KELUWIH: Jurnal Kesehatan dan Kedokteran
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Published By University Of Surabaya

2715-6419

2021 ◽  
Vol 3 (1) ◽  
pp. 57-63
Author(s):  
Laura Victoria Christina ◽  
Astrid Pratidina Susilo

Abstract—Interprofessional collaboration is a collaboration in health services between health professionals from diverse backgrounds. One of the most important aspects of collaborative practice in health services is the communication between health professionals. Lack of communication can cause a delay in treatment and medical errors. Ineffective communication can also represent a lack of coordination. SBAR method is an effective communication technique for health professionals. The SBAR method is useful to improve team communication in general, improve communication skills in certain situations, and also helpful during shift handover.  Keywords: interprofessional collaboration, communication, SBAR method Abstrak—Kolaborasi interprofesional merupakan suatu kerja sama dalam pelayanan kesehatan antara profesional kesehatan yang memiliki latar belakang pendidikan berbeda. Dalam pelayanan kesehatan, salah satu hal terpenting dari praktik kolaborasi yaitu komunikasi antara tenaga kesehatan. Kurangnya komunikasi dapat menyebabkan terjadinya keterlambatan dalam melayani pasien dan kesalahan dalam menangani pasien. Komunikasi yang kurang efektif juga dapat menggambarkan koordinasi tenaga kesehatan yang kurang baik. Teknik komunikasi efektif yaitu SBAR ditetapkan sebagai standar komunikasi antara tenaga kesehatan yang berfokus terhadap pasien. Metode SBAR bermanfaat untuk meningkatkan komunikasi tim secara umum, meningkatkan keterampilan komunikasi saat situasi tertentu, dan juga berguna pada saat operan dinas. Kata kunci: kolaborasi interprofesional, komunikasi, metode SBAR    


2021 ◽  
Vol 3 (1) ◽  
pp. 9-21
Author(s):  
Wirda Anggraini

Abstract—Pneumonia was an inflammation that occurs in the lungs accompanied by exudation and consolidation of microorganisms. In Indonesia, the prevalence of pneumonia continues to increase. Treatment of pneumonia uses antibiotic therapy. The use of antibiotics needs to be controlled by evaluating the quality of antibiotic use to prevent negative effects that can occur on patients, such as antibiotic resistance. The purpose of this study was to determine the quality of antibiotic use in pneumonia patients. This study did with observational method with cross-sectional design. The study was conducted in August-September 2019. Qualitative evaluations did with Gyssen method. The results of 35 medical record samples that fulfill the criteria showed that 21.43% of cases category 0; 16.67% of cases category I; 0% of cases category II C; 33.34% of cases in category II B; 4.76% of cases category II A; 0% of cases category III B; 0% of cases category III A; 0% of cases category IV D; 19.05% of cases category IV C; 4.76% of cases category IV B; 61.90% of cases category IV A; 0% of cases category V; 0% of cases category VI. Thus, rational cases (category I) were 21,43% and irrational cases (categories I-IV) were 78,57%.


2021 ◽  
Vol 3 (1) ◽  
pp. 48-56
Author(s):  
Abednego Kristande Gwiharto ◽  
Cecep Suhandi ◽  
Cheryl Alodya ◽  
Rano K. Sinurya

Influenza is caused by a rapidly mutating viruse that consists of 2 types, namely type A with the H1N1 and H3N2 genotypes and type B. Influenza caused global mortality with 250,000-500,000 death in 2009. The effectiveness of vaccines also changes regarding the mutation of influenza viruses, however, in the development and utilization of influenza vaccines should be supported by the economic status of a country. Up to now, there are many countries that have not prioritized the utilization of influenza vaccines. The target of influenza vaccination are children and adults (> 60 years old). The purpose of this review was to determine the effectiveness of influenza vaccines from various countries and categorized based on their income. This review used Medline, Elsevier, and BMC Public Health as the database with the keywords "Effectiveness" and "Influenza vaccine". Then, the articles are selected based on inclusion and exclusion criteria. Based on the initial search there are 784 articles that match the keywords, and only 13 articles met the criteria. These articles are classified based on the center of the study in order to classify based on their national income; 5 studies in high income countries, 5 studies in upper-middle income countries, 3 studies in lower-middle income countries, and 1 study in low income countries. The results showed that the administration of influenza vaccine in high income and upper-middle income countries is quite effective for type A H1N1 genotypes, where as H3N2 is less effective. In the lower-middle income countries, the utilization of vaccines with type A H3N2 genotypes was effective, however, in the low-income countries, the effectiveness of vaccines has not been justified due to the limited study of type of influenza and the administration of influenza vaccines in those countries.  


