Doxorubicin loaded polymeric gold nanoparticles targeted to human folate receptor upon laser photothermal therapy potentiates chemotherapy in breast cancer cell lines

2015 ◽  
Vol 149 ◽  
pp. 116-128 ◽  
Author(s):  
Hussaina Banu ◽  
Dipinder Kaur Sethi ◽  
Andre Edgar ◽  
Adhnaan Sheriff ◽  
Nuthan Rayees ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Gold Nanoparticles ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Photothermal Therapy ◽  
Folate Receptor ◽  
Cancer Cell Lines ◽  
Breast Cancer Cell Lines ◽  
Human Folate Receptor

Anti Wnt-1 Monoclonal Antibody’s Conjugated with Gold Nanoparticles, Induced Apoptosis on MCF-7 Breast Cancer Cell Lines

2019 ◽  
Vol 58 ◽  
pp. 1-9 ◽  
Author(s):  
Mehdi Tayybi Azar ◽  
Necdet Saglam ◽  
Mustafa Turk
Keyword(s):  
Breast Cancer ◽  
Gold Nanoparticles ◽  
Monoclonal Antibodies ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cancer Cell Lines ◽  
Breast Cancer Cell Lines ◽  
Special Effect ◽  
Mcf 7

Wnt-β Catenin pathway has an important role in many cancers. Wnt-1 protein from the Wnt protein family, which regulates this pathway, has a special effect on the development of breast cancer. Monoclonal antibodies attaching to metal nanoparticles have an important role in the diagnosis and treatment of cancers.In this study, the anti-Wnt-1monoclonal antibody was conjugated to the gold nanoparticles synthesized by theTurkevichmethod. Conjugation was achieved using the EDC-NHS method. The density of the monoclonal antibodies bonded to gold nanoparticles was measured by Roche Cobas Integra 400 Plus device. MCF-7 and MDA-MB-231 breast cancer cell lines were treated with conjugated nanoparticles for 48 h, followed by performing a double-staining method to detect apoptosis cells.The results showed that inhibition of Wnt-1 protein in extracellular matrix causes apoptosis and gold nanoparticles to have a positive effect on Anti-Wnt-1monoclonal antibodies, leading to an increase in the number of conjugating nanoparticles.

Gold nanoparticles-conjugated quercetin induces apoptosis via inhibition of EGFR/PI3K/Akt-mediated pathway in breast cancer cell lines (MCF-7 and MDA-MB-231)

2017 ◽  
Vol 35 (4) ◽  
pp. 217-231 ◽  
Author(s):  
Solaimuthu Balakrishnan ◽  
Sudip Mukherjee ◽  
Sourav Das ◽  
Firdous Ahmad Bhat ◽  
Paulraj Raja Singh ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Gold Nanoparticles ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cancer Cell Lines ◽  
Breast Cancer Cell Lines ◽  
Mcf 7

Enhancement of radiation cytotoxicity by gold nanoparticles in MCF-7 breast cancer cell lines

2015 ◽  
Author(s):  
Nur Shafawati binti Rosli ◽  
Azhar Abdul Rahman ◽  
Azlan Abdul Aziz ◽  
Shaharum Shamsuddin
Keyword(s):  
Breast Cancer ◽  
Gold Nanoparticles ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cancer Cell Lines ◽  
Breast Cancer Cell Lines ◽  
Mcf 7

Anti-proliferative effect of biogenic gold nanoparticles against breast cancer cell lines (MDA-MB-231 & MCF-7)

2016 ◽  
Vol 371 ◽  
pp. 415-424 ◽  
Author(s):  
Uma Suganya K.S. ◽  
Govindaraju K. ◽  
Ganesh Kumar V. ◽  
Prabhu D. ◽  
Arulvasu C. ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Gold Nanoparticles ◽  
Cell Lines ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cancer Cell Lines ◽  
Breast Cancer Cell Lines ◽  
Proliferative Effect ◽  
Mcf 7
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