Protective and immunomodulatory effect of Gingyo-san in a murine model of acute lung inflammation

2007 ◽  
Vol 111 (2) ◽  
pp. 418-426 ◽  
Author(s):  
Chia-Chou Yeh ◽  
Chih-Che Lin ◽  
Shulhn-Der Wang ◽  
Che-Ming Hung ◽  
Ming-Hsien Yeh ◽  
...  
Keyword(s):  
Murine Model ◽  
Lung Inflammation ◽  
Immunomodulatory Effect ◽  
Acute Lung Inflammation

Inhalation of glycopyrronium inhibits cigarette smoke-induced acute lung inflammation in a murine model of COPD

2014 ◽  
Vol 18 (2) ◽  
pp. 358-364 ◽  
Author(s):  
Liang-liang Shen ◽  
Ya-nan Liu ◽  
Hui-juan Shen ◽  
Chong Wen ◽  
Yong-liang Jia ◽  
...  
Keyword(s):  
Cigarette Smoke ◽  
Murine Model ◽  
Lung Inflammation ◽  
Acute Lung Inflammation

scholarly journals Treatment of acute lung inflammation by pulmonary delivery of anti-TNF-α siRNA with PAMAM dendrimers in a murine model

2020 ◽  
Vol 156 ◽  
pp. 114-120 ◽  
Author(s):  
Adam Bohr ◽  
Nicolas Tsapis ◽  
Camilla Foged ◽  
Ilaria Andreana ◽  
Mingshi Yang ◽  
...  
Keyword(s):  
Murine Model ◽  
Lung Inflammation ◽  
Pulmonary Delivery ◽  
Pamam Dendrimers ◽  
Acute Lung Inflammation ◽  
Tnf Α

C-peptide attenuates acute lung inflammation in a murine model of hemorrhagic shock and resuscitation by reducing gut injury

2017 ◽  
Vol 83 (2) ◽  
pp. 256-262 ◽  
Author(s):  
Raymond L.C. Kao ◽  
Xuemei Xu ◽  
Anargyros Xenocostas ◽  
Neil Parry ◽  
Tina Mele ◽  
...  
Keyword(s):  
Hemorrhagic Shock ◽  
Murine Model ◽  
Lung Inflammation ◽  
Acute Lung Inflammation ◽  
C Peptide

scholarly journals Combined In Vitro and In Vivo Approaches to Propose a Putative Adverse Outcome Pathway for Acute Lung Inflammation Induced by Nanoparticles: A Study on Carbon Dots

Nanomaterials ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 180
Author(s):  
Maud Weiss ◽  
Jiahui Fan ◽  
Mickaël Claudel ◽  
Luc Lebeau ◽  
Françoise Pons ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Lung Inflammation ◽  
Adverse Outcome ◽  
Cellular Responses ◽  
Target Cells ◽  
Inflammasome Activation ◽  
Adverse Outcome Pathway ◽  
Acute Lung Inflammation

With the growth of nanotechnologies, concerns raised regarding the potential adverse effects of nanoparticles (NPs), especially on the respiratory tract. Adverse outcome pathways (AOP) have become recently the subject of intensive studies in order to get a better understanding of the mechanisms of NP toxicity, and hence hopefully predict the health risks associated with NP exposure. Herein, we propose a putative AOP for the lung toxicity of NPs using emerging nanomaterials called carbon dots (CDs), and in vivo and in vitro experimental approaches. We first investigated the effect of a single administration of CDs on mouse airways. We showed that CDs induce an acute lung inflammation and identified airway macrophages as target cells of CDs. Then, we studied the cellular responses induced by CDs in an in vitro model of macrophages. We observed that CDs are internalized by these cells (molecular initial event) and induce a series of key events, including loss of lysosomal integrity and mitochondrial disruption (organelle responses), as well as oxidative stress, inflammasome activation, inflammatory cytokine upregulation and macrophage death (cellular responses). All these effects triggering lung inflammation as tissular response may lead to acute lung injury.

scholarly journals Inhibitory effect of Zanthoxylum bungeanum seed oil on ovalbumin-induced lung inflammation in a murine model of asthma

2016 ◽  
Vol 13 (5) ◽  
pp. 4289-4302 ◽  
Author(s):  
JUN-QIN WANG ◽  
XIAO-WEI LI ◽  
MINGYI LIU ◽  
SHENG-CHUN WANG ◽  
ZENG-FA CAO
Keyword(s):  
Murine Model ◽  
Lung Inflammation ◽  
Seed Oil ◽  
Inhibitory Effect ◽  
Zanthoxylum Bungeanum
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