Fibroblasts and macrophages: Key players in the head and neck cancer microenvironment

2017 ◽  
Vol 59 (1) ◽  
pp. 23-30 ◽  
Author(s):  
Kusumawadee Utispan ◽  
Sittichai Koontongkaew
2021 ◽  
Vol 22 (20) ◽  
pp. 11027
Author(s):  
Michal Španko ◽  
Karolína Strnadová ◽  
Aleš Jan Pavlíček ◽  
Pavol Szabo ◽  
Ondřej Kodet ◽  
...  

Interleukin-6 (IL-6) is a highly potent cytokine involved in multiple biological processes. It was previously reported to play a distinct role in inflammation, autoimmune and psychiatric disorders, ageing and various types of cancer. Furthermore, it is understood that IL-6 and its signaling pathways are substantial players in orchestrating the cancer microenvironment. Thus, they appear to be potential targets in anti-tumor therapy. The aim of this article is to elucidate the role of IL-6 in the tumor ecosystem and to review the possible therapeutic approaches in head and neck cancer.


2021 ◽  
Vol 144 ◽  
pp. 112269
Author(s):  
Marcelo Coutinho de Miranda ◽  
Mariane Izabella Abreu de Melo ◽  
Pricila da Silva Cunha ◽  
Jovino Gentilini ◽  
Jerusa Araújo Quintão Arantes Faria ◽  
...  

1998 ◽  
Vol 23 (4) ◽  
pp. 376-376
Author(s):  
Quak ◽  
Van Bokhorst ◽  
Klop ◽  
Van Leeuwen ◽  
Snow

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