The Aurora kinase inhibitor VE-465 has anticancer effects in pre-clinical studies of human hepatocellular carcinoma

2009 ◽  
Vol 50 (3) ◽  
pp. 518-527 ◽  
Author(s):  
Zhong-Zhe Lin ◽  
Hey-Chi Hsu ◽  
Chih-Hung Hsu ◽  
Pei-Yen Yeh ◽  
Chi-Ying F. Huang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Clinical Studies ◽  
Kinase Inhibitor ◽  
Aurora Kinase ◽  
Human Hepatocellular Carcinoma ◽  
Aurora Kinase Inhibitor ◽  
Anticancer Effects

scholarly journals A quantitative proteomic response of hepatocellular carcinoma Hep3B cells to danusertib, a pan-Aurora kinase inhibitor

2018 ◽  
Vol 9 (12) ◽  
pp. 2061-2071 ◽  
Author(s):  
Qiaohua Zhu ◽  
Xinfa Yu ◽  
Zhi-Wei Zhou ◽  
Meihua Luo ◽  
Chengyu Zhou ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Kinase Inhibitor ◽  
Aurora Kinase ◽  
Aurora Kinase Inhibitor ◽  
Hep3b Cells ◽  
Proteomic Response

scholarly journals Cell Cycle Interference Contributes to the Anticancer Synergy Between Radiotherapy and Aurora Kinase Inhibitor VE-465 in Hepatocellular Carcinoma

2014 ◽  
Vol 25 ◽  
pp. ii20
Author(s):  
Lin Zhong-Zhe ◽  
Chou Chia-Hung ◽  
Cheng Ann-Lii ◽  
Liu Wei-Lin ◽  
Cheng Jason Chia-Hsien
Keyword(s):  
Hepatocellular Carcinoma ◽  
Cell Cycle ◽  
Kinase Inhibitor ◽  
Aurora Kinase ◽  
Aurora Kinase Inhibitor

scholarly journals Radiosensitization by combining an aurora kinase inhibitor with radiotherapy in hepatocellular carcinoma through cell cycle interruption

2014 ◽  
Vol 135 (2) ◽  
pp. 492-501 ◽  
Author(s):  
Zhong-Zhe Lin ◽  
Chia-Hung Chou ◽  
Ann-Lii Cheng ◽  
Wei-Lin Liu ◽  
Jason Chia-Hsien Cheng
Keyword(s):  
Hepatocellular Carcinoma ◽  
Cell Cycle ◽  
Kinase Inhibitor ◽  
Aurora Kinase ◽  
Aurora Kinase Inhibitor

scholarly journals Aurora Kinase Inhibitor PHA-739358 Suppresses Growth of Hepatocellular Carcinoma In Vitro and in a Xenograft Mouse Model

Neoplasia ◽  
2009 ◽  
Vol 11 (9) ◽  
pp. 934-944 ◽  
Author(s):  
Daniel Benten ◽  
Gunhild Keller ◽  
Alexander Quaas ◽  
Jorg Schrader ◽  
Artur Gontarewicz ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Mouse Model ◽  
Kinase Inhibitor ◽  
Aurora Kinase ◽  
Aurora Kinase Inhibitor ◽  
Xenograft Mouse Model

scholarly journals The human Aurora kinase inhibitor danusertib is a lead compound for anti-trypanosomal drug discovery via target repurposing

2013 ◽  
Vol 62 ◽  
pp. 777-784 ◽  
Author(s):  
Stefan O. Ochiana ◽  
Vidya Pandarinath ◽  
Zhouxi Wang ◽  
Rishika Kapoor ◽  
Mary Jo Ondrechen ◽  
...  
Keyword(s):  
Drug Discovery ◽  
Kinase Inhibitor ◽  
Aurora Kinase ◽  
Lead Compound ◽  
Aurora Kinase Inhibitor ◽  
Target Repurposing

A phase l study of three different dosing schedules of the oral aurora kinase inhibitor MSC1992371A in patients with solid tumors

2013 ◽  
Vol 9 (3) ◽  
pp. 215-224 ◽  
Author(s):  
M. Mita ◽  
M. Gordon ◽  
N. Rejeb ◽  
A. Gianella-Borradori ◽  
V. Jego ◽  
...  
Keyword(s):  
Solid Tumors ◽  
Kinase Inhibitor ◽  
Aurora Kinase ◽  
Aurora Kinase Inhibitor
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