096 Recent Institutional Experience with Penile Duplex Doppler Ultrasound in Patients with Erectile Dysfunction

Introduction: This study aimed to explore the time-effect of color duplex Doppler ultrasound (CDDU) in the diagnosis of vascular erectile dysfunction (ED).Material and methods: Using a self-control study, we included patients who underwent penile CDDU and cavernosography in our hospital. We compared the arterial peak systolic velocity (PSV) of CDDU among different intervals for the diagnosis of arterial ED. We included 357 patients who were under consideration for vascular ED.Results: We found significant differences in all the pairwise comparison of PSV in the 1st (0–5 min), 2nd (6–10 min), 3rd (11–15 min), and 4th (16–20 min) 4 intervals after the injection of prostaglandin E1 (p<0.001), except the 11–15 min vs. the 16–20 min interval (p=0.387). Using cavernosography, 294 patients were diagnosed with venous ED. Compared with other intervals, the diagnosis of CDDU 11–15 min after the intracavernous injection of 20 ug prostaglandin E1 (PGE1) had the best consistency with cavernosography (Kappa=0.761; p<0.001). Compared with other intervals, CDDU at 11–15 min had the highest specificity (93.65%), the highest Youden index (0.85), positive likelihood ratio of 14.46, positive predictive value of 98.54%, negative predictive value of 71.08% and a coincidence rate of 92.16%.Conclusions: Our findings support the increased utilization of CDDU for the diagnosis of both arterial and venous ED. The diagnosis at 11–15 min after intracavernous injection of PGE1 is accurate and stable, which would help to simplify the process and shorten the time of CDDU.

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A Critical Analysis of Methodology Pitfalls in Duplex Doppler Ultrasound in the Evaluation of Patients With Erectile Dysfunction: Technical and Interpretation Deficiencies

Journal of Sexual Medicine ◽

10.1016/j.jsxm.2020.05.023 ◽

2020 ◽

Vol 17 (8) ◽

pp. 1416-1422

Author(s):

Bruno Nascimento ◽

Eduardo P. Miranda ◽

Jean-Etienne Terrier ◽

Felipe Carneiro ◽

John P. Mulhall

Keyword(s):

Erectile Dysfunction ◽

Doppler Ultrasound ◽

Critical Analysis ◽

Duplex Doppler Ultrasound ◽

Duplex Doppler

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Relationship between Response to PDE5 Inhibitors and Penil Duplex Doppler Ultrasound in Erectile Dysfunction

10.20944/preprints201801.0196.v1 ◽

2018 ◽

Author(s):

Ercan Ogreden ◽

Ural Oğuz ◽

Erhan Demirelli ◽

Alptekin Tosun ◽

Orhan Yalçın

Keyword(s):

Erectile Dysfunction ◽

Doppler Ultrasound ◽

Venous Insufficiency ◽

Response To Treatment ◽

Group Iii ◽

Duplex Doppler Ultrasound ◽

Group I ◽

Arterial Insufficiency ◽

Duplex Doppler ◽

Group Ii

Relationship between the results of penile duplex doppler ultrasound (PDDU) and response to vardenafil was investigated in patients diagnosed with erectile dysfunction (ED). Data of 148 patients with ED were analysed retrospectively. Patients who did not respond to therapy were classified as Group I (n = 32), those responded partially were classified as Group II (n = 40) and complete responders were classified as Group III (n = 76). Age, comorbid diseases, vascular and penile pathology were compared among the three groups. While diabetes mellitus (DM) and dyslipedimia positivity adversely affect the response to treatment, the presence of hypertension (HT), peyronie's disease and priapism increase the therapeutic response to the treatment (p < 0.05). Arterial insufficiency was present in 20(30.3%), 25(37,9%) and 21(31.8%) of the patients in Group I, Group II and Group III, respectively (p = 0.001). Venous insufficiency was observed in 3(14.3%) patients in Group I and in 8(85.7%) patients in Group III (p = 0.001). Arterial/venous insufficiency was seen in 9(30%), 14(46.7%) and 7(23.3%) of the patients in Group I, Group II and Group III, respectively (p = 0.001). Response rate to treatment was highest in normal patients according to PDDU, followed by patients with venous insuffiency. Besides, it was found that DM decreased the response to treatment, whereas response was increased in cases with HT, priapism and Peyronie’s disease.

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