scholarly journals Identifying Late-Stage Cancer and Chronic Kidney Disease Patients for Palliative Care Research and Practice: Computable Phenotypes and Natural Language Processing (S824)

2019 ◽  
Vol 57 (2) ◽  
pp. 494-495
Author(s):  
Natalie Ernecoff ◽  
Kathryn Wessell ◽  
Laura Hanson ◽  
Adam Lee ◽  
Stacie Dusetzina ◽  
...  
2017 ◽  
Vol 35 (31_suppl) ◽  
pp. 7-7
Author(s):  
Charlotta Lindvall ◽  
Elizabeth J. Lilley ◽  
Zara Cooper ◽  
Alexander W. Forsyth ◽  
Regina Barzilay ◽  
...  

7 Background: Natural Language Processing (NLP) presents a novel method of extracting text-embedded information from the electronic health record (EHR) to improve routine assessment of palliative quality metrics such as timely advance care planning (ACP), palliative care provision (PC), and hospice referral. Methods: We identified cancer patients (ICD-9-CM codes 140-209) who received a gastrostomy tube (ICD-9-CM 43.11, 43.19, 44.32; CPT code 49440) from Jan 1, 2012, to Mar 31, 2016 at an academic medical center. We used NLP to identify palliative indication for gastrostomy tube placement by labeling clinical notes from the EHR containing the key word “venting” near the time of the procedure. Documentation of ACP, PC, and hospice referral was identified by NLP using a validated key term library. The sensitivity and specificity of the NLP method was determined by comparing outcome identification to manual chart abstraction performed by two clinicians. All NLP code was written in the open-source programming language Python. Results: NLP was performed for 75,626 documents. Among 305 cancer patients who underwent gastrostomy, 75 (24.6%) were classified by NLP as having a palliative indication for the procedure compared to 72 patients (23.6%) classified by human coders. Manual chart abstraction took > 2,600 times longer than NLP (28 hrs vs. 38 seconds). NLP identified the correct patients with high precision (0.92) and recall (0.96). ACP was documented during the index admission for 89.3% of patients. PC was documented for 85.7% and hospice referral was documented for 64.3% of these patients with advanced cancer during the index hospitalization. NLP identified ACP, PC and hospice referral with high precision (0.88-1.0) and recall (0.92-1.0) compared to human coders. Median survival was 37 days following gastrostomy tube procedure. Conclusions: NLP can greatly speed the assessment of established palliative quality metrics with an accuracy approaching that of human coders. These methods offer opportunities for facilitate quality improvement in palliative care for patients with advanced cancer.


2020 ◽  
Vol 103 (4) ◽  
pp. 826-832
Author(s):  
Lindsay Ross ◽  
Christopher M. Danforth ◽  
Margaret J. Eppstein ◽  
Laurence A. Clarfeld ◽  
Brigitte N. Durieux ◽  
...  

2018 ◽  
Vol 55 (4) ◽  
pp. 1152-1158.e1 ◽  
Author(s):  
Natalie C. Ernecoff ◽  
Kathryn L. Wessell ◽  
Stacey Gabriel ◽  
Timothy S. Carey ◽  
Laura C. Hanson

2020 ◽  
Vol 59 (2) ◽  
pp. 225-232.e2 ◽  
Author(s):  
Katherine C. Lee ◽  
Brooks V. Udelsman ◽  
Jocelyn Streid ◽  
David C. Chang ◽  
Ali Salim ◽  
...  

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Eline van den Broek-Altenburg ◽  
Robert Gramling ◽  
Kelly Gothard ◽  
Maarten Kroesen ◽  
Caspar Chorus

Abstract Background High quality serious illness communication requires good understanding of patients’ values and beliefs for their treatment at end of life. Natural Language Processing (NLP) offers a reliable and scalable method for measuring and analyzing value- and belief-related features of conversations in the natural clinical setting. We use a validated NLP corpus and a series of statistical analyses to capture and explain conversation features that characterize the complex domain of moral values and beliefs. The objective of this study was to examine the frequency, distribution and clustering of morality lexicon expressed by patients during palliative care consultation using the Moral Foundations NLP Dictionary. Methods We used text data from 231 audio-recorded and transcribed inpatient PC consultations and data from baseline and follow-up patient questionnaires at two large academic medical centers in the United States. With these data, we identified different moral expressions in patients using text mining techniques. We used latent class analysis to explore if there were qualitatively different underlying patterns in the PC patient population. We used Poisson regressions to analyze if individual patient characteristics, EOL preferences, religion and spiritual beliefs were associated with use of moral terminology. Results We found two latent classes: a class in which patients did not use many expressions of morality in their PC consultations and one in which patients did. Age, race (white), education, spiritual needs, and whether a patient was affiliated with Christianity or another religion were all associated with membership of the first class. Gender, financial security and preference for longevity-focused over comfort focused treatment near EOL did not affect class membership. Conclusions This study is among the first to use text data from a real-world situation to extract information regarding individual foundations of morality. It is the first to test empirically if individual moral expressions are associated with individual characteristics, attitudes and emotions.


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