scholarly journals Association between Hospital Volume and Within-Hospital Intensive Care Unit Transfer for Sickle Cell Disease in Children's Hospitals

2015 ◽  
Vol 167 (6) ◽  
pp. 1306-1313 ◽  
Author(s):  
Jean L. Raphael ◽  
Troy Richardson ◽  
Matt Hall ◽  
Suzette O. Oyeku ◽  
David G. Bundy ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Hospital Volume ◽  
Cell Disease ◽  
Children's Hospitals ◽  
Hospital Intensive Care Unit ◽  
Children’S Hospitals ◽  
Intensive Care Unit Transfer

scholarly journals Patients with sickle cell disease and suspected COVID‐19 in a paediatric intensive care unit

2020 ◽  
Vol 190 (1) ◽  
Author(s):  
Claire Heilbronner ◽  
Laureline Berteloot ◽  
Pierre Tremolieres ◽  
Laurent Dupic ◽  
Laure Saint Blanquat ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Paediatric Intensive Care Unit ◽  
Paediatric Intensive Care ◽  
Cell Disease

scholarly journals Incidence of sickle cell disease patients with pulmonary embolism admitted to intensive care unit in Bahrain

2020 ◽  
Vol 41 (8) ◽  
pp. 802-807
Author(s):  
Fatema Mandeel ◽  
Hasan Saeed ◽  
Ahmed Alsadah ◽  
Sara Ahmed ◽  
Redha Al hammam
Keyword(s):  
Intensive Care Unit ◽  
Pulmonary Embolism ◽  
Intensive Care ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Cell Disease

Predictors of mortality in adults with Sickle cell disease admitted to intensive care unit in Bahrain

2017 ◽  
Vol 42 ◽  
pp. 238-242 ◽  
Author(s):  
Sana Abdulaaziz Al Khawaja ◽  
Zainab Mahdi Ateya ◽  
Ridha Abdulla Al Hammam
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Cell Disease ◽  
Predictors Of Mortality

Hospitalization Trend for Children and Adolescents with Sickle Cell Disease in the USA: A Pediatric Health Information Database Analysis

Blood ◽  
2012 ◽  
Vol 120 (21) ◽  
pp. 479-479
Author(s):  
Ram Kalpatthi ◽  
Brian R. Lee ◽  
Jignesh Dalal
Keyword(s):  
Sickle Cell Disease ◽  
Health Information ◽  
Sickle Cell ◽  
Clinical Care ◽  
Cell Disease ◽  
Children's Hospitals ◽  
Discharge Data ◽  
Pediatric Health ◽  
Children’S Hospitals ◽  
The Usa

Abstract Abstract 479 Introduction: Over the past several decades, survival of young children with sickle cell disease (SCD) has improved dramatically with innovations in basic science and clinical care Historically, interventions such as newborn screening, prophylactic penicillin, and immunization against invasive bacteria played a significant role in decreasing childhood mortality Other advances in preventive care such as hydroxyurea therapy and comprehensive care have been increasingly postulated as the next line of innovations to improve outcomes for children with SCD, particularly with respect to VOC. There is scanty literature about the pattern of hospitalization for children with SCD in US. As hospitalization consumes lots of economic resources, we studied the trend of hospitalization of children with sickle cell disease over the last decade. Methods: We used the Pediatric Health Information System (PHIS), a database of clinical and financial data from free-standing children's hospitals in the US. Only patients under the age of 21 who were hospitalized at one of the 35 PHIS hospitals that provided discharge data from 2000–2011 were included in the analysis. We examined patient demographics, timing of hospitalizations, complications, and prescription medication for these patients. The PHIS database provides an encrypted patient medical record number, thus we were able to follow patients over time. This allowed for a better visualization of the patient's hospitalizations, complications, and medications over 11 years. Results: From 2000 to 2011, there were 1635 unique pediatric patients with SCD accounting for 9222 hospitalizations in 35 children's hospitals in the USA. Overall, the number of new patients with SCD getting hospitalized has decreased consistently every year during the study period (Figure 1A). Specifically, there was a dramatic decrease in the number of new patients getting hospitalized in the southern USA compared to other regions. There was a sharp decline in the overall number of hospitalizations from the year 2003 to 2004 (1200 vs. 500 hospitalizations respectively). However, the hospitalization rate after 2004 remained similar till the year 2011. There was no difference between males and females in the hospitalizations rate. SCD patients aged 13–21 years accounted for higher number of hospitalizations where as patients aged 6–12 years accounted for the lower number of hospitalizations (Figure 1B). Patients with Hb-SS phenotype accounted for majority of the hospitalizations (Figure 1C). Vasoocclusive crises (VOC) remained the most common reason for hospitalization. There was only one hospitalization for pneumococcal sepsis (Table 1). There was only 250 patients (15%) were found to have receiving hydroxyurea. Conclusions: Our data show a decreasing trend of hospitalizations for new SCD patients in the USA suggesting an overall improvement of comprehensive health care for these patients. This is consistent with the report by Day et al from the United Kingdom. Despite MSH and Baby HUG study trials demonstrating the efficacy of hydroxyurea, it was significantly underutilized, as VOC remains the major indication of hospitalization. Studies addressing the barriers of hydroxyurea use, clinical trials of Vitamin D or glutamine supplementation are needed to prevent or decrease this major health burden (VOC) in this population. Disclosures: No relevant conflicts of interest to declare.

scholarly journals Trends in Sickle Cell Disease-related Priapism in U.S. Children's Hospitals

Urology ◽  
2016 ◽  
Vol 89 ◽  
pp. 118-122 ◽  
Author(s):  
Hsin-Hsiao Scott Wang ◽  
Katherine W. Herbst ◽  
Jennifer A. Rothman ◽  
Nirmish R. Shah ◽  
John S. Wiener ◽  
...  
Keyword(s):  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Cell Disease ◽  
Children's Hospitals ◽  
Children’S Hospitals

scholarly journals Characteristics and outcomes of patients with sickle cell disease admitted to pediatric intensive care: A retrospective review

2020 ◽  
Vol 11 (2) ◽  
pp. 68
Author(s):  
Ehab Hanafy ◽  
Mustafa Altoonisi ◽  
Al Jawharah Alghuraydh ◽  
Areej Alatawi ◽  
Badriah Alsabah ◽  
...  
Keyword(s):  
Intensive Care ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Retrospective Review ◽  
Pediatric Intensive Care ◽  
Cell Disease
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