2021 ◽  
Vol 3 (1) ◽  
pp. 1-8
Author(s):  
Febri Endra Budi Setyawan ◽  
Amalia Wahyu Natasari ◽  
Nesrin Zaharah ◽  
Divi Aditya Romadhona Putra ◽  
Wafiyah Hasanah ◽  
...  

Abstract—Occupational disease are important topic since they often occur in a long period of time. The purpose of this article is to find out how to prevent occupational diseases in the battery industry. This research is a systematic review of articles obtained through manual search engines from Google Scholars, Proquest, PubMed, Research Gate and has been published nationally and internationally in 2015-2020. The results of a systematic review were obtained from 30 scientific articles that were published nationally and internationally in 2015-2020 related to the battery industry process and related to occupational diseases. The factors contributing are varies from enviromental, biological, ergonomic, and the workers itself. There are several preventive management that can be done according to the analysis of the possible diseases that can be occured. Workers in the battery industry can experience occupational diseases, including: allergic contact dermatitis, bacterial conjunctivitis, noise-induced hearing loss, Low Back Pain and Carpal tunnel syndrome. Some prevention efforts that can be done include: using personal protective equipment, detecting workers who have a history of DKA, maintaining hygiene and cleanliness of the work environment, using furniture that is in accordance with ergonomic standards and not lifting heavy loads, reducing repetitive pressing movements and doing regular exercise. Keywords: preventive, allergic contact dermatitis, conjungtivitis, nihl, lbp, cts, battery industry   Abstrak—Penyakit akibat kerja menjadi perhatian penting karena muncul dalam jangka waktu panjang sehingga harus dilakukan upaya pencegahan penyakit. Penelitian ini merupakan review sistematik artikel yang diperoleh melalui melalui mesin pencari manual dari Google Scholars, Proquest, PubMed, Research Gate dan telah terpublikasi nasional maupun internasional pada tahun 2015-2020. Hasil review sistematik diperoleh dari 30 artikel ilmiah yang telah terpublikasi nasional maupun internasional pada tahun 2015-2020 yang terkait dengan proses industry baterai dan terkait dengan penyakit akibat kerja. Faktor penyebabnya juga berbagai macam karena faktor lingkungan, biologi, ergonomi, ataupun dari faktor pekerja. terdapat beberapa upaya preventif yang dapat disesuaikan dengan kemungkinan penyakit akibat kerja yang mungkin akan timbul. Pekerja di industri baterai dapat mengalami penyakit akibat kerja, antara lain: dermatitis kontak alergi, konjungtivitis bakteri, gangguan pendengaran akibat kebisingan, Low Back Pain dan Carpal tunnel syndrome. Beberapa upaya pencegahan yang dapat dilakukan antara lain: menggunakan alat pelindung diri, mendeteksi pekerja yang memiliki riwayat DKA, menjaga kebersihan dan kebersihan lingkungan kerja, menggunakan furnitur yang sesuai dengan standar ergonomis dan tidak mengangkat beban berat, mengurangi penekanan berulang. gerakan dan melakukan olahraga teratur. Kata Kunci: preventif, dermatitis kontak alergi (dka), konjungtivitis, nihl, lbp, cts, industri baterai


2021 ◽  
Vol 3 (1) ◽  
pp. 22-34
Author(s):  
Puri Safitri Hanum ◽  
Qory’ Hanifa

