scholarly journals Anti-musk antibody myasthenia gravis: Clinical findings and long term follow up

2019 ◽  
Vol 405 ◽  
pp. 246
Author(s):  
R. Kulkarni ◽  
S. Pujari
2015 ◽  
Vol 2 (1) ◽  
pp. 37-40
Author(s):  
Yacouba Njankouo Mapoure ◽  
◽  
Namme Henry Luma ◽  
Cyrille Nkouonlack ◽  
Ariane Vanessa Pokossy ◽  
...  

2017 ◽  
Vol 102 (6) ◽  
pp. 757-760 ◽  
Author(s):  
Amir Sternfeld ◽  
Daniella Lobel ◽  
Hana Leiba ◽  
Judith Luckman ◽  
Shalom Michowiz ◽  
...  

Background/AimsBenign positional vertical opsoclonus in infants, also described as paroxysmal tonic downgaze, is an unsettling phenomenon that leads to extensive work-up, although benign course has been reported in sporadic cases. We describe long-term follow-up of a series of infants with the phenomenon.MethodsThis retrospective cohort included all infants diagnosed with rapid downgaze eye movement in 2012–2015 and followed until 2016. The databases of two medical centres were retrospectively reviewed. Benign positional vertical opsoclonus was diagnosed based on clinical findings of experienced neuro-ophthalmologists. Data were collected on demographics, symptoms and signs, neuro-ophthalmological and neurological evaluations, and outcome. Imaging studies were reviewed. Main outcome measures were long-term outcome and findings of the thorough investigation.ResultsThe cohort included six infants. All infants were born at term. Age at presentation was several days to 12 weeks. Episodes lasted a few seconds and varied in frequency from <10 to dozens per day. In five infants, symptoms occurred in the supine position. There was a wide variability in the work-up without any pathological findings. Follow-up ranged from 1 to 2.5 years. Ocular symptoms gradually decreased until resolution. Infants reached normal developmental milestones.ConclusionsOur identification of six patients in only 3 years suggests benign positional vertical opsoclonus may be more prevalent than previously described. In our experience, it affects otherwise healthy infants and resolves spontaneously. In view of the good long-term outcome, a comprehensive clinical investigation may not be necessary.


2019 ◽  
Vol 20 (2) ◽  
pp. 51-54
Author(s):  
Sadia Armin Khan ◽  
Abu Ahmed Ashraf Ali

Background: Granulomatous mastitis also known as granulomatous inflammatory lesionsof the breast can be divided into idiopathic granulomatous mastitis and granulomatousmastitis occurring as a rare secondary complication of a great variety of other conditions.Treatment is radically different for idiopathic granulomatous mastitis and other granulomatouslesions of the breast, the precise diagnosis is therefore very important. Objectives: The purpose of this study was to find the clinicopathological features ofidiopathic granulomatous mastitis, as well as the authors' experience with surgicaltreatment of these patients. Methods and Materials: A hospital based retrospective study done with twenty diagnosedpatients of idiopathic granulomatous mastitis enrolled from department of surgery, Ad-dinwomen's.medical college hospital, Dhaka in the period between July 2012- July 2015. Results: Mean age of presentation was 38.1 years. All patients had a history of childbirthand breastfeeding. Sixteen (80%) patients were premenopausal. The main clinical featurewas a mass in the breast in all patients and clinical findings suggesting an infection accompaniedthe mass in seven patients (35%). Surgery was the definitive procedure in allpatients. Wide local excision done in all patients. None of the patients received steroids.Median follow-up time was 12 months. During follow-up, two patients (10%) presented withrecurrence. All patients with recurrence had a mass in their breasts on the same side ofprevious disease. Conclusion: Increased recognition of this disease will improve its understanding andmanagement. Long-term follow-up is necessary. Journal of Surgical Sciences (2016) Vol. 20 (2) :51-54


2014 ◽  
Vol 4 (2) ◽  
pp. 134-135
Author(s):  
Tumay Ipekci ◽  
Yigit Akin ◽  
Burak Hoscan ◽  
Ahmet Tunckiran

Testicular neoplasm usually occur in men aged between 15 and 35. These are solid organ tumours and also should be operated when there is a suspicious clinical findings. Testis tumours are levelled after histopathology evaluation. The medical, surgical and follow-up strategies of well know testis tumours, such as seminomas, non-seminom germ cell tumours, have been established. In case of testis tumours rare entities may occur as rhabdomyosarcoma.We here presented a rare case of   alveolar subtype of rhabdomyosarcoma in testis with long term follow-up.


2013 ◽  
Vol 71 (7) ◽  
pp. 462-464 ◽  
Author(s):  
Paulo José Lorenzoni ◽  
Lucas Pires Augusto ◽  
Cláudia Suemi Kamoi Kay ◽  
Rosana Herminia Scola ◽  
Lineu Cesar Werneck

Thymoma screening is recommended at the onset of myasthenia gravis (MG) or when patients with MG present with clinical deterioration or a progressive increase of anti-acetylcholine receptor antibody. However, it is unknown if it is necessary to repeat the screening of thymoma at fixed intervals, even in the absence of MG deterioration, when the initial screening is negative. We analyzed the recurrence rate and incidence of new thymoma in a series of patients with well-controlled MG. The sample consisted of 53 patients, aged 17 to 72 years, and the follow-up varied between 75 and 472 months. The chest computerized tomography detected thymus abnormalities in eight patients at the initial screening and no abnormalities in all patients at a second screening after five years. The findings of this study support the classical opinion that screening for thymoma should be recommended only if there is clinical deterioration due to the disease.


2011 ◽  
Vol 92 (3) ◽  
pp. 1018-1023 ◽  
Author(s):  
Richard K. Freeman ◽  
Anthony J. Ascioti ◽  
Jaclyn M. Van Woerkom ◽  
Amy Vyverberg ◽  
Robert J. Robison

2012 ◽  
Vol 51 (21) ◽  
pp. 3077-3079 ◽  
Author(s):  
Ai Hosaka ◽  
Hiroshi Takuma ◽  
Kiyoe Ohta ◽  
Akira Tamaoka

2013 ◽  
Vol 33 (1) ◽  
pp. 40-44 ◽  
Author(s):  
Jason H. Peragallo ◽  
Federico G. Velez ◽  
Joseph L. Demer ◽  
Stacy L. Pineles

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