scholarly journals The impact of blood flow rate on dialysis dose and phosphate removal in hemodialysis patients

2018 ◽  
Vol 29 (4) ◽  
pp. 872 ◽  
Author(s):  
Hicham Rafik ◽  
Taoufiq Aatif ◽  
Driss El Kabbaj
2020 ◽  
Author(s):  
FAYE Moustapha ◽  
Niakhaleen KEITA ◽  
Maria Faye ◽  
Yousseph BERDAI ◽  
Ahmed Tall LEMRABOTT ◽  
...  

Abstract Background: The objective of this work was to assess the impact of the decrease in dialysate flow rate on the dialysis dose delivered (spKt /V) to chronic hemodialysis patients and to estimate the resulting water saving. Methods: It was a prospective 4-week-period study that included chronic hemodialysis patients with clinical and hemodynamic stability. The patients successively underwent hemodialysis with a dialysate flow rate of 500 ml / min, at 1, 1.2 and 1.5 times the blood flow rate. Each dialysate flow rate was applied for one week. During these 4 weeks, the following parameters were kept constant: duration of dialysis, blood flow rate, anticoagulation, membrane nature and surface. Results: Forty-five chronic hemodialysis patients were included with a mean age of 48.4 ± 12.07 years. The weekly average spKt/V was statistically higher with a dialysate flow rate at 1.5 times the blood flow rate compared to the dialysate flow at 500 mL / min (p = 0.001). The proportion of patients achieving a standardized dialysis dose ≥ 1.4 was statistically higher with dialysate flow at 500 mL / min (64.4%) compared to dialysate flow at 1 or 1.2 times the blood flow rate which were 57.8% and 55.6%, respectively. It was statistically higher with a dialysate flow at 1.5 times the blood flow (93.3%) compared to the dialysate flow at 500 mL / min (p = 0.036). The dialysate volume used with a dialysate flow rate of 500 mL / min was higher compared to the other dialysate flow rates (p = 0.0001). Conclusions: An adequate dialysis dose could be achieved with a dialysate flow rate of 1.5 times the blood flow rate, thereby saving significant amount of water.


2017 ◽  
Vol 32 (suppl_3) ◽  
pp. iii624-iii625
Author(s):  
Hicham Rafik ◽  
Taoufiq Aatif ◽  
Mounia Azizi ◽  
Majdouline Errihani ◽  
Aya Sobhi ◽  
...  

1992 ◽  
Vol 15 (8) ◽  
pp. 470-474 ◽  
Author(s):  
I.D. Daniels ◽  
G.M. Berlyne ◽  
R.H. Barth

We studied the effect of extracorporeal blood flow rate (BFR) on access recirculation (recirc) in 19 hemodialysis patients. BUN was determined in simultaneous peripheral (P), arterial (A), and venous (V) blood obtained at BFRs of 200, 400 and 600 ml/min. Percent recirc was calculated for each BFR using the formula (P-A) / (P-V) X 100. Venous drip-chamber (VP) and pre-blood-pump (AP) pressures were measured at each BFR. Fistulograms were performed in 10 patients, and stenoses were identified in 5, all at the proximal (arterial) end of the access. Recirc increased with increasing BFR from 200 to 400 ml/min but increased little from 400 to 600 ml/min. At all BFRs recirc in the stenotic patients was higher than that of non-stenotic or unstudied patients. Urea clearance, corrected for recirc, rose with blood flow both in stenotic and non-stenotic patients. There were no differences in AP or in VP between stenotic and non-stenotic patients. At BFR ≥ 400 ml/min, a recirc threshold of 15% identified stenoses with sensitivity 100% and specificity 71%. We conclude (1) recirc increases with increasing BFR but not enough to outweight the concomitant increase in urea clearance; (2) significant access stenosis and recirc may be present even with low VP; (3) recirc was associated with arterial side stenoses; (4) at BFR ≥ 400 ml/min, access stenosis is associated with recirc > 15%.


2001 ◽  
Vol 38 (5) ◽  
pp. 948-955 ◽  
Author(s):  
Daxenos R.M. Hassell ◽  
Frank M. van der Sande ◽  
Jeroen P. Kooman ◽  
Jan P. Tordoir ◽  
Karel M.L. Leunissen

2018 ◽  
Vol 110 (3) ◽  
pp. 270-275 ◽  
Author(s):  
Mansooreh Aliasgharpour ◽  
Soheila Zabolypour ◽  
Ahmadali Asadinoghabi ◽  
Hamid Haghani ◽  
Mahboub Lesanpezeshki

2020 ◽  
Author(s):  
Siyu Bai ◽  
Hong Li ◽  
Li Li

Abstract Hitherto, research on the fluid-structure coupling of coronary stents has mostly considered the state after stent expansion following implantation. However, the factors and how they affect stent expansion are as yet, unclear. To further investigate stent expansion, this paper proposes a model combining balloon, stent, and blood using Solidworks. Thereafter, a co-simulation using ANSYS Workbench is implemented using the methods of finite element and finite volume, to analyze bidirectional fluid-structure coupling during the expansion of a balloon-expandable stent, for periodically varying blood loads. By comparing the blood flow rate in the vessel, pressure on the endovascular wall, and the pressure and stress on the stent system at different points in time, it can be seen that the higher the blood flow rate, the greater the pressure on the endovascular wall and stent system. Furthermore, the larger the volume of the implant, the greater the maximum blood flow rate and maximum pressure on the endovascular wall, and the more drastic the change along the axis. In summary, the results of the present study indicate that the stent expansion process has a significant effect on the blood flow rate and pressure on the vascular wall; however, the impact of blood load on stent stress can be ignored.


1994 ◽  
Vol 23 (6) ◽  
pp. 846-848 ◽  
Author(s):  
Richard A. Sherman ◽  
James J. Matera ◽  
Laura Novik ◽  
Ronald P. Cody

2020 ◽  
Vol 12 (11) ◽  
pp. 106
Author(s):  
Nur Samsu ◽  
Fatmawati Fatmawati ◽  
Aurora Permatasari ◽  
Kartin Kartin ◽  
Wahyu Wulandari

BACKGROUND: Blood flow rate (BFR) and time of dialysis are important determinants of dialysis adequacy. This study aimed to determine the impact of higher BFR and longer dialysis time on nutritional status in chronic hemodialysis (HD) patients. METHODS: Real-world evidence (RWE) studies of 3 HD units in different hospitals that differ in BFR and/or dialysis time. Group I, HD 5 hr and BFR 200-250 mL/min; group II, HD 4 hr and BFR 270-320 mL/min, and group III, HD 4 hr and BFR 200-250 mL/min. All HD units use the same dialysate flow and dialysis frequency. Nutritional status was assessed using a 3-point scale Subjective Global Assessment. RESULTS: A total of 233 chronic HD patients were included, mean of age was 52 ± 12.9 years, 46.5% were male. There are 69.5% on SGA class A, 27.5% on SGA class B, and 3% on SGA class C. The proportion of SGA class A in group II was highest compared to group II and III (93.5% vs 79.0% vs 32.1% (p <0.05). There was no SGA class C in group II, whereas 2.4% in group I and 7.4% in group III. In group II there was lower interdialytic weight gain (IDWG) and less use of anti-hypertensive drugs compared to group III (p <0.05). CONCLUSION: Our study showed that higher BFR and longer dialysis time are associated with better nutritional status in chronic HD patients. A higher BFR seems to have a more substantial impact compared to a longer dialysis time. Keywords: blood flow rate, dialysis time, subjective global assessment, nutritional status


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