Characterization of forced degradation products and in silico toxicity prediction of Sofosbuvir: A novel HCV NS5B polymerase inhibitor

In Silico Toxicity ◽

Polymerase Inhibitor ◽

Hcv Ns5b ◽

Study of degradation behavior of besifloxacin, characterization of its degradation products by LC–ESI–QTOF–MS and their in silico toxicity prediction

Biomedical Chromatography ◽

10.1002/bmc.4489 ◽

2019 ◽

Vol 33 (6) ◽

pp. e4489 ◽

Author(s):

Nishant Salunke ◽

Prashant S. Kharkar ◽

Nancy Pandita

Keyword(s):

In Silico ◽

Degradation Products ◽

Degradation Behavior ◽

Toxicity Prediction ◽

Characterization of forced degradation products of canagliflozine by liquid chromatography/quadrupole time-of-flight tandem mass spectrometry and in silico toxicity predictions

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.8032 ◽

2018 ◽

Vol 32 (3) ◽

pp. 212-220 ◽

Cited By ~ 4

Author(s):

Shandilya Mahamuni Baira ◽

Pradipbhai D. Kalariya ◽

Rakesh Nimbalkar ◽

Prabha Garg ◽

R. Srinivas ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

In Silico ◽

Degradation Products ◽

Time Of Flight ◽

Forced Degradation ◽

Tandem Mass ◽

Structure Characterization of Degradation Products of Drug Candidate HM30571 by UPLC‐QTOF‐MS and In Silico Toxicity Prediction

Bulletin of the Korean Chemical Society ◽

10.1002/bkcs.11913 ◽

2019 ◽

Vol 41 (1) ◽

pp. 92-95

Author(s):

Hyojeong Bang ◽

Wankyunn Whang ◽

Keukchan Bang ◽

Eunyoung Lee ◽

Eunyoung Kim ◽

...

Keyword(s):

In Silico ◽

Degradation Products ◽

Structure Characterization ◽

Drug Candidate ◽

Toxicity Prediction ◽

845 PRECLINICAL PHARMACOKINETIC AND ADME CHARACTERIZATION OF VCH-916, A NOVEL NON-NUCLEOSIDE HCV NS5B POLYMERASE INHIBITOR

Journal of Hepatology ◽

10.1016/s0168-8278(08)60847-8 ◽

2008 ◽

Vol 48 ◽

pp. S317 ◽

Author(s):

N. Chauret ◽

C. Chagnon-Labelle ◽

M. Diallo ◽

J. Laquerre ◽

S. Plante

Keyword(s):

Polymerase Inhibitor ◽

Hcv Ns5b ◽

939 PRECLINICAL PHARMACOKINETIC AND ADME CHARACTERIZATION OF VCH-222, A NOVEL NON-NUCLEOSIDE HCV NS5B POLYMERASE INHIBITOR

Journal of Hepatology ◽

10.1016/s0168-8278(09)60941-7 ◽

2009 ◽

Vol 50 ◽

pp. S341-S342 ◽

Cited By ~ 2

Author(s):

N. Chauret ◽

C. Chagnon-Labelle ◽

M. Diallo ◽

J. Laquerre ◽

J. Laterreur ◽

...

Keyword(s):

Polymerase Inhibitor ◽

Hcv Ns5b ◽

UPLC, HR-MS, and in-silico tools for simultaneous separation, characterization, and in-silico toxicity prediction of degradation products of atorvastatin and olmesartan

Acta Chromatographica ◽

10.1556/1326.2017.00333 ◽

2019 ◽

Vol 31 (1) ◽

pp. 33-44 ◽

Author(s):

U. Rakibe ◽

R. Tiwari ◽

V. Rane ◽

P. Wakte

Keyword(s):

In Silico ◽

Degradation Products ◽

Toxicity Prediction ◽

Simultaneous Separation ◽

In Silico Toxicity ◽

In Silico Tools

Degradation Pathway Proposal, Structure Elucidation, and In Silico Toxicity Prediction of Dapagliflozin Propane Diol Hydrolytic Degradation Products

Chromatographia ◽

10.1007/s10337-020-03938-4 ◽

2020 ◽

Vol 83 (10) ◽

pp. 1233-1245 ◽

Author(s):

Prashant S. Devrukhakar ◽

M. Shiva Shankar

Keyword(s):

In Silico ◽

Structure Elucidation ◽

Degradation Products ◽

Hydrolytic Degradation ◽

Degradation Pathway ◽

Toxicity Prediction ◽

The First Kilogram Synthesis of Beclabuvir, an HCV NS5B Polymerase Inhibitor

Organic Process Research & Development ◽

10.1021/acs.oprd.8b00214 ◽

2018 ◽

Vol 22 (10) ◽

pp. 1393-1408 ◽

Cited By ~ 9

Author(s):

Jeffrey Bien ◽

Akin Davulcu ◽

Albert J. DelMonte ◽

Kenneth J. Fraunhoffer ◽

Zhinong Gao ◽

...

Keyword(s):

Polymerase Inhibitor ◽

Hcv Ns5b ◽

P0688 : Preclinical characterisation of MIV-802, a novel uridine nucleotide HCV NS5B polymerase inhibitor, for treatment of hepatitis C virus infection

Journal of Hepatology ◽

10.1016/s0168-8278(15)30891-6 ◽

2015 ◽

Vol 62 ◽

pp. S580 ◽

Author(s):

A. Lindqvist ◽

H. Kylefjord ◽

H. Wähling ◽

S. Juric ◽

S. Torssell ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Virus Infection ◽

Hepatitis C Virus Infection ◽

Uridine Nucleotide ◽

Polymerase Inhibitor ◽

Hcv Ns5b ◽

Identification of Degradation Products and Process Impurities from Terbutaline Sulfate by UHPLC-Q-TOF-MS/MS and In Silico Toxicity Prediction

Chromatographia ◽

10.1007/s10337-017-3259-5 ◽

2017 ◽

Vol 80 (5) ◽

pp. 793-804 ◽

Cited By ~ 4

Author(s):

Na Zhou ◽

Qi Qian ◽

Pengcheng Qi ◽

Jie Zhao ◽

Chunying Wang ◽

...

Keyword(s):

In Silico ◽

Degradation Products ◽

Toxicity Prediction ◽

Terbutaline Sulfate ◽

In Silico Toxicity ◽

Tof Ms