Central nervous system infections among individuals with and without end-stage renal disease

2013 ◽  
Vol 67 (1) ◽  
pp. 19-26 ◽  
Author(s):  
Jesper D. Gunst ◽  
Søren Jensen-Fangel ◽  
Bente Jespersen ◽  
Lars Østergaard ◽  
Ole S. Søgaard
2015 ◽  
Vol 2015 ◽  
pp. 1-12 ◽  
Author(s):  
Hui Juan Chen ◽  
Long Jiang Zhang ◽  
Guang Ming Lu

Patients with end-stage renal disease (ESRD) suffer from a number of complex neurological complications including vascular damage and cognitive dysfunction. It is of great significance to detect the neurological complications and improve the prognosis of ESRD patients. Many new noninvasive MRI techniques have been steadily used for the diagnosis of occult central nervous system complications in ESRD patients. This gives an opportunity to understand the pathophysiological mechanisms of these neurological disorders. This paper is a review that presents the MRI findings of occult brain damage in ESRD patients, outlines the applications of advanced MRI techniques, and introduces a brief perspective in this study field.


Author(s):  
Joshua S. Hundert ◽  
Rashmi Verma ◽  
Ritika Suri ◽  
Anika T. Singh ◽  
Ajay Singh

In the United Syates, chronic kidney disease (CKD) affects approximately 5% to 10% of the general population. It is estimated that about 20 million Americans have some degree of CKD. Central nervous system (CNS) abnormalities are common in patients with CKD, especially in those individuals with end stage renal disease (ESRD) who require renal replacement therapy, such as dialysis or transplant. Neurological symptoms in patients with CKD may range from mild altered sensorium and cognitive dysfunction to tremors and coma. By the time patients require renal replacement therapy, some patients may have uremia, a clinical syndrome with protean manifestations.


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