy J. Taylor ◽  
Dilbir S. Bindra
Keyword(s):  
Oral Absorption ◽  
Water Soluble ◽  
Food Effects ◽  
Poorly Water Soluble

Natural Polymers in Fast Dissolving Tablets

2021 ◽  
pp. 2859-2866
Author(s):  
Ratnaparkhi M.P. ◽  
Karnawat G.R. ◽  
Andhale R.S.
Keyword(s):  
Geriatric Patients ◽  
Nutritional Supplement ◽  
Synthetic Polymers ◽  
Oral Route ◽  
Water Soluble ◽  
Natural Polymers ◽  
Disintegration Time ◽  
Water Soluble Drug ◽  
Poorly Water Soluble ◽  
Poorly Water Soluble Drug

Oral route is most preferable route of administration for various drugs, because it is convenient, economical, safest route. Fast dissolving tablets are popular nowadays, as they disintegrated in mouth within a few seconds without using water for swallow. Problems like Dysphagia in pediatric and geriatric patients have been overcome by formulating Fast dissolving tablet. Natural polymers are preferable because they are chemically inert, nontoxic, less expensive, biodegradable, and available easily than synthetic polymers. Natural polymers are obtained from the natural origin so they are devoid of any side effect. It is proved from the previous studies that Natural polymers are more-safe and effective than the synthetic polymers. Natural polymers improve the properties of tablet and they are used as binder, diluent, superdisintegrant, they also enhance the solubility of poorly water-soluble drug, decrease the disintegration time and provide nutritional supplement. The aim of the present article is to study various natural polymers used in fast dissolving tablets.

Development of microparticles coated with poly-γ-glutamic acid to improve oral absorption of a poorly water-soluble drug

2019 ◽  
Vol 24 (8) ◽  
pp. 992-1001
Author(s):  
Yuri Ikeuchi-Takahashi ◽  
Yudai Shiokawa ◽  
Kazuki Sekita ◽  
Etsuo Yonemochi ◽  
Hiraku Onishi
Keyword(s):  
Glutamic Acid ◽  
Oral Absorption ◽  
Water Soluble ◽  
Water Soluble Drug ◽  
Poorly Water Soluble ◽  
Poorly Water Soluble Drug

Oral Absorption of Poorly Water-Soluble Drugs: Computer Simulation of Fraction Absorbed in Humans from a Miniscale Dissolution Test

2006 ◽  
Vol 23 (6) ◽  
pp. 1144-1156 ◽  
Author(s):  
Ryusuke Takano ◽  
Kiyohiko Sugano ◽  
Atsuko Higashida ◽  
Yoshiki Hayashi ◽  
Minoru Machida ◽  
...  
Keyword(s):  
Computer Simulation ◽  
Oral Absorption ◽  
Water Soluble ◽  
Dissolution Test ◽  
Poorly Water Soluble Drugs ◽  
Fraction Absorbed ◽  
Water Soluble Drugs ◽  
Poorly Water Soluble

Application of Dissolution/Permeation System for Evaluation of Formulation Effect on Oral Absorption of Poorly Water-Soluble Drugs in Drug Development

2011 ◽  
Vol 29 (6) ◽  
pp. 1485-1494 ◽  
Author(s):  
Makoto Kataoka ◽  
Kiyohiko Sugano ◽  
Claudia da Costa Mathews ◽  
Jing Wen Wong ◽  
Kelly Lane Jones ◽  
...  
Keyword(s):  
Drug Development ◽  
Oral Absorption ◽  
Water Soluble ◽  
Poorly Water Soluble Drugs ◽  
Water Soluble Drugs ◽  
Poorly Water Soluble
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