scholarly journals Eicosapentaenoic acid regulates brown adipose tissue metabolism in high-fat-fed mice and in clonal brown adipocytes

2017 ◽  
Vol 39 ◽  
pp. 101-109 ◽  
Author(s):  
Mandana Pahlavani ◽  
Fitia Razafimanjato ◽  
Latha Ramalingam ◽  
Nishan S. Kalupahana ◽  
Hanna Moussa ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Eicosapentaenoic Acid ◽  
Brown Adipose Tissue ◽  
High Fat ◽  
Brown Adipocytes ◽  
Adipose Tissue Metabolism ◽  
Tissue Metabolism ◽  
Brown Adipose

Brown adipose tissue metabolism in ob/ob mice: effects of a high-fat diet and adrenalectomy

1987 ◽  
Vol 253 (2) ◽  
pp. E149-E157
Author(s):  
H. K. Kim ◽  
D. R. Romsos
Keyword(s):  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
High Fat Diet ◽  
High Fat ◽  
Adipose Tissue Metabolism ◽  
High Carbohydrate ◽  
Bat Mitochondria ◽  
Norepinephrine Turnover ◽  
Brown Adipose ◽  
Thermogenic Capacity

Adrenalectomy prevents development of obesity in ob/ob mice fed high-carbohydrate stock diets partly by stimulating the low thermogenic capacity of their brown adipose tissue (BAT). Adrenalectomy, however, fails to prevent development of obesity in ob/ob mice fed a high-fat diet. Effects of adrenalectomy on BAT metabolism in ob/ob mice fed a high-fat diet were thus examined. ob/ob mice fed the high-fat diet developed gross obesity despite normal BAT metabolism, as assessed by rates of norepinephrine turnover in BAT, GDP binding to BAT mitochondria, and GDP-inhibitable, chloride-induced mitochondrial swelling. Adrenalectomy failed to arrest the development of obesity or to influence BAT metabolism in ob/ob mice fed the high-fat diet. Development of obesity in ob/ob mice fed a high-fat diet is not associated with low thermogenic capacity of BAT or with adrenal secretions, as it is in ob/ob mice fed high-carbohydrate stock diets.

Effects of stanniocalcin hormones on rat brown adipose tissue metabolism under fed and fasted conditions

2019 ◽  
Vol 485 ◽  
pp. 81-87 ◽  
Author(s):  
Elaine Sarapio ◽  
Samir Khal Souza ◽  
Everton Lopes Vogt ◽  
Débora Santos Rocha ◽  
Rafael Bandeira Fabres ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Adipose Tissue Metabolism ◽  
Tissue Metabolism ◽  
Brown Adipose

scholarly journals Eicosapentaenoic acid regulates brown adipose tissue gene expression and metabolism in high fat fed mice (1037.5)

2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
Mandanna Pahlavani ◽  
Nishan Kalupahana ◽  
Monique LeMieux ◽  
Arwa Aljawadi ◽  
Shane Scoggin ◽  
...  
Keyword(s):  
Gene Expression ◽  
Adipose Tissue ◽  
Eicosapentaenoic Acid ◽  
Brown Adipose Tissue ◽  
High Fat ◽  
Brown Adipose ◽  
Adipose Tissue Gene Expression ◽  
Tissue Gene Expression

Endocrine Mechanisms Connecting Exercise to Brown Adipose Tissue Metabolism: a Human Perspective

2020 ◽  
Vol 20 (9) ◽  
Author(s):  
Andrea Mendez-Gutierrez ◽  
Francisco J. Osuna-Prieto ◽  
Concepcion M Aguilera ◽  
Jonatan R Ruiz ◽  
Guillermo Sanchez-Delgado
Keyword(s):  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Adipose Tissue Metabolism ◽  
Tissue Metabolism ◽  
Brown Adipose

A critical appraisal of brown adipose tissue metabolism in humans

2015 ◽  
Vol 10 (3) ◽  
pp. 259-280 ◽  
Author(s):  
Denis P Blondin ◽  
Sébastien M Labbé ◽  
Eric E Turcotte ◽  
François Haman ◽  
Denis Richard ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Critical Appraisal ◽  
Adipose Tissue Metabolism ◽  
Tissue Metabolism ◽  
Brown Adipose

Uncoupling protein 1 expression and high-fat diets

2011 ◽  
Vol 300 (1) ◽  
pp. R1-R8 ◽  
Author(s):  
Tobias Fromme ◽  
Martin Klingenspor
Keyword(s):  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Uncoupling Protein ◽  
Caloric Intake ◽  
High Fat ◽  
Uncoupling Protein 1 ◽  
Brown Adipocytes ◽  
Adaptive Thermogenesis ◽  
Brown Adipose ◽  
Thermoregulatory Function

Uncoupling protein 1 (Ucp1) is the key component of β-adrenergically controlled nonshivering thermogenesis in brown adipocytes. This process combusts stored and nutrient energy as heat. Cold exposure not only activates Ucp1-mediated thermogenesis to maintain normothermia but also results in adaptive thermogenesis, i.e., the recruitment of thermogenic capacity in brown adipose tissue. As a hallmark of adaptive thermogenesis, Ucp1 synthesis is increased proportionally to temperature and duration of exposure. Beyond this classical thermoregulatory function, it has been suggested that Ucp1-mediated thermogenesis can also be employed for metabolic thermogenesis to prevent the development of obesity. Accordingly, in times of excess caloric intake, one may expect a positive regulation of Ucp1. The general impression from an overview of the present literature is, indeed, an increased brown adipose tissue Ucp1 mRNA and protein content after feeding a high-fat diet (HFD) to mice and rats. The reported increases are very variable in magnitude, and the effect size seems to be independent of dietary fat content and duration of the feeding trial. In white adipose tissue depots Ucp1 mRNA is generally downregulated by HFD, indicating a decline in the number of interspersed brown adipocytes.

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