LPCAT1 promotes cutaneous squamous cell carcinoma via EGFR-mediated AKT/p38MAPK signaling pathways

2021 ◽  
Author(s):  
Yingjian Huang ◽  
Yuqian Wang ◽  
Yan Wang ◽  
Ning Wang ◽  
Qiqi Duan ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Signaling Pathways ◽  
Squamous Cell ◽  
Cutaneous Squamous Cell Carcinoma ◽  
P38mapk Signaling

scholarly journals Pharmacologically Induced Cutaneous Squamous Cell Carcinoma

2020 ◽  
Author(s):  
Natalia García
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Signaling Pathways ◽  
Squamous Cell ◽  
Molecular Mechanisms ◽  
Cutaneous Squamous Cell Carcinoma ◽  
Clinical Behavior ◽  
Mutational Burden ◽  
Therapeutic Landscape ◽  
Increased Risk

Cutaneous squamous cell carcinoma (CSCC) is the second most frequent cancer in humans and its incidence continues to rise. Although CSCC usually display a benign clinical behavior, it can be both locally invasive and metastatic. The signaling pathways involved in CSCC development have given rise to targetable molecules in recent decades. In addition, the high mutational burden and increased risk of CSCC in patients under immunosuppression were part of the rationale for developing the immunotherapy for CSCC that has changed the therapeutic landscape. Several drugs have been developed for CSCC treatment, but the disease may actually be induced by drugs as well. Molecular mechanisms underlie pharmacologically-induced CSCC, and a sound knowledge of them could help physicians better tackle this tumor. 

A Case of Anti-TIF1-γ Antibody-positive Dermatomyositis with Cutaneous Squamous Cell Carcinoma

2018 ◽  
Vol 80 (4) ◽  
pp. 331-335
Author(s):  
Reika FUKUCHI ◽  
Sayaka KUWATSUKA ◽  
Yukie SATO ◽  
Yutaka KUWATSUKA ◽  
Atsushi UTANI
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cutaneous Squamous Cell Carcinoma

Multidisciplinary Expert-Driven Consensus on the Evolving Treatment of Patients with Advanced Cutaneous Squamous Cell Carcinoma

2019 ◽  
Vol 3 ◽  
pp. S50
Author(s):  
Michael R Migden ◽  
Todd E Schlesinger ◽  
Chrysalyne D Schmults ◽  
Scott M Dinehart ◽  
Robert L Ferris ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cutaneous Squamous Cell Carcinoma

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