Association of polymorphism of DNA repair gene XRCC1 with sporadic late-onset Alzheimer's disease and age of onset in elderly Han Chinese

2010 ◽  
Vol 295 (1-2) ◽  
pp. 62-65 ◽  
Author(s):  
Yun Qian ◽  
Weixian Chen ◽  
Jianqing Wu ◽  
Tong Tao ◽  
Liqing Bi ◽  
...  
2007 ◽  
Vol 28 (1) ◽  
pp. 31-34 ◽  
Author(s):  
S. Doğru-Abbasoğlu ◽  
G. Aykaç-Toker ◽  
H. A. Hanagasi ◽  
H. Gürvit ◽  
M. Emre ◽  
...  

2019 ◽  
Vol 709 ◽  
pp. 134362 ◽  
Author(s):  
Yıldız Dinçer ◽  
Çağlayan Akkaya ◽  
Tuba Mutlu ◽  
Serap Yavuzer ◽  
Gökhan Erkol ◽  
...  

2007 ◽  
Vol 414 (3) ◽  
pp. 282-285 ◽  
Author(s):  
Fabio Coppedè ◽  
Michelangelo Mancuso ◽  
Annalisa Lo Gerfo ◽  
Maria Laura Manca ◽  
Lucia Petrozzi ◽  
...  

2013 ◽  
Vol 15 (2) ◽  
pp. 279-287 ◽  
Author(s):  
Xiao-Ying Ma ◽  
Jin-Tai Yu ◽  
Wei Wang ◽  
Hui-Fu Wang ◽  
Qiu-Yan Liu ◽  
...  

2006 ◽  
Vol 404 (3) ◽  
pp. 258-261 ◽  
Author(s):  
Semra Dogru-Abbasoglu ◽  
Muzeyyen Inceoglu ◽  
Hande Parildar-Karpuzoglu ◽  
Hasmet A. Hanagasi ◽  
Berrin Karadag ◽  
...  

2014 ◽  
Vol 52 ◽  
pp. 18-22 ◽  
Author(s):  
Jun Wang ◽  
Jin-Tai Yu ◽  
Teng Jiang ◽  
Meng-Shan Tan ◽  
Hui-Fu Wang ◽  
...  

2012 ◽  
Vol 9 (5) ◽  
pp. 546-553 ◽  
Author(s):  
Lan Tan ◽  
Jin-Tai Yu ◽  
Wei Zhang ◽  
Zhong-Chen Wu ◽  
Qun Zhang ◽  
...  

2016 ◽  
Vol 13 (3) ◽  
pp. 239-243 ◽  
Author(s):  
Huan Lu ◽  
Xi-Chen Zhu ◽  
Hui-Fu Wang ◽  
Lei Cao ◽  
Meng-Shan Tan ◽  
...  

Author(s):  
Ratnavalli Ellajosyula

The term ‘early onset Alzheimer’s disease’ (EOAD) is used when symptoms of Alzheimer’s disease (AD) occur in patients younger than 65 years. EOAD is an uncommon condition and data on epidemiology is limited. Prevalence rates range from 15 to 200 and incidence rates 2.4–22.6 per 100,000 population. Prevalence rates increase with age similar to that for late onset AD. The prevalence of autosomal dominant EOAD is 5.2 per 100,000. Half of these patients have an underlying mutation in amyloid precursor protein, presenilin 1 or 2 genes. Apolipoprotein E genotype is a risk factor for EOAD and homozygotes have an earlier age of onset. Methodological issues and geographical location make comparisons across epidemiological studies difficult. Further cross-national and cross-cultural studies with standardized methodology are necessary to understand the role of risk and protective factors, as well as to estimate the burden of the disease.


Sign in / Sign up

Export Citation Format

Share Document