WITHDRAWN: Rapid sensitivity testing of mycobacterium tuberculosis using the mycobacteria growth indicator tube system (MGIT)

2006 ◽  
Author(s):  
E.J. Ridgway ◽  
K. Sethi ◽  
K. Thickett ◽  
R. Townsend
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Tube System ◽  
Sensitivity Testing ◽  
Indicator Tube ◽  
Growth Indicator

scholarly journals Isoniazid Resistance in Mycobacterium tuberculosis Is a Heterogeneous Phenotype Composed of Overlapping MIC Distributions with Different Underlying Resistance Mechanisms

2019 ◽  
Vol 63 (7) ◽  
Author(s):  
Arash Ghodousi ◽  
Elisa Tagliani ◽  
Eranga Karunaratne ◽  
Stefan Niemann ◽  
Jennifer Perera ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Resistance Mechanisms ◽  
Whole Genome ◽  
Tube System ◽  
Isoniazid Resistance ◽  
Content Type ◽  
Indicator Tube ◽  
Promoter Mutations ◽  
Level Resistance ◽  
Growth Indicator

ABSTRACT MIC testing using the Bactec mycobacteria growth indicator tube system 960 of 70 phylogenetically diverse, isoniazid-resistant clinical strains of Mycobacterium tuberculosis revealed a complex pattern of overlapping MIC distributions. Whole-genome sequencing explained most of the levels of resistance observed. The MIC distribution of strains with only inhA promoter mutations was split by the current concentration endorsed by the Clinical and Laboratory Standards Institute to detect low-level resistance to isoniazid and is, consequently, likely not optimally set.

Comparison of the Manual Mycobacteria Growth Indicator Tube and the Etest with the Method of Proportion for Susceptibility Testing of Mycobacterium tuberculosis

Chemotherapy ◽  
2006 ◽  
Vol 52 (4) ◽  
pp. 174-177 ◽  
Author(s):  
E. Fegou ◽  
E. Jelastopulu ◽  
S. Nicolaou ◽  
M. Sevdali ◽  
S. Anagnostou ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Susceptibility Testing ◽  
Indicator Tube ◽  
Growth Indicator
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