Evaluating the Transvaginal Ultrasound Diagnostic Criteria for Abnormal First-Trimester Pregnancy With Follow-Up Into the Third Trimester and Validation of Results

2021 ◽  
Author(s):  
Jamil A.K. Addas ◽  
Abdullah Alabousi ◽  
Khaled Almohaimede ◽  
Peri Abdullah ◽  
Mostafa Atri
Keyword(s):  
Diagnostic Criteria ◽  
Transvaginal Ultrasound ◽  
First Trimester ◽  
Third Trimester ◽  
The Third ◽  
First Trimester Pregnancy ◽  
Trimester Pregnancy ◽  
Validation Of Results

Emergency Department Patient Perceptions of Transvaginal Ultrasound for Complications of First-Trimester Pregnancy

2018 ◽  
Vol 37 (8) ◽  
pp. 1965-1975 ◽  
Author(s):  
Nova Panebianco ◽  
Frances Shofer ◽  
Katie O'Conor ◽  
Tristan Wihbey ◽  
Lakeisha Mulugeta ◽  
...  
Keyword(s):  
Emergency Department ◽  
Transvaginal Ultrasound ◽  
Emergency Department Patient ◽  
First Trimester ◽  
Patient Perceptions ◽  
First Trimester Pregnancy ◽  
Trimester Pregnancy

Sequelae of Congenital Cytomegalovirus Following Maternal Primary Infections Are Limited to Those Acquired in the First Trimester of Pregnancy

2018 ◽  
Vol 69 (9) ◽  
pp. 1526-1532 ◽  
Author(s):  
Valentine Faure-Bardon ◽  
Jean-François Magny ◽  
Marine Parodi ◽  
Sophie Couderc ◽  
Patricia Garcia ◽  
...  
Keyword(s):  
Primary Infection ◽  
Accurate Determination ◽  
First Trimester ◽  
Maternal Infection ◽  
Third Trimester ◽  
The Third ◽  
Neurologic Sequelae ◽  
Early Fetal Period ◽  
Case Outcome

Abstract Background The known relationship between the gestational age at maternal primary infection an the outcome of congenital CMV is based on small, retrospective studies conducted between 1980 and 2011. They reported that 32% and 15% of cases had sequelae following a maternal primary infection in the first and second or the third trimester, respectively. We aimed to revisit this relationship prospectively between 2011 and 2017, using accurate virological tools. Methods We collected data on women with a primary infection and an infected child aged at least 1 year at the time of analysis. An accurate determination of the timing of the primary infection was based upon serial measurements of immunoglobulin (Ig) M and IgG and on IgG avidity in sera collected at each trimester. The case outcome was assessed according to a structured follow-up between birth and 48 months. Results We included 255 women and their 260 fetuses/neonates. The dating of the maternal infection was prospective in 86% of cases and retrospective in 14%. At a median follow-up of 24 months, the proportion of sensorineural hearing loss and/or neurologic sequelae were 32.4% (95% confidence interval [CI] 23.72–42.09) after a maternal primary infection in the first trimester, 0 (95% CI 0–6.49) after an infection in the second trimester, and 0 (95% CI 0–11.95) after an infection in the third trimester (P < .0001). Conclusions These results suggest that a cytomegalovirus infection can be severe only when the virus hits the fetus in the embryonic or early fetal period. Recent guidelines recommend auditory follow-ups for at least 5 years for all infected children. This raises parental anxiety and generates significant costs. We suggest that auditory and specialized neurologic follow-ups may be recommended only in cases of a maternal infection in the first trimester.

The utility of transvaginal ultrasound in the ED evaluation of complications of first trimester pregnancy

2015 ◽  
Vol 33 (6) ◽  
pp. 743-748 ◽  
Author(s):  
Nova L. Panebianco ◽  
Frances Shofer ◽  
J. Matthew Fields ◽  
Kenton Anderson ◽  
Alessandro Mangili ◽  
...  
Keyword(s):  
Transvaginal Ultrasound ◽  
First Trimester ◽  
First Trimester Pregnancy ◽  
Trimester Pregnancy

scholarly journals Omphalocele Secondary to Spontaneous Rupture of Allantoic Cyst in the Third Trimester of Pregnancy

2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Giuliana Orlandi ◽  
Paolo Toscano ◽  
Lavinia Di Meglio ◽  
Letizia Di Meglio ◽  
Aniello Di Meglio
Keyword(s):  
Spontaneous Rupture ◽  
Pediatric Surgery ◽  
First Trimester ◽  
Causal Link ◽  
Third Trimester ◽  
Case Presentation ◽  
The Third ◽  
Urgent Surgery ◽  
First Case

