Scaling up a hollow fibre reactor: A study on non-PGM hollow fibre after-treatments for methane emission control under extreme conditions

Author(s):  
Miguel García-Vázquez ◽  
Pablo Marín ◽  
Salvador Ordóñez ◽  
Kang Li ◽  
Jinkun Tan ◽  
...  
2016 ◽  
Vol 60 (4) ◽  
pp. 228-235 ◽  
Author(s):  
By Agnes Raj

Author(s):  
A. V. Bui ◽  
H. M. Nguyen

A step-by-step procedure for scaling up of an osmotic distillation system from laboratory to pilot plant is discussed. The newly built pilot scale OD system featured a flexibility of using 1 or 2 hollow fibre modules at a time to suit the concentration demands. Three types of hollow fibres were tested on the new system. Pilot trials for OD concentration of apple, grape juices and freeze concentrated (FC) grape juice were successfully carried out to achieve a final concentration up to 65°Brix with fluxes ranging from 2.4 to 0.69kg.m-2.h-1 depending on the fibre types and the operating conditions. Cascade effect was also employed to deal with high viscosity to achieve high concentration. The obtained pilot OD fluxes were comparable to the ones obtained in the lab under similar conditions, and they fitted well with the developed models. Sensory evaluation indicated that OD well preserved the quality attributes of the fruit juices.


2000 ◽  
Author(s):  
Don Augenstein ◽  
Ramin Yazdani ◽  
Rick Moore ◽  
Michelle Byars ◽  
Jeff Kieffer ◽  
...  

2019 ◽  
Vol 4 (6) ◽  
pp. 224-234
Author(s):  
A.A. Sidorenko ◽  
◽  
A.M. Cherdancev ◽  
S.A. Sidorenko ◽  
◽  
...  

Many standard procedures for the purification of proteins in the laboratory do not readily lend themselves to scaling up, whereas, on the other hand, some techniques relatively unsatisfactory in the laboratory are much more effective on a large scale. When producing gram or kilogram quantities of enzymes for use over an extended period, the storage properties and general tractability of the purified products become increasingly important. Hence enzymes from thermophilic sources frequently have advantages over those from mesophiles. The possible economic advantages of simultaneous large-scale multi-enzyme isolation over separate individual enzyme purifications are evaluated. Batchwise adsorption and elution from ion-exchange celluloses frequently replace traditional precipitation techniques in the early stages of a large-scale purification. Dialysis is replaced by concentration, dilution and reconcentration with the use of hollow-fibre ultrafiltration equipment. Antiphonally direct scaling-up of column chromatographic procedures is usually possible. Modifications to column geometry to maximize flow rates are often desirable but purification factors and recoveries comparable with those obtained on the laboratory scale can be achieved relatively easily. Classical affinity chromatographic techniques have not proved so amenable to large-scale work, mainly because of the enormous expense and rather short life of the matrices. However, the quasi-affinity chromatography afforded by the triazine dye conjugates has proved of great benefit. The materials are cheap to prepare. The coupling procedures are both simple and rapid and do not involve the use of noxious chemicals such as cyanogen bromide. Moreover the triazine linkage is more stable under a variety of conditions than the isourea formed in cyanogen bromide coupling. Considerable further exploitation of these versatile matrices is expected.


Author(s):  
Ogechukwu Bose Chukwuma ◽  
Mohd Rafatullah ◽  
Husnul Azan Tajarudin ◽  
Norli Ismail

Discovering novel bacterial strains might be the link to unlocking the value in lignocellulosic bio-refinery as we strive to find alternative and cleaner sources of energy. Bacteria display promise in lignocellulolytic breakdown because of their innate ability to adapt and grow under both optimum and extreme conditions. This versatility of bacterial strains is being harnessed, with qualities like adapting to various temperature, aero tolerance, and nutrient availability driving the use of bacteria in bio-refinery studies. Their flexible nature holds exciting promise in biotechnology, but despite recent pointers to a greener edge in the pretreatment of lignocellulose biomass and lignocellulose-driven bioconversion to value-added products, the cost of adoption and subsequent scaling up industrially still pose challenges to their adoption. However, recent studies have seen the use of co-culture, co-digestion, and bioengineering to overcome identified setbacks to using bacterial strains to breakdown lignocellulose into its major polymers and then to useful products ranging from ethanol, enzymes, biodiesel, bioflocculants, and many others. In this review, research on bacteria involved in lignocellulose breakdown is reviewed and summarized to provide background for further research. Future perspectives are explored as bacteria have a role to play in the adoption of greener energy alternatives using lignocellulosic biomass.


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