scholarly journals Full-thickness rectal biopsy in children suspicious for Hirschsprung's disease is safe and yields a low number of insufficient biopsies

2018 ◽  
Vol 53 (10) ◽  
pp. 1942-1944 ◽  
Author(s):  
Niels Bjørn ◽  
Lars Rasmussen ◽  
Niels Qvist ◽  
Sönke Detlefsen ◽  
Mark Bremholm Ellebæk
Keyword(s):  
Hirschsprung's Disease ◽  
Hirschsprung’S Disease ◽  
Rectal Biopsy ◽  
Full Thickness

Experience with full-thickness rectal biopsy in the evaluation of patients with suspected Hirschsprung’s disease

2014 ◽  
Vol 10 (2) ◽  
pp. 42-45
Author(s):  
Kayode T. Bamigbola ◽  
Abdulrasheed A. Nasir ◽  
Lukman O. Abdur-Rahman ◽  
Adewale O. Oyinloye ◽  
Nurudeen T. Abdulraheem ◽  
...  
Keyword(s):  
Hirschsprung's Disease ◽  
Hirschsprung’S Disease ◽  
Rectal Biopsy ◽  
Full Thickness

scholarly journals Duhamel Procedure untuk Hirschsprung’s Disease Anak di RS Syaiful Anwar Malang

2021 ◽  
Vol 2 (2) ◽  
pp. 91-95
Author(s):  
Herry Wibowo
Keyword(s):  
Barium Enema ◽  
Anterior Resection ◽  
Low Anterior Resection ◽  
Hirschsprung's Disease ◽  
Hirschsprung’S Disease ◽  
Rectal Biopsy ◽  
Full Thickness ◽  
Duhamel Procedure ◽  
Pull Through ◽  
Age Range

Abstract— The diagnosis of Hirschprung's disease is made with barium enema and rectal biopsy in full thickness. The Duhamel procedure was performed in 8 cases in 2008 for cases of Hirschsprung's disease. Age range of patients 7 months to 11 years. The average body weight when operated on is 7-21 kg. Morbidity and mortality after surgery were not launched. Anorectal myectomy with low anterior resection, the Duhamel-Martin procedure, and the Soave pull-through endorectal procedure are the most acceptable methods for surgical management. Hirschsprung's disease was treated in Syaiful Anwar Hospital Malang in 2008 with the following data: 1 person in January (1 year), 1 person in February (6 years), 1 person in March (7 years), 3 people in April ( 7 months, 4 years and 2 years), 2 people in August 2008 (7 months and 11 years). Enlarged abdomen with bloating, repeated constipation and sometimes aborted. Withdrawal procedures that work with endorectal withdrawal procedures, all show long results Keywords: duhamel technique, hirschsprung's disease, constipation, infant   Abstrak— Diagnosis penyakit  Hirschprung  dibuat dengan barium enema dan full-thickness rectal biopsy. Duhamel procedure telah dilakukan pada 8 kasus pada tahun 2008 untuk kasus Hirschsprung's disease. Rentang usia penderita 7 bulan hingga 11 tahun. Berat badan rata – rata saat dioperasi 7 – 21 kg. Morbiditas dan mortalitas setelah operasi tidak dilaporkan. Anorectal myectomy dengan low anterior resection, Duhamel-Martin procedure, dan Soave endorectal pull-through procedure adalah metode yang paling dapat diterima untuk penatalaksanaan bedah. Didapatkan Kasus penyakit Hirschsprung's  yang berobat  di Rumah Sakit Syaiful Anwar Malang selama tahun 2008 dengan data sebagai berikut yaitu 1 orang  di Januari (1 tahun) , 1 orang di Februari (6 tahun), 1 orang Maret (7 bulan), 3 orang April (7 bulan, 4 tahun dan 2 tahun), 2 orang Agustus 2008 (7 bulan dan 11 tahun). Tiap penderita mengalami riwayat abdominal  distention dengan gejala perut kembung berulang, konstipasi dan kadang –kadang disertai mual. Delapan penderita yang menjalani operasi dengan prosedur endorectal pullthrough , semuanya menunjukkan hasil jangka panjang yang memuaskan. Kata kunci: tehnik duhamel, penyakit hirschsprung's , konstipasi, infant

Rectal Biopsy for Hirschsprung's Disease – Are We Performing too Many?