Objective. We report the first case in which the onset of omphalocele was after the spontaneous rupture of an allantoic cyst. We hypothesize a causal link between the spontaneous rupture of the cyst and the herniation of the viscera. Case Presentation. A 36-year-old woman was diagnosed with an allantoic cyst during the first trimester. The allantoic cyst underwent spontaneous rupture during the 32nd week of gestation, and an omphalocele developed secondary to the cyst’s rupture. Two days after birth, the peritoneum covering intestinal loops broke spontaneously and the newborn underwent successful urgent surgery. Conclusions. This case may suggest that the relative benignity of the allantoid cysts may recommend a close ultrasound follow-up in order to identify the onset of any complications, as a late third trimester onset of omphalocele. Prenatal diagnosis of such complications may allow multidisciplinary management of the pregnancy with planned cesarean section, prenatal pediatric surgery consultation, and neonatal surgery.

scholarly journals Smith–Lemli–Opitz's Syndrome as a Possible Cause of Recurrent Pregnancy Loss: A Case Report

2020 ◽  
Vol 10 (01) ◽  
pp. e118-e120 ◽  
Author(s):  
Anjali Mitra ◽  
Shelley Dolitsky ◽  
Stacy Yadava ◽  
Elena Ashkinadze
Keyword(s):  
Pregnancy Loss ◽  
Dna Analysis ◽  
Recurrent Pregnancy Loss ◽  
First Trimester ◽  
Carrier Screening ◽  
The Third ◽  
First Trimester Pregnancy ◽  
Trimester Pregnancy ◽  
Work Up ◽  
Possible Cause

AbstractBased on the known carrier frequency of Smith–Lemli–Opitz's syndrome (SLOS), the prevalence of this disease should be significantly higher than what is observed in the population. This may be due to a higher rate of pregnancy loss in affected embryos. Here, we present the case of a couple who underwent expanded carrier screening (ECS) after experiencing three first trimester pregnancy losses. Both parents were found to be carriers of SLOS mutations, and DNA analysis of the fetal remains of the third loss revealed the aborted fetus had inherited both the maternal and paternal mutations. This suggests SLOS as a reason for this patient's recurrent pregnancy loss (RPL), and therefore, ECS should be considered as part of the RPL work-up.

scholarly journals Is There an Association Between Early Pregnancy Losses and Low 25-Hydroxy Vitamin D Levels?

2017 ◽  
Vol 1 (1) ◽  
pp. 1-5
Author(s):  
Lebriz Hale Aktun ◽  
Yeliz Aykanat ◽  
Oktay Olmuscelik
Keyword(s):  
Vitamin D ◽  
Early Pregnancy ◽  
Pregnancy Loss ◽  
First Trimester ◽  
Normal Pregnancy ◽  
First Trimester Pregnancy ◽  
Pregnancy History ◽  
Trimester Pregnancy ◽  
25 Hydroxy Vitamin D

Objective: Since the etiology of pregnancy losses during first trimester has not still been clear, we aim to analyze the relationship between vitamin D deficiency and early pregnancy losses. Patients and Methods: The study was conducted on 200 women. Plasma was collected from 100 nulliparous women with singleton at 7-10 weeks of gestation (50 with viable gestation and 50 with pregnancy loss) and 100 non-gravid reproductive age women (50 with a successful pregnancy history and 50 with one or more spontaneous first trimester pregnancy loss history). Serum 25 (OH) D and calcium levels were compared between groups. Results: The serum 25(OH) D levels for the groups turned out to be 47.64 ± 3.2 (95% CI: 44.4-50.8 ng/ml) for normal pregnancy group, 27.3 ± 1.2 (95% CI: 26.1-28.5 ng/ml) for the group of early pregnancy loss, 38.5 ± 5.1 (95% CI: 33.4-43.6 ng/ml) for the non gravid women with healthy pregnancy history and 11.6 ± 4.2 (95% CI: 7.9 - 15.6 ng/ml) for the non-gravid women with history of 1 or more first trimester pregnancy loss. There was a strong correlation between low 25(OH) D levels and early pregnancy loss (odds ratio (OR): 1.70, 95% CI: 1.2-2.3, p <0.001). The calcium levels were significantly lower in pregnancy loss group than normal pregnancy and non-gravid groups (p=0.005, p=0.033 respectively). Conclusions: Although our study is emphasized on role of vitamin D in early pregnancy it is not possible to recommend screening and supplementation of vitamin D in early pregnancy, as prognosis of pregnancies receiving supplementation and the incidence of pregnancy related complications in follow-up are not known. Well designed studies with long term follow up results needed. Keywords: 25 hydroxy vitamin D, Pregnancy loss, 25 (OH) D vitamin

Sign in / Sign up

Export Citation Format

Share Document