Prediction of Local Recurrence After Oncoplastic Breast Surgery: Analysis of a Large Cohort

2021 ◽  
Vol 268 ◽  
pp. 267-275
Author(s):  
Mohammadreza Tabary ◽  
Farnaz Araghi ◽  
Mehdi Nouraie ◽  
Armin Aryannejad ◽  
Sanaz Zand ◽  
...  
2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Wolfram Malter ◽  
Verena Kirn ◽  
Lisa Richters ◽  
Claudius Fridrich ◽  
Birgid Markiefka ◽  
...  

Breast-conserving surgery followed by whole-breast irradiation is the standard local therapy for early breast cancer. The international discussion of reduced importance of wider tumor-free resection margins than “tumor not touching ink” leads to the development of five principles in targeted oncoplastic breast surgery. IORT improves local recurrence risk and diminishes toxicity since there is less irradiation of healthy tissue. Intraoperative radiotherapy (IORT) can be delivered in two settings: an IORT boost followed by a conventional regimen of external beam radiotherapy or a single IORT dose. The data from TARGIT-A and ELIOT reinforce the conviction that intraoperative radiotherapy during breast-conserving surgery is a reliable alternative to conventional postoperative fractionated irradiation, but only in a carefully selected population at low risk of local recurrence. We describe our experiences with IORT boost (50 kV energy X-rays; 20 Gy) in combination with targeted oncoplastic breast surgery in a routine clinical setting. Our experiences demonstrate the applicability and reliability of combining IORT boost with targeted oncoplastic breast surgery in breast-conserving therapy of early breast cancer.


2019 ◽  
Vol 26 (12) ◽  
pp. 2222-2230
Author(s):  
Saira Saleem ◽  
Farhan Javed ◽  
Ayesha Rehman ◽  
Nazim Hayat ◽  
Nadia Bano ◽  
...  

Objectives: Oncoplastic breast surgery (OBS) is a revolutionary approach for managing breast cancer. This manuscript aimed to assess the oncological and cosmetic outcomes of OBS in breast cancer. Study Design: Descriptive, prospective study. Setting: Department of Surgery, Madina Teaching Hospital, Faisalabad. Period: January 2018 to June 2019. Material & Methods: Females with invasive breast cancer having 5-6 cm tumour size, Locally advanced tumour after chemotherapy, single tumour and patients < 70 years were included; while patients with fixed tumours, high tumour to breast size ratio, multiple axillary lymph nodes, metastatic cancer & patient’s choice for mastectomy were excluded. Oncological outcome was assessed by; Margin involvement, time lag for chemotherapy, local recurrence and distant metastasis. Cosmetic outcome was detected by score given by patient and an independent surgeon. Results: Thirty two female patients underwent OBS. Mean age of patients was 46.56 yr (SD =10.23). Six patients (18.8%) had central tumors. 3 patients were post neoadjuvant chemotherapy. In 28 patients volume displacement (VD) surgery; while in 4 patients volume replacement (VR) using different flaps like LICAP flap were done. Oncological outcome showed positive margin in one case only, in all other cases clear margins were found. Chemotherapy start time varied from 3 to 8 weeks after surgery (Mean=31.3 days). Delayed time was associated with high BMI and diabetes (P<0.05). Local recurrence or distant metastasis was not noticed in any case. Majority of the patients and surgeon (90%) were satisfied with cosmetic outcome. Conclusion: Oncoplastic Breast surgery is a unique approach to conserve breast even in larger tumours without compromise on oncological principles and cosmesis.  


2021 ◽  
Vol 94 ◽  
pp. 102158
Author(s):  
Alexander Bartram ◽  
Fiona Gilbert ◽  
Alastair Thompson ◽  
G Bruce Mann ◽  
Amit Agrawal

2017 ◽  
Vol 24 (3) ◽  
pp. 432-434 ◽  
Author(s):  
Ruffo Freitas-Junior ◽  
Sara Socorro Faria ◽  
Régis Resende Paulinelli ◽  
Edésio Martins

2011 ◽  
Vol 127 (2) ◽  
pp. 1012-1013 ◽  
Author(s):  
Anita A. Liem ◽  
Azhar Iqbal

2021 ◽  
pp. 1-10
Author(s):  
Katrine Rye Hauerslev ◽  
Jens Overgaard ◽  
Tine Engberg Damsgaard ◽  
Helle Mikel Hvid ◽  
Eva Balling ◽  
...  

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