Characterization of Baseline Temperature Characteristics Using Thermography in The Clinical Setting

Two versions of Schmitt trigger, an emitter-coupled and an operational amplifier (opamp)-based, are implemented in 4H-SiC bipolar technology and tested up to 500 °C. The former benefits the simplicity, smaller footprint, and fewer number of devices, whereas the latter provides better promise for high temperature applications, thanks to its more stable temperature characteristics. In addition, the measurements in the range 25 °C - 500 °C, shows that the opamp-based version provides negative and positive slew rates of 4.8 V/µs and 8.3 V/µs, ~8 and ~3 times higher than that of the emitter-coupled version, which are 1.7 V/µs and 1 V/µs.

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Enterobacter cloacae producing an uncommon class A carbapenemase, IMI-1, from Singapore

Journal of Medical Microbiology ◽

10.1099/jmm.0.053363-0 ◽

2013 ◽

Vol 62 (7) ◽

pp. 1086-1088 ◽

Cited By ~ 18

Author(s):

Jeanette W. P. Teo ◽

My-Van La ◽

Prabha Krishnan ◽

Brenda Ang ◽

Roland Jureen ◽

...

Keyword(s):

Clinical Setting ◽

Enterobacter Cloacae ◽

Class A

In this study, we describe the characterization of an infrequently encountered class A carbapenemase, IMI-1, from a clinical Enterobacter cloacae isolate. The isolate had high levels of resistance to carbapenems but retained susceptibility to expanded-spectrum cephalosporins. The bla IMI-1 gene was chromosomally encoded. Detection of the IMI-1 producer highlights the diversity of carbapenemases in a local clinical setting.

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A Framework for Characterizing Terminological Systems

Methods of Information in Medicine ◽

10.1055/s-0038-1634079 ◽

2006 ◽

Vol 45 (03) ◽

pp. 253-266 ◽

Cited By ~ 11

Author(s):

N. F. de Keizer ◽

A. Abu-Hanna ◽

R. Cornet

Keyword(s):

Clinical Setting ◽

Snomed Ct ◽

Uniform Approach ◽

Feature Based ◽

Mutual Comparison ◽

Respective Type ◽

Content Coverage ◽

Independent Features

Summary Objectives: The notion of a terminological system (TS) is complex due to the broad range of systems, applications, and clinical domains. A uniform approach to describe the characteristics of TSs is lacking. This impedes furthering understanding, applicability, mutual comparison and development of TSs. For these reasons we propose a terminological systems characterization framework. Methods: Relevant issues pertaining to TSs and terminology servers have been extracted from literature describing requirements and functionality of TSs. From these issues, features have been distilled and further refined. A categorization has been developed to provide a convenient arrangement of these features. Results: The framework distinguishes between application-dependent and application-independent features of TSs. Definitions are provided for measures of content coverage, which was identified as the only application-dependent feature. Application-independent features are categorized along two axes: their respective type of TS and the particular element within that system, i.e. the formalism, the content, or the functionality. For each feature we provide an explicit question, the answer to which yields a feature value. The framework has been applied to SNOMED CT and the CLUE browser. Conclusions: We present and apply a framework to support a feature-based characterization of terminological systems. Standardized methods for content coverage studies reduce the effort of assessing the applicability of a TS for a specific clinical setting. A two-axial categorization provides a convenient arrangement of the large number of application-independent features. Application of the framework increases comparability of terminological systems. This framework may also help TS developers determine how their system can be improved.

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MDS PSP criteria in real-life clinical setting: Motor and cognitive characterization of subtypes

Movement Disorders ◽

10.1002/mds.27408 ◽

2018 ◽

Vol 33 (8) ◽

pp. 1361-1365 ◽

Cited By ~ 9

Author(s):

Marina Picillo ◽

Roberto Erro ◽

Sofia Cuoco ◽

Maria Francesca Tepedino ◽

Renzo Manara ◽

...

Keyword(s):

Clinical Setting ◽

Real Life

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Nanophotonics for Molecular Diagnostics and Therapy Applications

International Journal of Photoenergy ◽

10.1155/2012/619530 ◽

2012 ◽

Vol 2012 ◽

pp. 1-11 ◽

Cited By ~ 23

Author(s):

João Conde ◽

João Rosa ◽

João C. Lima ◽

Pedro V. Baptista

Keyword(s):

Molecular Diagnostics ◽

Clinical Setting ◽

Chemical Nature ◽

Molecular Complexes ◽

Specific Sequence ◽

Sequence Characterization ◽

Physical Chemical ◽

Therapy Strategies ◽

Diagnostics And Therapy

Light has always fascinated mankind and since the beginning of recorded history it has been both a subject of research and a tool for investigation of other phenomena. Today, with the advent of nanotechnology, the use of light has reached its own dimension where light-matter interactions take place at wavelength and subwavelength scales and where the physical/chemical nature of nanostructures controls the interactions. This is the field of nanophotonics which allows for the exploration and manipulation of light in and around nanostructures, single molecules, and molecular complexes. What is more is the use of nanophotonics in biomolecular interactions—nanobiophotonics—has prompt for a plethora of molecular diagnostics and therapeutics making use of the remarkable nanoscale properties. In this paper, we shall focus on the uses of nanobiophotonics for molecular diagnostics involving specific sequence characterization of nucleic acids and for gene delivery systems of relevance for therapy strategies. The use of nanobiophotonics for the combined diagnostics/therapeutics (theranostics) will also be addressed, with particular focus on those systems enabling the development of safer, more efficient, and specific platforms. Finally, the translation of nanophotonics for theranostics into the clinical setting will be discussed.

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