Is the outcomes of early ST-segment resolution after thrombolytic therapy in acute myocardial infarction always favorable?

2005 ◽  
Vol 38 (4) ◽  
pp. 354-360 ◽  
Author(s):  
Kevin R. Bainey ◽  
Manohara P.J. Senaratne
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Thrombolytic Therapy ◽  
St Segment

Early assessment of outcome by ST-segment analysis after thrombolytic therapy in acute myocardial infarction

1994 ◽  
Vol 128 (5) ◽  
pp. 851-857 ◽  
Author(s):  
Rüdiger Dissmann ◽  
Rolf Schröder ◽  
Ulrike Busse ◽  
Mathias Appel ◽  
Thomas Brüggemann ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Thrombolytic Therapy ◽  
Early Assessment ◽  
St Segment

The Critical Care Nurse’s Role in the Noninvasive Assessment of Myocardial Reperfusion

1990 ◽  
Vol 1 (1) ◽  
pp. 110-118
Author(s):  
Marlene R. Kleven
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Thrombolytic Therapy ◽  
Standard Of Care ◽  
Reperfusion Therapy ◽  
Myocardial Reperfusion ◽  
Direct Visualization ◽  
Review Of The Literature ◽  
St Segment ◽  
Noninvasive Assessment

Thrombolytic therapy is rapidly becoming the standard of care for the treatment of acute myocardial infarction (AMI). The goal of thrombolytic therapy is clot dissolution in the infarct artery that results in re-establishing blood flow to affected ischemic myocardium. Confirmation of the occurrence of reperfusion can only be established by direct visualization of the coronary artery. Clinical reperfusion markers (dysrhythmias, chest pain relief, ST segment normalization, CK peak values) have also been associated with myocardial reperfusion. These markers are noninvasive and are routinely relied on in the clinical setting. However, a review of the literature reveals that the noninvasive reperfusion markers individually lack reliability in successfully predicting reperfusion status. Because of the importance of establishing the success of reperfusion therapy early in the treatment of AMI, it is critical that the nurse at the bedside be aware of the criteria that can be established to improve the reliability of the reperfusion markers and their limitations.

Resolution of ST-segment elevation in acute myocardial infarction — Early prognostic significance after thrombolytic therapy

Herz ◽  
1999 ◽  
Vol 24 (6) ◽  
pp. 440-447 ◽  
Author(s):  
Joerg Carlsson ◽  
Uwe Kamp ◽  
Dirk Härtel ◽  
Johannes Brockmeier ◽  
Rainer Meierhenrich ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Thrombolytic Therapy ◽  
Prognostic Significance ◽  
St Segment Elevation ◽  
St Segment

scholarly journals Early ST-segment elevation acute myocardial infarction after thrombolytic therapy for acute ischemic stroke

Medicine ◽  
2018 ◽  
Vol 97 (50) ◽  
pp. e13347 ◽  
Author(s):  
Maria Mirabela Manea ◽  
Dorin Dragoş ◽  
Emanuel Stoica ◽  
Adrian Bucşa ◽  
Ioana Marinică ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Ischemic Stroke ◽  
Thrombolytic Therapy ◽  
Acute Ischemic Stroke ◽  
St Segment Elevation ◽  
St Segment ◽  
Elevation Acute Myocardial Infarction

scholarly journals Что мы знаем сегодня об отечественном тромболитическом препарате рекомбинантная проурокиназа (пуролаза)

2019 ◽  
Author(s):  
S.G. Milenkina ◽  
E.P. Delver ◽  
A.A. Belogurov ◽  
R.SH. Bibilashvilli ◽  
E.V. Arzamastsev ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Thrombolytic Therapy ◽  
Coronary Intervention ◽  
Technical Aspects ◽  
St Segment Elevation ◽  
Thrombolytic Drug ◽  
St Segment ◽  
Percutaneous Coronary ◽  
Current Guidelines

В обзоре представлены основные данные о создании отечественного тромболитического препарата III поколения рекомбинантной проурокиназы и применении ее у пациентов с острым инфарктом миокарда с подъемом сегмента ST (ИМпST). Современные рекомендации отдают предпочтение первичному чрескожному коронарному вмешательству (ЧКВ). Однако ряд логистических и технических особенностей нередко делает проведение ЧКВ в рекомендованные сроки невозможным, и медикаментозная реперфузия остается методом выбора. Своевременная тромболитическая терапия (ТЛТ) позволяет уменьшить время до начала реперфузии и улучшить прогноз больного. Накоплен значительный опыт догоспитального и госпитального применения рекомбинантной проурокиназы. В статье рассмотрены результаты основных исследований эффективности и безопасности, а также особенностей применения рекомбинантной проурокиназы, в том числе при использовании фармакоинвазивного подхода к лечению ИМпST. Ключевые слова: острый инфаркт миокарда с подъемом сегмента ST, тромболитическая терапия, пуролаза, рекомбинантная проурокиназа, фармакоинвазивный подход.The review presents the main data on the development of thrombolytic drug of the III generation of recombinant prourokinase produced in Russia and its administration in patients with acute myocardial infarction with ST segment elevation (STEMI). Current guidelines prefer primary percutaneous coronary intervention (PCI). However, a number of logistical and technical aspects often make it impossible to carry out PCI within the recommended time, and drug reperfusion remains the method of choice. Well-timed thrombolytic therapy (TLT) can reduce the time before reperfusion and improve the patients prognosis. Significant experience in pre-hospital and hospital is adepted at use of recombinant prourokinase. The article considers the results of the main studies of the effectiveness and safety, as well as the aspects of the use of recombinant prourokinase, including the use of pharmacoinvasive approach to the treatment of STEMI. Key words: acute myocardial infarction with ST-segment elevation, thrombolytic therapy, Purolase, pharmacoinvasive approach.

Ratio of ST-Segment and myoglobin slopes to estimate myocardial salvage during thrombolytic therapy for acute myocardial infarction

1993 ◽  
Vol 71 (15) ◽  
pp. 1362-1365 ◽  
Author(s):  
Julie M. Baskin ◽  
Michelle L. Wilkins ◽  
E.Magnus Ohman ◽  
Peter Clemmensen ◽  
Peer Grande ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Thrombolytic Therapy ◽  
Myocardial Salvage ◽  
St Segment

ST Elevation is not Always Equivalent to Acute Myocardial Infarction: a Case of Brugada Syndrome

2003 ◽  
Vol 10 (2) ◽  
pp. 121-123
Author(s):  
YF Choi ◽  
AYC Siu ◽  
TW Wong ◽  
CC Lau
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Emergency Department ◽  
Thrombolytic Therapy ◽  
Brugada Syndrome ◽  
Diagnostic Tools ◽  
St Segment Elevation ◽  
St Segment ◽  
St Elevation ◽  
Electrocardiogram Ecg

Acute myocardial infarction (AMI) is one of the most alerting situations in emergency department. Electrocardiogram (ECG) is one of the most important diagnostic tools and the decision about thrombolytic therapy is usually based upon ECG findings when clinically suspicious. However, ST segment elevation is not always equivalent to acute myocardial infarction. We present a rare syndrome whose ECG shows persistent ST elevation not related to AMI.

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