Overexpression of phosphorylated-ATF2 and STAT3 in cutaneous squamous cell carcinoma, Bowen's disease and basal cell carcinoma

2008 ◽  
Vol 51 (3) ◽  
pp. 210-215 ◽  
Author(s):  
Si-Yuan Chen ◽  
Satoshi Takeuchi ◽  
Yoichi Moroi ◽  
Sayaka Hayashida ◽  
Makiko Kido ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Basal Cell ◽  
Cutaneous Squamous Cell Carcinoma ◽  
Bowen’S Disease ◽  
Bowen's Disease

scholarly journals Methyltransferases in the Pathogenesis of Keratinocyte Cancers

Cancers ◽  
2021 ◽  
Vol 13 (14) ◽  
pp. 3402
Author(s):  
Eun Kyung Ko ◽  
Brian C. Capell
Keyword(s):  
Gene Expression ◽  
Squamous Cell Carcinoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Basal Cell ◽  
Histone Methylation ◽  
Cutaneous Squamous Cell Carcinoma ◽  
Therapeutic Approaches ◽  
Novel Therapeutic

Recent evidence suggests that the disruption of gene expression by alterations in DNA, RNA, and histone methylation may be critical contributors to the pathogenesis of keratinocyte cancers (KCs), made up of basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC), which collectively outnumber all other human cancers combined. While it is clear that methylation modifiers are frequently dysregulated in KCs, the underlying molecular and mechanistic changes are only beginning to be understood. Intriguingly, it has recently emerged that there is extensive cross-talk amongst these distinct methylation processes. Here, we summarize and synthesize the latest findings in this space and highlight how these discoveries may uncover novel therapeutic approaches for these ubiquitous cancers.

Risk of cutaneous squamous cell carcinoma after treatment of basal cell carcinoma with vismodegib

2017 ◽  
Vol 77 (4) ◽  
pp. 713-718 ◽  
Author(s):  
Tina Bhutani ◽  
Michael Abrouk ◽  
Camelia S. Sima ◽  
Natalia Sadetsky ◽  
Jeannie Hou ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Basal Cell ◽  
Cutaneous Squamous Cell Carcinoma

Perineural Invasion of Cutaneous Squamous Cell Carcinoma and Basal Cell Carcinoma

2008 ◽  
Vol 34 (12) ◽  
pp. 1642-1651
Author(s):  
DAVID E. GEIST ◽  
MARIA GARCIA-MOLINER ◽  
MARKUS M. FITZEK ◽  
HANNAH CHO ◽  
GARY S. ROGERS
Keyword(s):  
Squamous Cell Carcinoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Basal Cell ◽  
Perineural Invasion ◽  
Cutaneous Squamous Cell Carcinoma
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