scholarly journals Relationship between Response to PDE5 Inhibitors and Penil Duplex Doppler Ultrasound in Erectile Dysfunction

2018 ◽  
Author(s):  
Ercan Ogreden ◽  
Ural Oğuz ◽  
Erhan Demirelli ◽  
Alptekin Tosun ◽  
Orhan Yalçın
Keyword(s):  
Erectile Dysfunction ◽  
Doppler Ultrasound ◽  
Venous Insufficiency ◽  
Response To Treatment ◽  
Group Iii ◽  
Duplex Doppler Ultrasound ◽  
Group I ◽  
Arterial Insufficiency ◽  
Duplex Doppler ◽  
Group Ii

Relationship between the results of penile duplex doppler ultrasound (PDDU) and response to vardenafil was investigated in patients diagnosed with erectile dysfunction (ED). Data of 148 patients with ED were analysed retrospectively. Patients who did not respond to therapy were classified as Group I (n = 32), those responded partially were classified as Group II (n = 40) and complete responders were classified as Group III (n = 76). Age, comorbid diseases, vascular and penile pathology were compared among the three groups. While diabetes mellitus (DM) and dyslipedimia positivity adversely affect the response to treatment, the presence of hypertension (HT), peyronie's disease and priapism increase the therapeutic response to the treatment (p < 0.05). Arterial insufficiency was present in 20(30.3%), 25(37,9%) and 21(31.8%) of the patients in Group I, Group II and Group III, respectively (p = 0.001). Venous insufficiency was observed in 3(14.3%) patients in Group I and in 8(85.7%) patients in Group III (p = 0.001). Arterial/venous insufficiency was seen in 9(30%), 14(46.7%) and 7(23.3%) of the patients in Group I, Group II and Group III, respectively (p = 0.001). Response rate to treatment was highest in normal patients according to PDDU, followed by patients with venous insuffiency. Besides, it was found that DM decreased the response to treatment, whereas response was increased in cases with HT, priapism and Peyronie’s disease.

096 Recent Institutional Experience with Penile Duplex Doppler Ultrasound in Patients with Erectile Dysfunction

2021 ◽  
Vol 18 (3) ◽  
pp. S51-S52
Author(s):  
J. Kim ◽  
J. Greenberg ◽  
M. Polchert ◽  
C. Natale ◽  
B. Dick ◽  
...  
Keyword(s):  
Erectile Dysfunction ◽  
Doppler Ultrasound ◽  
Duplex Doppler Ultrasound ◽  
Institutional Experience ◽  
Duplex Doppler

scholarly journals Relationship between Response to PDE5 Inhibitors and Penile Duplex Doppler Ultrasound in Erectile Dysfunction

2018 ◽  
Vol 6 (2) ◽  
pp. 28
Author(s):  
Ercan Ogreden ◽  
Ural Oğuz ◽  
Erhan Demirelli ◽  
Alptekin Tosun ◽  
Orhan Yalçın
Keyword(s):  
Erectile Dysfunction ◽  
Doppler Ultrasound ◽  
Pde5 Inhibitors ◽  
Duplex Doppler Ultrasound ◽  
Duplex Doppler

scholarly journals Reliability of Carotid Doppler performed in a dedicated Stroke Prevention Clinic

2005 ◽  
Vol 32 (3) ◽  
pp. 327-331 ◽  
Author(s):  
N. Dean ◽  
H. Lari ◽  
M. Saqqur ◽  
N. Amir ◽  
K. Khan ◽  
...  
Keyword(s):  
Doppler Ultrasound ◽  
Cerebral Angiography ◽  
Stroke Prevention ◽  
Screening Tool ◽  
Misclassification Rate ◽  
Group Iii ◽  
Group I ◽  
Group Ii ◽  
Ica Stenosis ◽  
Prevention Clinic

