Structure dependent selective efficacy of pyridine and pyrrole based Cu(II) Schiff base complexes towards in vitro cytotoxicity, apoptosis and DNA-bases binding in ground and excited state

2016 ◽  
Vol 162 ◽  
pp. 463-472 ◽  
Author(s):  
Banabithi Koley Seth ◽  
Arpita Saha ◽  
Srijan Haldar ◽  
Partha Pratim Chakraborty ◽  
Partha Saha ◽  
...  
Keyword(s):  
Schiff Base ◽  
Excited State ◽  
In Vitro Cytotoxicity ◽  
Schiff Base Complexes ◽  
Dna Bases

Targeting ctDNA binding and elaborated in-vitro assessments concerning novel Schiff base complexes: Synthesis, characterization, DFT and detailed in-silico confirmation

2021 ◽  
Vol 322 ◽  
pp. 114977
Author(s):  
Ahmed M. Abu-Dief ◽  
Nashwa M. El-Metwaly ◽  
Seraj Omar Alzahrani ◽  
Afrah M. Bawazeer ◽  
Saad Shaaban ◽  
...  
Keyword(s):  
Schiff Base ◽  
In Silico ◽  
Schiff Base Complexes

para metallation of 3-acetyl-chromen-2-one Schiff bases in tetranuclear palladacycles: focus on their biomolecular interaction and in vitro cytotoxicity

2019 ◽  
Vol 48 (33) ◽  
pp. 12496-12511 ◽  
Author(s):  
G. Kalaiarasi ◽  
S. Dharani ◽  
V. M. Lynch ◽  
R. Prabhakaran
Keyword(s):  
Schiff Base ◽  
Schiff Bases ◽  
In Vitro Cytotoxicity ◽  
Biomolecular Interaction ◽  
Schiff Base Ligands

Three tetranuclear (1–3) complexes and a mononuclear (4) palladium(ii) complex were synthesized from 3-acetyl-chromen-2-one Schiff base ligands [H2-3MAC-Rtsc] (where R = H; CH3; C2H5[H2-3MAC-etsc] or C6H5) and potassium tetrachloropalladate.

scholarly journals Synthesis, Spectroscopic, Molecular Structure, and Antibacterial Studies of Dibutyltin(IV) Schiff Base Complexes Derived from Phenylalanine, Isoleucine, and Glycine

2014 ◽  
Vol 2014 ◽  
pp. 1-12 ◽  
Author(s):  
Har Lal Singh ◽  
Jangbhadur Singh
Keyword(s):  
Amino Acids ◽  
Schiff Base ◽  
Schiff Bases ◽  
Molar Conductance ◽  
Schiff Base Complexes ◽  
Spectral Studies ◽  
E Coli ◽  
Elemental Analyses ◽  
In Vitro Antibacterial Activity

New series of organotin(IV) complexes and Schiff bases derived from amino acids have been designed and synthesized from condensation of1H-indole-2,3-dione, 5-chloro-1H-indole-2,3-dione, andα-amino acids (phenylalanine, isoleucine, and glycine). All compounds are characterized by elemental analyses, molar conductance measurements, and molecular weight determinations. Bonding of these complexes is discussed in terms of their UV-visible, infrared, and nuclear magnetic resonance (1H,13C, and119Sn NMR) spectral studies. The results suggest that Schiff bases behave as monobasic bidentate ligands and coordinate with dibutyltin(IV) in octahedral geometry according to the general formula [Bu2Sn(L)2]. Elemental analyses and NMR spectral data of the ligands with their dibutyltin(IV) complexes agree with their proposed distorted octahedral structures. Few representative compounds are tested for their in vitro antibacterial activity against Gram-positive (B. cereus,Staphylococcusspp.) and Gram-negative (E. coli,Klebsiellaspp.) bacteria. The results show that the dibutyltin complexes are more reactive with respect to their corresponding Schiff base ligands.

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