2D-titanium carbide (MXene) based selective electrochemical sensor for simultaneous detection of ascorbic acid, dopamine and uric acid

2021 ◽  
Vol 72 ◽  
pp. 122-131
Author(s):  
Nagaraj Murugan ◽  
Rajendran Jerome ◽  
Murugan Preethika ◽  
Anandhakumar Sundaramurthy ◽  
Ashok K. Sundramoorthy
Keyword(s):  
Ascorbic Acid ◽  
Uric Acid ◽  
Titanium Carbide ◽  
Electrochemical Sensor ◽  
Simultaneous Detection

A multifunctional electrochemical sensor for the simultaneous detection of ascorbic acid, dopamine, uric acid, and nitrite

2020 ◽  
Author(s):  
Huimin Wang ◽  
Xueli Zhang ◽  
Shuangjue Wang ◽  
Hanyue Ma ◽  
Xia Wang
Keyword(s):  
Ascorbic Acid ◽  
Uric Acid ◽  
Human Serum ◽  
Electrochemical Sensor ◽  
Chronic Diseases ◽  
Metabolic Disorders ◽  
Simultaneous Detection ◽  
Serum Samples ◽  
Buffer Solution ◽  
Human Serum Samples

Abstract Background Ascorbic acid (AA), dopamine (DA), uric acid (UA), and nitrite (NO2−) are essential biomarkers for human metabolism, and can be used to indicate some chronic diseases and metabolic disorders, including scurvy, Parkinson’s disease, hyperuricemia, and kidney disease. Objective A multifunctional electrochemical sensor that can integrate the detection of these species was constructed using nanoporous gold (NPG) as a recognition element to modify glassy carbon electrode (GCE). Methods The electrochemical performance of the multifunctional electrochemical sensor was investigated toward AA, DA, UA, and NO2− in citrate buffer solution (CBS, 100 mM, pH 4.0) and human serum using cyclic voltammetry (CV) and differential pulse voltammetry (DPV) methods. Results In the quaternary mixture detection, the resulting NPG/GCE electrode displayed four independent oxidation peaks with wide peak separations. Further, the NPG/GCE electrode showed good linear responses with the sensitivities of 32, 1103, 71, and 147 μA/mM/cm2 and the detection limits of 1.58, 0.17, 0.37, and 0.36 μM for AA, DA UA, and NO2−, respectively. Additionally, the NPG/GCE electrode exhibited great anti-interference and was successfully applied in human serum samples. Conclusions These results indicate that the NPG/GCE electrode can simultaneously and selectively detect AA, DA, UA, and NO2−, which has the potential for application and diagnosis in the screening and diagnosis of chronic diseases and metabolic disorders. Highlights A multianalyte electrochemical sensor was fabricated for human metabolites detection. The sensor displayed good performance in the simultaneous detection of AA, DA, UA, and NO2−, and applied to human serum samples.

Gold nanoparticle-decorated MoS2 nanosheets for simultaneous detection of ascorbic acid, dopamine and uric acid

RSC Advances ◽  
2014 ◽  
Vol 4 (52) ◽  
pp. 27625 ◽  
Author(s):  
Haofan Sun ◽  
Jie Chao ◽  
Xiaolei Zuo ◽  
Shao Su ◽  
Xingfen Liu ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Uric Acid ◽  
Gold Nanoparticle ◽  
Simultaneous Detection ◽  
Mos2 Nanosheets

3DGH-Fc based electrochemical sensor for the simultaneous determination of ascorbic acid, dopamine and uric acid

2017 ◽  
Vol 799 ◽  
pp. 459-467 ◽  
Author(s):  
Qing Zhu ◽  
Jing Bao ◽  
Danqun Huo ◽  
Mei Yang ◽  
Huixiang Wu ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Uric Acid ◽  
Electrochemical Sensor ◽  
Simultaneous Determination
Sign in / Sign up

Export Citation Format

Share Document