2010 ◽  
Vol 20 (02) ◽  
pp. 95-97 ◽  
Author(s):  
N. Rahman ◽  
J. Chouhan ◽  
S. Gould ◽  
Vt. Joseph ◽  
H. Grant ◽  
...  
Keyword(s):  
Hirschsprung's Disease ◽  
Hirschsprung’S Disease ◽  
Rectal Biopsy

Diagnosing Hirschsprung's disease: Increasing the odds of a positive rectal biopsy result

2003 ◽  
Vol 38 (3) ◽  
pp. 412-416 ◽  
Author(s):  
Nicola A. Lewis ◽  
Marc A. Levitt ◽  
Garret S. Zallen ◽  
Mona S. Zafar ◽  
Karen L. Iacono ◽  
...  
Keyword(s):  
Hirschsprung's Disease ◽  
Hirschsprung’S Disease ◽  
Rectal Biopsy ◽  
Biopsy Result

scholarly journals Hirschsprung’s Disease: Diagnosis and Management

2021 ◽  
Vol 10 (2) ◽  
pp. 104-113
Author(s):  
Md Benzamin ◽  
Md Rukunuzzaman ◽  
Md Wahiduzzaman Mazumder ◽  
ASM Bazlul Karim
Keyword(s):  
Hirschsprung's Disease ◽  
Hirschsprung’S Disease ◽  
Rectal Biopsy ◽  
Disease Diagnosis ◽  
Radiological Investigation ◽  
Functional Intestinal Obstruction ◽  
The Common ◽  
High Index Of Suspicion ◽  
Hirschprung's Disease ◽  
Related Mortality

Hirschsprung’s disease (HD) is a rare genetic congenital defect of intestine causing failure of migration of parasympathetic ganglionic cells in some definite part of intestine, resulting in functional intestinal obstruction. It commonly involves rectosigmoid region of colon but other parts of colon or total colon, even small intestine may be affected. Incidence is 1/5000 live births. It is one of the common pediatric surgical problems and 2nd most organic cause of constipation. Symptoms may be evident from 1st day of life. About 90% infants with Hirschprung’s disease fail to pass meconium in 1st 24 hours of life. About 80% HD cases are diagnosed in early few months of life and present with abdominal distention, constipation, poor feeding, vomiting etc. HD enterocolitis is a devastating condition related to mortality. HD may be associated with some congenital anomalies and syndrome. High index of suspicion is the main key to diagnosis. Radiological investigation supports the diagnosis and rectal biopsy for histopathology is confirmatory. Although it is a surgical problem, physician can play a key role in early diagnosis and thus help to prevent HD enterocolitis-related mortality and restore near-normal life. J Enam Med Col 2020; 10(2): 104-113

scholarly journals Pullthrough Operation for Hirschsprung's Disease: Importance of a Circumferential (Donut) Biopsy at the Level of the Anastomosis

2019 ◽  
Vol 07 (01) ◽  
pp. e55-e57
Author(s):  
Susan Jehangir ◽  
Soundappan Venkatraman Sannappa Soundappan ◽  
Micheal Krivanek ◽  
Susan Arbuckle ◽  
Nicole Graf
Keyword(s):  
Transition Zone ◽  
Transverse Colon ◽  
Hirschsprung's Disease ◽  
Hirschsprung’S Disease ◽  
Ganglion Cells ◽  
Distal Colon ◽  
Dentate Line ◽  
Full Thickness ◽  
Mesenteric Border ◽  
Antimesenteric Border

AbstractHirschsprung's disease is characterized by the absence of ganglia in the distal colon, resulting in a functional obstruction. It is managed by excision of the aganglionic segment and anastomosis of the ganglionated bowel just above the dentate line. The level of aganglionosis is determined by performing multiple seromuscular biopsies and/or full thickness biopsy on the antimesenteric border of the bowel to determine the level of pullthrough. The transition zone is described as being irregular, and hence a doughnut biopsy is recommended so that the complete circumference can be assessed. Herein, we described a child in whom there was a selective absence of ganglion cells in 30% of the circumference of the bowel along the mesenteric border for most of the transverse colon. This case defies the known concept of neural migration in an intramural and transmesenteric fashion and emphasizes the importance of a doughnut biopsy of the pulled-down segment.

Sign in / Sign up

Export Citation Format

Share Document