scholarly journals Neurophysiologic assessment of sensory denervation in chemotherapy induced polyneuropathy

2019 ◽  
Vol 405 ◽  
pp. 131
Author(s):  
B. Isak ◽  
H. Tankisi ◽  
K. Pugdahl ◽  
L. Ventzel ◽  
A. Nanna Brix Frederiksen ◽  
...  
Keyword(s):  
Pain Medicine ◽  
2019 ◽  
Vol 20 (11) ◽  
pp. 2208-2212 ◽  
Author(s):  
Aaron Conger ◽  
Daniel M Cushman ◽  
Kortnie Walker ◽  
Russell Petersen ◽  
David R Walega ◽  
...  

Abstract Background Fluoroscopically guided cooled genicular nerve radiofrequency ablation (RFA) is an increasingly performed procedure for chronic, refractory knee pain due to osteoarthritis. Traditionally, partial sensory denervation has been accomplished through ablation of the superomedial, superolateral, and inferomedial genicular nerves. However, recent cadaveric studies have demonstrated additional sensory nerves and significant anatomic variation that impact current protocols. Objective We describe an updated cooled genicular nerve radiofrequency ablation protocol that accounts for varied nerve location of the superomedial, superolateral, and inferomedial genicular nerves, as well as capture of the terminal articular branches of the nerves to the vastus intermedius, vastus lateralis, and vastus medialis. Furthermore, we describe an adjusted technique for inferomedial genicular nerve capture that mitigates the risk of pes anserine tendon injury. Design Technical report and brief literature review. Methods Cadaveric studies relating to the sensory innervation of the anterior knee joint were reviewed, and a more accurate and comprehensive cooled genicular nerve radiofrequency ablation (CRFA) protocol is proposed. Conclusions Based on recent, rigorous anatomic dissections of the knee, the proposed genicular nerve CRFA protocol will provide more complete sensory denervation and potentially improve clinical outcomes. Prospective studies will be needed to confirm the hypothesis that this protocol will result in improved effectiveness and safety of genicular nerve RFA.


1995 ◽  
Vol 268 (2) ◽  
pp. G200-G206
Author(s):  
Y. Hatakeyama ◽  
M. Matsuo ◽  
M. Tomoi ◽  
M. Ohtsuka ◽  
K. Shimomura

We have recently shown that certain mild irritants caused the increase in fluid volume in the rat stomach. The present study was conducted to investigate 1) whether standing fluid in the gastric cavity can prevent gastric mucosal injury caused by 0.6 N HCl and 2) the mechanisms by which certain mild irritants increase the gastric fluid volume. One milliliter of water administered immediately before irritants greatly inhibited gastric lesion formation. Sodium chloride and capsaicin induced a profound enhancement of gastric fluid volume, as acid mild irritants did also. Sensory denervation completely abolished the volume increase caused by capsaicin but hardly influenced that caused by mild irritants. Capsaicin increased the amount of Evans blue in the gastric fluid, but mild irritants did not. On the other hand, HCl and capsaicin significantly inhibited the emptying of phenol red. From these results, we conclude that mild irritants and capsaicin can induce volume increase that by itself is enough to afford protection through luminal dilution. Capsaicin but not mild irritants requires sensory neurons to increase the gastric fluid volume. Certain mild irritants may provide a fluid pooling effect partly by inhibiting gastric emptying.


2007 ◽  
Vol 40 (3) ◽  
pp. 141-149 ◽  
Author(s):  
Tsukasa Ikeura ◽  
Yosky Kataoka ◽  
Taketoshi Wakabayashi ◽  
Tetsuji Mori ◽  
Yasuharu Takamori ◽  
...  

1983 ◽  
Vol 288 (1-2) ◽  
pp. 77-83 ◽  
Author(s):  
Claire E. Hulsebosch ◽  
Richard E. Coggeshall

2009 ◽  
Vol 91 (12) ◽  
pp. 2886-2895 ◽  
Author(s):  
Peter J Apel ◽  
Daniel Crane ◽  
Casey N Northam ◽  
Michael Callahan ◽  
Thomas L Smith ◽  
...  

2012 ◽  
Vol 53 (13) ◽  
pp. 8280 ◽  
Author(s):  
Alessandro Lambiase ◽  
Luigi Aloe ◽  
Flavio Mantelli ◽  
Marta Sacchetti ◽  
Eleonora Perrella ◽  
...  

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