ABSTRACT:Introduction:Doppler ultrasound (DUS) is used as a screening tool to assess internal carotid artery (ICA) disease. Recent reports suggest that the DUS may be inaccurate in over 28% of patients. We sought to evaluate the accuracy of DUS, when performed in a dedicated stroke prevention clinic (SPC).Methods:We retrospectively reviewed the charts of patients who had a DUS performed in our SPC, followed by conventional cerebral angiography. Three groups of patients were defined. Group 1 had DUS measured ICA stenosis of >50%; Group II had a DUS measured ICA stenosis of <50%; Group III had complete ICA occlusion on DUS.Results:Sixty-seven patients (69 arteries) were included in the study. There were 45 patients in Group I and based on the findings of cerebral angiography, carotid endarterectomy was considered inappropriate in only one patient. - a misclassification rate of 2.2% (95%CI: 0 – 6.5%). Group II consisted of 19 patients and on cerebral angiography, none of these patients had a stenosis of >50% - a misclassification rate of 0%. Group III consisted of five patients in whom DUS showed complete ICA occlusion. The angiogram confirmed the occlusion in all five patients – a misclassification rate of 0%. Overall, misclassification rate was 1.45% (95% CI: 0 - 4.3%).Conclusions:Doppler ultrasound when performed in a stroke prevention clinic (SPC), has a high accuracy in measuring ICA stenosis of >50%. Doppler ultrasound is reliable in detecting complete ICA occlusion and finally DUS is a reliable screening tool to rule out clinically significant ICA stenosis.

scholarly journals Time-effect of penile color duplex Doppler ultrasound for diagnosing vascular erectile dysfunction

2020 ◽  
Vol 1 (1) ◽  
pp. 37
Author(s):  
Jin Wang ◽  
Jing Wang ◽  
Qian Liu ◽  
Huijun Jia ◽  
Cuihong Zhang ◽  
...  
Keyword(s):  
Erectile Dysfunction ◽  
Doppler Ultrasound ◽  
Predictive Value ◽  
Prostaglandin E1 ◽  
Positive Likelihood Ratio ◽  
Time Effect ◽  
Youden Index ◽  
Intracavernous Injection ◽  
Duplex Doppler Ultrasound ◽  
Duplex Doppler

Introduction: This study aimed to explore the time-effect of color duplex Doppler ultrasound (CDDU) in the diagnosis of vascular erectile dysfunction (ED).Material and methods: Using a self-control study, we included patients who underwent penile CDDU and cavernosography in our hospital. We compared the arterial peak systolic velocity (PSV) of CDDU among different intervals for the diagnosis of arterial ED. We included 357 patients who were under consideration for vascular ED.Results: We found significant differences in all the pairwise comparison of PSV in the 1st (0–5 min), 2nd (6–10 min), 3rd (11–15 min), and 4th (16–20 min) 4 intervals after the injection of prostaglandin E1 (p<0.001), except the 11–15 min vs. the 16–20 min interval (p=0.387). Using cavernosography, 294 patients were diagnosed with venous ED. Compared with other intervals, the diagnosis of CDDU 11–15 min after the intracavernous injection of 20 ug prostaglandin E1 (PGE1) had the best consistency with cavernosography (Kappa=0.761; p<0.001). Compared with other intervals, CDDU at 11–15 min had the highest specificity (93.65%), the highest Youden index (0.85), positive likelihood ratio of 14.46, positive predictive value of 98.54%, negative predictive value of 71.08% and a coincidence rate of 92.16%.Conclusions: Our findings support the increased utilization of CDDU for the diagnosis of both arterial and venous ED. The diagnosis at 11–15 min after intracavernous injection of PGE1 is accurate and stable, which would help to simplify the process and shorten the time of CDDU.

Ultrastructural Lesions Produced by Alcohol and Sucrose in the Heart and Liver of C57BL Mice

1970 ◽  
Vol 28 ◽  
pp. 208-209
Author(s):  
K.K. SEKHRI ◽  
C.S. ALEXANDER ◽  
H.T. NAGASAWA
Keyword(s):  
Osmium Tetroxide ◽  
Male Mice ◽  
Alcohol Group ◽  
Group Iii ◽  
Group I ◽  
C57bl Mice ◽  
Group Ii

C57BL male mice (Jackson Lab., Bar Harbor, Maine) weighing about 18 gms were randomly divided into three groups: group I was fed sweetened liquid alcohol diet (modified Schenkl) in which 36% of the calories were derived from alcohol; group II was maintained on a similar diet but alcohol was isocalorically substituted by sucrose; group III was fed regular mouse chow ad lib for five months. Liver and heart tissues were fixed in 2.5% cacodylate buffered glutaraldehyde, post-fixed in 2% osmium tetroxide and embedded in Epon-araldite.

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