The study's objective was to describe the effect of using high doses of N-acetylcysteine on severe COVID-19 patients. It was evaluated from the length of stay and by monitoring the drug use data, laboratory data, and clinical data at Bhayangkara H.S Samsoeri Mertojoso Hospital Surabaya. The data was collected retrospectively from patients' Health Medical Records who got high dose N-acetylcysteine in October 2020 – February 2021, with standard therapy: antivirus (Remdesivir), antibiotics, vitamins, symptomatic and comorbid therapy, anticoagulant, and corticosteroids (Dexamethasone) as inclusion criteria, then described descriptively. The observation result confirmed that the use of a high dose of N-acetylcysteine (NAC) [1 x 1200 – 5000 mg] po/iv had effective results as seen from the patients' length of stay, which was 12 days for patients without comorbid and 14 days for patients with comorbid like diabetes and/or hypertension. The use of high dose NAC showed improvement in the patients' clinical condition that is evaluated from improved oxygen saturation by 37%. In addition, the laboratory results are shown an improvement in thorax X-ray by 69% and inflammatory markers like CRP and d-dimer by 100%. Further research that uses a prospective method is needed to get a better result on the use of high-dose NAC in patients with severe COVID-19.


2021 ◽  
Vol 3 (1) ◽  
pp. 35-47
Author(s):  
Denis Cristian Sudarno ◽  
Farida Suhud ◽  
Siswandono

Abstract—In this study, a new anticancer drug design for non-Hodgkin’s lymphoma was carried out, with a molecular docking approach from the compound 1-benzyl-3-benzoylurea parent and its analog as an anticancer compound. The purpose of the study was to obtain the best quantitative structure-activity relationship (QSAR). The in-silico activity test was carried out on the new 1-benzyl-3-benzoilurea and its analog compound against the Bruton Tyrosine Kinase receptor (BTK) PDB code (5FBN) by using the Molegro Virtual Docker 5.5 program and producing a RS (Rerank Score) value for the test compound and Acalabrutinib was used as a comparison. This study also conducted bioavailability by predicting the value of F (intestinal human absorption) in the pkCSM program and toxicity studies by predicting LD50 values using the Protox II program. Correlation and regression were performed using the RS, F, and LD50 values that we obtained on the physicochemical properties of the test compound using the IBM SPSS version 24 program. The best equation is obtained as follows: (1) F = 0.851 Es Taft - 6.116 σ - 1.969 π² + 3.620 π + 90.809;  (2) RS = 4.376 Es Taft - 88.802; (3) LD50 = 672.518 CMR - 669.385 ClogP - 813.806. From the results of the best equation is obtained that the activity is influenced by the parameters of steric physicochemical properties (Es Taft). Keywords: 1-benzyl-3-benzoylurea, code pdb:5fbn, in-silico, non-hodgkin lymphoma Abstrak—Pada penelitian ini dilakukan rancangan obat baru antikanker Limfoma non-Hodgkin, dengan pendekatan penambatan molekul dari senyawa induk 1-benzil-3-benzoilurea dan analognya sebagai senyawa antikanker.Tujuan penelitian ini untuk mendapatkan persamaan hubungan struktur aktivitas (HKSA) terbaik. Uji aktivitas in-silico dilakukan terhadap senyawa baru 1-benzil-3-benzoilurea dan analognya terhadap reseptor Bruton Tyrosine Kinase (BTK) kode PDB 5FBN dengan menggunakkan program Molegro Virtual Docker 5.5 dan menghasilkan nilai RS (Rerank Score) untuk senyawa uji dan Acalabrutinib digunakan sebagai pembanding. Penelitian ini juga dilakukan studi bioavaibilitas dengan memprediksi nilai F (intestinal human absorbtion) pada program pkCSM dan studi toksisitas dengan memprediksi nilai LD50 menggunakan program Protox II. Korelasi dan regresi dilakukan menggunakan nilai RS, F dan LD50 yang telah diperoleh terhadap parameter sifat fisikokimia senyawa uji menggunakan program IBM SPSS versi 24. Persamaan terbaik yang diperoleh sebagai berikut: (1) F = - 1.969 π² + 0.851 Es Taft - 6.116 σ + 3.620 π + 90.809 (2) RS = 4.376 Es Taft - 88.802 (3) LD50 = 672.518 CMR - 669.385 ClogP - 813.806. Dari hasil persamaan terbaik tersebut diperoleh bahwa aktivitas dipengaruhi oleh parameter sifat fisikokimia sterik (Es Taft). Kata kunci: 1-benzil-3-benzoilurea, in-silico, kode pdb: 5fbn, limfoma non-hodgkin


