The Effect of Increasing Blood Flow Rate on Severity of Uremic Pruritus in Hemodialysis Patients: A Single Clinical Trial

2018 ◽  
Vol 110 (3) ◽  
pp. 270-275 ◽  
Author(s):  
Mansooreh Aliasgharpour ◽  
Soheila Zabolypour ◽  
Ahmadali Asadinoghabi ◽  
Hamid Haghani ◽  
Mahboub Lesanpezeshki
1992 ◽  
Vol 15 (8) ◽  
pp. 470-474 ◽  
Author(s):  
I.D. Daniels ◽  
G.M. Berlyne ◽  
R.H. Barth

We studied the effect of extracorporeal blood flow rate (BFR) on access recirculation (recirc) in 19 hemodialysis patients. BUN was determined in simultaneous peripheral (P), arterial (A), and venous (V) blood obtained at BFRs of 200, 400 and 600 ml/min. Percent recirc was calculated for each BFR using the formula (P-A) / (P-V) X 100. Venous drip-chamber (VP) and pre-blood-pump (AP) pressures were measured at each BFR. Fistulograms were performed in 10 patients, and stenoses were identified in 5, all at the proximal (arterial) end of the access. Recirc increased with increasing BFR from 200 to 400 ml/min but increased little from 400 to 600 ml/min. At all BFRs recirc in the stenotic patients was higher than that of non-stenotic or unstudied patients. Urea clearance, corrected for recirc, rose with blood flow both in stenotic and non-stenotic patients. There were no differences in AP or in VP between stenotic and non-stenotic patients. At BFR ≥ 400 ml/min, a recirc threshold of 15% identified stenoses with sensitivity 100% and specificity 71%. We conclude (1) recirc increases with increasing BFR but not enough to outweight the concomitant increase in urea clearance; (2) significant access stenosis and recirc may be present even with low VP; (3) recirc was associated with arterial side stenoses; (4) at BFR ≥ 400 ml/min, access stenosis is associated with recirc > 15%.


2020 ◽  
Author(s):  
FAYE Moustapha ◽  
Niakhaleen KEITA ◽  
Maria Faye ◽  
Yousseph BERDAI ◽  
Ahmed Tall LEMRABOTT ◽  
...  

Abstract Background: The objective of this work was to assess the impact of the decrease in dialysate flow rate on the dialysis dose delivered (spKt /V) to chronic hemodialysis patients and to estimate the resulting water saving. Methods: It was a prospective 4-week-period study that included chronic hemodialysis patients with clinical and hemodynamic stability. The patients successively underwent hemodialysis with a dialysate flow rate of 500 ml / min, at 1, 1.2 and 1.5 times the blood flow rate. Each dialysate flow rate was applied for one week. During these 4 weeks, the following parameters were kept constant: duration of dialysis, blood flow rate, anticoagulation, membrane nature and surface. Results: Forty-five chronic hemodialysis patients were included with a mean age of 48.4 ± 12.07 years. The weekly average spKt/V was statistically higher with a dialysate flow rate at 1.5 times the blood flow rate compared to the dialysate flow at 500 mL / min (p = 0.001). The proportion of patients achieving a standardized dialysis dose ≥ 1.4 was statistically higher with dialysate flow at 500 mL / min (64.4%) compared to dialysate flow at 1 or 1.2 times the blood flow rate which were 57.8% and 55.6%, respectively. It was statistically higher with a dialysate flow at 1.5 times the blood flow (93.3%) compared to the dialysate flow at 500 mL / min (p = 0.036). The dialysate volume used with a dialysate flow rate of 500 mL / min was higher compared to the other dialysate flow rates (p = 0.0001). Conclusions: An adequate dialysis dose could be achieved with a dialysate flow rate of 1.5 times the blood flow rate, thereby saving significant amount of water.


2015 ◽  
Vol 40 (Suppl. 1) ◽  
pp. 12-16 ◽  
Author(s):  
Tadao Akizawa ◽  
Fumihiko Koiwa

Many pieces of evidence of online hemodiafiltration (HDF) have been reported, and the clinical advantage of postdilution online HDF with sufficient substitution is now established. After the approval of online HDF in 2012, the number of online HDF patients has been dramatically increasing in Japan and reached 10% of the total dialysis population at the end of 2013. One of the marked characteristics of Japanese online HDF is a widespread use of predilution treatment and, in 2013, 90.8% of online HDFs were carried out with the predilution mode. The main reason for the wide use of predilution online HDF results from the low blood flow rate in Japan, by which it is difficult to substitute a sufficient volume during the limited treatment time. Other reasons to choose the predilution mode include the reduction of albumin loss and the suppression of membrane fouling during treatment. Contrary to postdilution treatment, adequate clinical evidence has not been reported for predilution online HDF to provide a better outcome of the patients. A further clinical trial is expected to elucidate the clinical advantages over conventional hemodialysis for predilution online HDF.


2020 ◽  
Vol 7 (2) ◽  
pp. 94
Author(s):  
Hedayat Jafari ◽  
Mohsen Nezami Ghale Noee ◽  
Jalil Hasani ◽  
Saeed Erfanpoor

1970 ◽  
Vol 1 (1) ◽  
Author(s):  
Leng Hui

Abstract: Objective: To ensure that the patient’s treatment and control of the patient’s blood in the course of long-term dialysis, in order to ensure the blood flow rate at the rate of hemodialysis in the blood vessel of hemodialysis patients, mortality rate. Methods: In many Western countries, it has been found from the experience of long-term accumulation, arteriovenous fistula (AVF) is the first choice for long-term dialysis blood patients, which has a lot of a little bit, not only from the infection rate and blood flow, which has a lot of advantages.But its existence is also a lot of complications, non-thermal Commscope irradiation is a very effective way. Results: The method was compared with the method, and it was found that P <0.05, which was statistically significant. Conclusion: AVF is the preferred method of vascular access in patients with persistent dialysis, which is very easy to be punctured and has a very long time for maintenance. It is very important to carry out the treatment, treatment and surveillance of AVF complications and the use of means.


2006 ◽  
Vol 35 (11) ◽  
pp. 682-688 ◽  
Author(s):  
Suat Unver ◽  
Enes Murat Atasoyu ◽  
T. Rıfkı Evrenkaya

2021 ◽  
Author(s):  
Xinju Zhao ◽  
Qingyu Niu ◽  
Liangying Gan ◽  
Fan Fan Hou ◽  
Xinling Liang ◽  
...  

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