scholarly journals Fasting glucose and insulin resistance trajectories during young adulthood and mid-life cardiac structure and function

2019 ◽  
Vol 33 (5) ◽  
pp. 356-362
Author(s):  
Michael P. Bancks ◽  
Mercedes R. Carnethon ◽  
Lisa S. Chow ◽  
Samuel S. Gidding ◽  
David R. Jacobs ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Young Adulthood ◽  
Fasting Glucose ◽  
Structure And Function ◽  
Cardiac Structure ◽  
Cardiac Structure And Function ◽  
And Function

scholarly journals Visit-to-Visit Fasting Glucose Variability in Young Adulthood and Cardiac Structure and Function at Midlife: The CARDIA Study

2021 ◽  
Vol 8 ◽  
Author(s):  
Zhenyu Xiong ◽  
Peihan Xie ◽  
Jiaying Li ◽  
Zhi-chong Chen ◽  
Yifen Lin ◽  
...  
Keyword(s):  
Young Adulthood ◽  
Fasting Glucose ◽  
Glycemic Variability ◽  
Glucose Variability ◽  
Left Ventricular ◽  
Structure And Function ◽  
Cardiac Structure ◽  
Early Peak ◽  
Cardiac Structure And Function ◽  
And Function

Glycemic variability was found associated with left ventricular structure and function in type 2 diabetes. But it is still unclear that whether the greater visit-to-visit fasting glucose (FG) variability in young adulthood among the community population is associated with cardiac function alteration and cardiac remodeling at midlife. The community-based prospective cohort study of Coronary Artery Risk in Young Adult (CARDIA) recruited young participants at the baseline age of 18–30 years during the period of 1985–1986 (Year 0). FG was measured at Year 0, 2, 10, 15, 20, and 25. The echocardiographic evaluation of cardiac structure and function was conducted at year 25. A total of 2,600 young adults mean (SD) aged at 24.9 years (3.6) of which 57.3% were women and 46.7% were African Americans had been included in the study. After multivariable adjusted, higher SD of mean FG (SDFG) is associated with lower early peak diastolic septal mitral annular velocity (e') (β [SE], −0.214 [0.080], P < 0.01) and higher E/e' (β [SE], 0.307 [0.094], P < 0.01), and higher coefficient of variation of the mean FG (CVFG) is also associated with lower e' (β [SE], −0.141[0.066], P < 0.05) and higher E/e' (β [SE], 0.204 [0.078], P < 0.01). The higher average real variation of mean FG (ARVFG) is associated with higher E/e' (β [SE], 0.178 [0.085], P < 0.05) and higher left ventricular mass index (LVMI) (β [SE], 1.240 [0.618], P < 0.05). The higher FG variability in young adulthood is associated with the subclinical change of left ventricular (LV) diastolic function at midlife.

scholarly journals Kashmiri Wazwan: Are We Listening to Our Endothelium?

JMS SKIMS ◽  
2013 ◽  
Vol 16 (2) ◽  
pp. 72-74
Author(s):  
M Fuad Jan ◽  
Suhail Allaqband
Keyword(s):  
Insulin Resistance ◽  
Cardiac Remodeling ◽  
Experimental Models ◽  
Structure And Function ◽  
Cardiac Structure ◽  
Unsaturated Lipid ◽  
Diet Induced Obesity ◽  
Blood Pressure Homeostasis ◽  
Cardiac Structure And Function ◽  
And Function

In animal models of diet-induced obesity, hypercaloric (4.6 Kcal/g) diets have been shown to have metabolic hormonal effects, including hyperglycemia, insulin resistance and changes in leptin profiles 1, as well as undesirable effects on blood pressure homeostasis and even cardiac remodeling. Such effects have been directly and inversely correlated with saturated and unsaturated lipid consumption, respectively. In these experimental models, it also has been elegantly demonstrated that a variety of alterations in cardiac structure and function occur due to reduced myofilament Ca2+ sensitivity, alterations in Ca2+ handling proteins and beta-adrenergic receptors2-5. JMS 2013;16(2):72-74

scholarly journals Fitness in Young Adulthood and Long-Term Cardiac Structure and Function

2017 ◽  
Vol 5 (5) ◽  
pp. 347-355 ◽  
Author(s):  
Ambarish Pandey ◽  
Norrina B. Allen ◽  
Colby Ayers ◽  
Jared P. Reis ◽  
Henrique T. Moreira ◽  
...  
Keyword(s):  
Young Adulthood ◽  
Structure And Function ◽  
Cardiac Structure ◽  
Cardiac Structure And Function ◽  
And Function

scholarly journals Cardiac structure and function and insulin resistance in morbid obese patients: does superobesity play a further role?

2013 ◽  
Vol 34 (suppl 1) ◽  
pp. P737-P737
Author(s):  
F. Antonini-Canterin ◽  
A. D. Mateescu ◽  
V. Di Bello ◽  
S. Carerj ◽  
C. Zito ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Structure And Function ◽  
Cardiac Structure ◽  
Obese Patients ◽  
Morbid Obese ◽  
Cardiac Structure And Function ◽  
And Function

scholarly journals Cardiac Structure and Function and Insulin Resistance in Morbidly Obese Patients: Does Superobesity Play an Additional Role?

Cardiology ◽  
2013 ◽  
Vol 127 (3) ◽  
pp. 144-151 ◽  
Author(s):  
Francesco Antonini-Canterin ◽  
Anca D. Mateescu ◽  
Olga Vriz ◽  
Salvatore La Carrubba ◽  
Vitantonio Di Bello ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Structure And Function ◽  
Morbidly Obese ◽  
Cardiac Structure ◽  
Obese Patients ◽  
Cardiac Structure And Function ◽  
And Function ◽  
Additional Role

scholarly journals Impact of Glucose Intolerance and Insulin Resistance on Cardiac Structure and Function

Circulation ◽  
2003 ◽  
Vol 107 (3) ◽  
pp. 448-454 ◽  
Author(s):  
Martin K. Rutter ◽  
Helen Parise ◽  
Emelia J. Benjamin ◽  
Daniel Levy ◽  
Martin G. Larson ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Glucose Intolerance ◽  
Structure And Function ◽  
Cardiac Structure ◽  
Cardiac Structure And Function ◽  
And Function
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