2021 ◽  
Vol 3 (1) ◽  
pp. 64-70
Author(s):  
Elita Halimsetiono

Salah satu dampak dari kesuksesan pembangunan nasional adalah Usia Harapan Hidup (UHH) yang makin meningkat yang berakibat pada jumlah lansia yang makin meningkat pula. Demi tercapainya peningkatan status kesehatan dan kualitas hidup lansia, maka seyogyanyalah pemerintah berkewajiban menyediakan sarana pelayanan kesehatan serta melakukan fasilitasi pada kelompok lansia agar dapat berkembang dengan baik, sehingga dapat tercipta lansia yang mandiri dan produktif. Sehubungan hal tersebut, maka pemerintah mengembangkan puskesmas lansia agar pelayanan kesehatan yang sifatnya holistik dan memadai, serta menekankan pada unsur proaktif, santun, kerjasama lintas sektor, kemudahan proses dan kesesuaian standar pelayanan, dapat diperoleh para lansia. Pelayanan promotif maupun preventif dapat dilakukan melalui keterlibatan dan partisipasi aktif masyarakat berupa posyandu lansia yang berasal dari puskesmas atau timbul dari aspirasi masyarakat itu sendiri. Dengan adanya pelayanan kesehatan yang memadai bagi para lansia, diharapkan peningkatan status kesehatan dan kualitas hidup lansia dapat tercapai, sehingga lansia memiliki hari tua yang berdaya guna dan juga bahagia sesuai dengan keberadaannya, dalam kehidupannya bersama dengan keluarga dan masyarakat.


2021 ◽  
Vol 2 (2) ◽  
pp. 91-95
Author(s):  
Herry Wibowo

Abstract— The diagnosis of Hirschprung's disease is made with barium enema and rectal biopsy in full thickness. The Duhamel procedure was performed in 8 cases in 2008 for cases of Hirschsprung's disease. Age range of patients 7 months to 11 years. The average body weight when operated on is 7-21 kg. Morbidity and mortality after surgery were not launched. Anorectal myectomy with low anterior resection, the Duhamel-Martin procedure, and the Soave pull-through endorectal procedure are the most acceptable methods for surgical management. Hirschsprung's disease was treated in Syaiful Anwar Hospital Malang in 2008 with the following data: 1 person in January (1 year), 1 person in February (6 years), 1 person in March (7 years), 3 people in April ( 7 months, 4 years and 2 years), 2 people in August 2008 (7 months and 11 years). Enlarged abdomen with bloating, repeated constipation and sometimes aborted. Withdrawal procedures that work with endorectal withdrawal procedures, all show long results Keywords: duhamel technique, hirschsprung's disease, constipation, infant   Abstrak— Diagnosis penyakit  Hirschprung  dibuat dengan barium enema dan full-thickness rectal biopsy. Duhamel procedure telah dilakukan pada 8 kasus pada tahun 2008 untuk kasus Hirschsprung's disease. Rentang usia penderita 7 bulan hingga 11 tahun. Berat badan rata – rata saat dioperasi 7 – 21 kg. Morbiditas dan mortalitas setelah operasi tidak dilaporkan. Anorectal myectomy dengan low anterior resection, Duhamel-Martin procedure, dan Soave endorectal pull-through procedure adalah metode yang paling dapat diterima untuk penatalaksanaan bedah. Didapatkan Kasus penyakit Hirschsprung's  yang berobat  di Rumah Sakit Syaiful Anwar Malang selama tahun 2008 dengan data sebagai berikut yaitu 1 orang  di Januari (1 tahun) , 1 orang di Februari (6 tahun), 1 orang Maret (7 bulan), 3 orang April (7 bulan, 4 tahun dan 2 tahun), 2 orang Agustus 2008 (7 bulan dan 11 tahun). Tiap penderita mengalami riwayat abdominal  distention dengan gejala perut kembung berulang, konstipasi dan kadang –kadang disertai mual. Delapan penderita yang menjalani operasi dengan prosedur endorectal pullthrough , semuanya menunjukkan hasil jangka panjang yang memuaskan. Kata kunci: tehnik duhamel, penyakit hirschsprung's , konstipasi, infant


