Narrowband UVB phototherapy for clinically isolated syndrome: Delivering the benefits of all UVB-induced molecules

2017 ◽  
Vol 381 ◽  
pp. 446
Author(s):  
A.G. Kermode ◽  
P. Hart ◽  
R. Lucas ◽  
D. Booth ◽  
W. Carroll ◽  
...  
Keyword(s):  
Clinically Isolated Syndrome ◽  
Narrowband Uvb ◽  
Uvb Phototherapy

scholarly journals Narrowband UVB Phototherapy for Clinically Isolated Syndrome: A Trial to Deliver the Benefits of Vitamin D and Other UVB-Induced Molecules

2017 ◽  
Vol 8 ◽  
Author(s):  
Prue H. Hart ◽  
Robyn M. Lucas ◽  
David R. Booth ◽  
William M. Carroll ◽  
David Nolan ◽  
...  
Keyword(s):  
Vitamin D ◽  
Clinically Isolated Syndrome ◽  
Narrowband Uvb ◽  
Uvb Phototherapy

scholarly journals Short-term changes in frequencies of circulating leukocytes associated with narrowband UVB phototherapy in people with clinically isolated syndrome

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Stephanie Trend ◽  
Anderson P. Jones ◽  
Lilian Cha ◽  
Matthew N. Cooper ◽  
Sian Geldenhuys ◽  
...  
Keyword(s):  
Clinically Isolated Syndrome ◽  
Short Term ◽  
Narrowband Uvb ◽  
Uvb Phototherapy

scholarly journals A randomised, controlled clinical trial of narrowband UVB phototherapy for clinically isolated syndrome: The PhoCIS study

2018 ◽  
Vol 4 (2) ◽  
pp. 205521731877311 ◽  
Author(s):  
Prue H Hart ◽  
Anderson P Jones ◽  
Stephanie Trend ◽  
Lilian Cha ◽  
Marzena J Fabis-Pedrini ◽  
...  
Keyword(s):  
Clinically Isolated Syndrome ◽  
Controlled Clinical Trial ◽  
Therapeutic Effects ◽  
Uvb Radiation ◽  
Hydroxyvitamin D ◽  
Narrowband Uvb ◽  
History Of ◽  
Uvb Exposure ◽  
Randomised Controlled ◽  
Uvb Phototherapy

Background The natural history of multiple sclerosis (MS) typically presents with the clinically isolated syndrome (CIS), an episode of neurological symptoms caused by central nervous system inflammation or demyelination that does not fulfil the diagnostic criteria for MS. Objective As preclinical studies have suggested that exposure to ultraviolet radiation (UVR) could regulate the development of MS, the Phototherapy for CIS (PhoCIS trial) was established to examine the effects of narrowband UVB phototherapy on patients with CIS, and their conversion to MS. Methods Of the 20 participants, half received 24 sessions of narrowband UVB exposure over eight weeks; participants in both arms were followed for 12 months. All participants were supplemented to 25-hydroxyvitamin D3 levels of >80 nmol/l. Results By 12 months, 100% of those in the no phototherapy arm and 70% in the phototherapy arm had converted to MS, although this difference was not statistically significant. Conclusion This study provides a basis for further studies to determine if there are any benefits of the therapeutic effects of narrowband UVB radiation on MS progression.

Cutaneous carcinogenic risk evaluation in 375 patients treated with narrowband-UVB phototherapy

2018 ◽  
Vol 34 (5) ◽  
pp. 302-306 ◽  
Author(s):  
Beatrice Raone ◽  
Annalisa Patrizi ◽  
Carlotta Gurioli ◽  
Andrea Gazzola ◽  
Giulia Maria Ravaioli
Keyword(s):  
Risk Evaluation ◽  
Carcinogenic Risk ◽  
Narrowband Uvb ◽  
Uvb Phototherapy
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