scholarly journals Time-effect of penile color duplex Doppler ultrasound for diagnosing vascular erectile dysfunction

2020 ◽  
Vol 1 (1) ◽  
pp. 37
Author(s):  
Jin Wang ◽  
Jing Wang ◽  
Qian Liu ◽  
Huijun Jia ◽  
Cuihong Zhang ◽  
...  

Introduction: This study aimed to explore the time-effect of color duplex Doppler ultrasound (CDDU) in the diagnosis of vascular erectile dysfunction (ED).Material and methods: Using a self-control study, we included patients who underwent penile CDDU and cavernosography in our hospital. We compared the arterial peak systolic velocity (PSV) of CDDU among different intervals for the diagnosis of arterial ED. We included 357 patients who were under consideration for vascular ED.Results: We found significant differences in all the pairwise comparison of PSV in the 1st (0–5 min), 2nd (6–10 min), 3rd (11–15 min), and 4th (16–20 min) 4 intervals after the injection of prostaglandin E1 (p<0.001), except the 11–15 min vs. the 16–20 min interval (p=0.387). Using cavernosography, 294 patients were diagnosed with venous ED. Compared with other intervals, the diagnosis of CDDU 11–15 min after the intracavernous injection of 20 ug prostaglandin E1 (PGE1) had the best consistency with cavernosography (Kappa=0.761; p<0.001). Compared with other intervals, CDDU at 11–15 min had the highest specificity (93.65%), the highest Youden index (0.85), positive likelihood ratio of 14.46, positive predictive value of 98.54%, negative predictive value of 71.08% and a coincidence rate of 92.16%.Conclusions: Our findings support the increased utilization of CDDU for the diagnosis of both arterial and venous ED. The diagnosis at 11–15 min after intracavernous injection of PGE1 is accurate and stable, which would help to simplify the process and shorten the time of CDDU.

2021 ◽  
Vol 18 (3) ◽  
pp. S51-S52
Author(s):  
J. Kim ◽  
J. Greenberg ◽  
M. Polchert ◽  
C. Natale ◽  
B. Dick ◽  
...  

2018 ◽  
Vol 6 (2) ◽  
pp. 28
Author(s):  
Ercan Ogreden ◽  
Ural Oğuz ◽  
Erhan Demirelli ◽  
Alptekin Tosun ◽  
Orhan Yalçın

2016 ◽  
Vol 88 (3) ◽  
pp. 183 ◽  
Author(s):  
Fabio Pezzoni ◽  
Fabrizio Ildefonso Scroppo

Objectives. In 2013 the International Society for Sexual Medicine(ISSM) published the guidelines regarding the standard operating procedure (SOP) for penile duplex Doppler ultrasound (PDDU). Although ISSM-SOP have given important strides in reducing interobserver variability in PDDU by procedural protocol and parameters these guidelines do not address the anatomic location along the penis at which hemodynamic measurements have to be done. In our opinion a “double sampling” may be interesting to detect the arteriogenic or venogenic nature of the erectile dysfunction (ED). In particular sampling measurements at the “crus” (at the level of the peno-scrotal junction) may be significative for detection of veno-occlusive dysfunction (VOD),whereas an evaluation at “mid penis” (1/2 distance between peno-scrotal junction and coronal sulcus), may be useful to diagnose an arterial insufficiency (AI). Material and Methods. We evalued 90 men, mean age 56.3, affected with ED of medium degree, responder to PDE5-I that urdergone to PDDU and also responder after pharmacologic intracavernosal injection (PII)of prostaglandin E1 20 mcg, with rigid erection and normal maintenance. We moreover evalued 90 men in youthful age (mean 35.2), in absence of vascular risk factors, no responder to PDE5-I that undergone to PDDU by PII at high dosage (bimix: prostaglandin E1 20 mcg, papaverine 20 mg). Results. In the first pool the sampling at “mid penis” resulted significative for arterial insuffciency (AI) in 81% (73), in presence of normal or borderline end diastolic velocity (EDV). Sampling at the “crus” resulted negative for VOD in 90% (81). In the second pool, 66.6% (60) resulted responder with rigid erection and normal maintenance in presence of normal hemodynamic parameters: peak systolic velocity (PSV) and end diastolic velocity (EDV) both at the “crus” and at “mid penis” sampling. 33.4% (30) responded with a semirigid erection and manifested a constant deficit of maintenance; at the “crus”and at “mid penis” the hemodynamic arterial parameters resulted normal. At the “crus” the EDV resulted significantly augmented (VOD index) in 96.6% (29); at “mid penis” augmented EDV was founded in 50% (15). Conclusions. These observational data would be able to confirm the utility of a routinary “double sampling” procedure, at the “crus” and at “md penis”, during PDDU in order to better distinguish between VOD or AI or in any case to be useful to stimulate a future more precise standardization in execution of PDDU examination.


Author(s):  
Ercan Ogreden ◽  
Ural Oğuz ◽  
Erhan Demirelli ◽  
Alptekin Tosun ◽  
Orhan Yalçın

Relationship between the results of penile duplex doppler ultrasound (PDDU) and response to vardenafil was investigated in patients diagnosed with erectile dysfunction (ED). Data of 148 patients with ED were analysed retrospectively. Patients who did not respond to therapy were classified as Group I (n = 32), those responded partially were classified as Group II (n = 40) and complete responders were classified as Group III (n = 76). Age, comorbid diseases, vascular and penile pathology were compared among the three groups. While diabetes mellitus (DM) and dyslipedimia positivity adversely affect the response to treatment, the presence of hypertension (HT), peyronie's disease and priapism increase the therapeutic response to the treatment (p &lt; 0.05). Arterial insufficiency was present in 20(30.3%), 25(37,9%) and 21(31.8%) of the patients in Group I, Group II and Group III, respectively (p = 0.001). Venous insufficiency was observed in 3(14.3%) patients in Group I and in 8(85.7%) patients in Group III (p = 0.001). Arterial/venous insufficiency was seen in 9(30%), 14(46.7%) and 7(23.3%) of the patients in Group I, Group II and Group III, respectively (p = 0.001). Response rate to treatment was highest in normal patients according to PDDU, followed by patients with venous insuffiency. Besides, it was found that DM decreased the response to treatment, whereas response was increased in cases with HT, priapism and Peyronie&rsquo;s disease.


1991 ◽  
Vol 1 (2) ◽  
pp. 108-112
Author(s):  
A. Elvin ◽  
T. Andersson ◽  
B. Eriksson ◽  
K. �berg

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