2021 ◽  
Vol 2 (2) ◽  
pp. 110-114
Author(s):  
Devitya Angielevi Sukarno

Abstract--Insulin resistance underlies the pathogenesis of chronic disease, such as diabetes mellitus which has high morbidity and mortality rate. Insulin resistance is a pathological condition when cells fail to respond normally to the insulin hormone, because of insulin signaling pathway disruption. Bound between insulin and insulin’s receptor cannot phosphorylate tyrosine and fail to activate insulin receptor substrate-1 (IRS-1). This failure decrease Glucose transporter-4 (GLUT-4) expression on the skeletal muscle’s cell membrane, that leads to decrease glucose influx and increase blood glucose level. A routine physical training which does according to adequate training dose, will activate adenosin 5’monophosphate-activated protein kinase (AMPK) and lead to the translocation of GLUT-4 vesicles without insulin and insulin’s receptor bonding.GLUT-4 expression on the skeletal muscle’s cell membrane which is stimulated by muscle contraction will increase glucose influx and decrease blood glucose level. Keywords: insulin resistance; physical training; insulin signaling pathway   Abstrak--Resistensi insulin merupakan penyebab yang mendasari terjadinya penyakit kronis seperti diabetes melitus yang memiliki angka morbiditas dan mortalitas tinggi.Resistensi insulin merupakan keadaan patologis dimana terjadi kegagalan respon seluler terhadap hormon insulin akibat gangguan pada jalur sinyal insulin.Ikatan insulin pada reseptornya tidak dapat menyebabkan fosforilasi tirosin sehingga tidak dapat mengaktivasi insulin receptor substrate-1 (IRS-1). Kegagalan aktivasi tersebut akan menyebabkan penurunan ekspresi Glucose transporter-4 (GLUT-4) pada membran sel otot rangka sehingga ambilan glukosa oleh sel menurun dan glukosa darah meningkat. Latihan fisik yang dilakukan secara rutin, teratur dan sesuai dengan dosis latihan yang tepat dapat mengaktivasi adenosin 5’monophosphate-activated protein kinase (AMPK), sehingga menyebabkan translokasi vesikel berisi GLUT-4, tanpa melalui ikatan insulin dengan reseptornya. Ekspresi GLUT-4 pada membran sel yang dirangsang oleh kontraksi otot akan meningkatkan ambilan glukosa dan menurunkan glukosa darah. Kata kunci: resistensi insulin; latihan fisik; jalur sinyal insulin


2021 ◽  
Vol 2 (2) ◽  
pp. 82-90
Author(s):  
Muhammad Sultan

The potential hazards and risks in the household are many hazards from physical, chemical, biological and psychological factors. This study aims to explain the hazards of work in households. This study used a descriptive qualitative design with 7 family heads selected as informants. Information collection was carried out in November 2020 in Teluk Lerong Ulu Village, Samarinda City. Interviews and indepth interviews using qualitative interviews and data analysis. The results of the research show that the dangers and risks of work accidents that can cause hospital occupants and eye health problems due to poor lighting, burns, scratches or injuries due to sharp objects, being pinched, crushed and crushed by falling objects. Resident health complaints such as allergic itching and skin diseases, respiratory problems, and complaints of Musculoskeletal Disorder. If not managed properly, these hazards and risks can lead to prolonged health complaints and serious accidents. Therefore, efforts to deal with hazards and risks appropriately are defeated by the daily activities of residents of the household.


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