Simvastatin down-regulates osteogenic response in cultured human aortic valve interstitial cells

Journal of Thoracic and Cardiovascular Surgery ◽

10.1016/j.jtcvs.2019.10.081 ◽

2019 ◽

Author(s):

Michael J. Jarrett ◽

Qingzhou Yao ◽

Neil Venardos ◽

Michael J. Weyant ◽

T. Brett Reece ◽

...

Keyword(s):

Aortic Valve ◽

Interstitial Cells ◽

Valve Interstitial Cells ◽

Osteogenic Response ◽

Human Aortic Valve

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Ligation of ICAM-1 on human aortic valve interstitial cells induces the osteogenic response: A critical role of the Notch1-NF-κB pathway in BMP-2 expression

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research ◽

10.1016/j.bbamcr.2014.07.017 ◽

2014 ◽

Vol 1843 (11) ◽

pp. 2744-2753 ◽

Author(s):

Dong Wang ◽

Qingchun Zeng ◽

Rui Song ◽

Lihua Ao ◽

David A. Fullerton ◽

...

Keyword(s):

Aortic Valve ◽

Critical Role ◽

Interstitial Cells ◽

Valve Interstitial Cells ◽

Osteogenic Response ◽

Human Aortic Valve

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Notch1 Promotes the Pro-Osteogenic Response of Human Aortic Valve Interstitial Cells via Modulation of ERK1/2 and Nuclear Factor-κB Activation

Arteriosclerosis Thrombosis and Vascular Biology ◽

10.1161/atvbaha.112.300912 ◽

2013 ◽

Vol 33 (7) ◽

pp. 1580-1590 ◽

Author(s):

Qingchun Zeng ◽

Rui Song ◽

Lihua Ao ◽

Michael J. Weyant ◽

Joon Lee ◽

...

Keyword(s):

Aortic Valve ◽

Nuclear Factor Κb ◽

Interstitial Cells ◽

Nuclear Factor ◽

Valve Interstitial Cells ◽

Osteogenic Response ◽

Human Aortic Valve

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Synergy between Sphingosine 1-Phosphate and Lipopolysaccharide Signaling Promotes an Inflammatory, Angiogenic and Osteogenic Response in Human Aortic Valve Interstitial Cells

PLoS ONE ◽

10.1371/journal.pone.0109081 ◽

2014 ◽

Vol 9 (10) ◽

pp. e109081 ◽

Author(s):

Isabel Fernández-Pisonero ◽

Javier López ◽

Esther Onecha ◽

Ana I. Dueñas ◽

Patricia Maeso ◽

...

Keyword(s):

Aortic Valve ◽

Interstitial Cells ◽

Valve Interstitial Cells ◽

Osteogenic Response ◽

Sphingosine 1 Phosphate ◽

Human Aortic Valve

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Matrix Gla-Protein Inhibits the TLR-4 Induced Osteogenic Response in Human Aortic Valve Interstitial Cells

Journal of the American College of Surgeons ◽

10.1016/j.jamcollsurg.2015.07.044 ◽

2015 ◽

Vol 221 (4) ◽

pp. S24-S25

Author(s):

Neil Venardos ◽

Thomas B. Reece ◽

Mike J. Weyant ◽

Xianzhong Meng ◽

David A. Fullerton

Keyword(s):

Aortic Valve ◽

Interstitial Cells ◽

Matrix Gla Protein ◽

Valve Interstitial Cells ◽

Osteogenic Response ◽

Human Aortic Valve

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3D Contractile Responses of Normal and Diseased Human Aortic Valve Interstitial Cells

Structural Heart ◽

10.1080/24748706.2021.1898250 ◽

2021 ◽

Vol 5 (sup1) ◽

pp. 1-1

Author(s):

Alex Khang ◽

Chiara Camillo ◽

Giovanni Ferrari ◽

Michael S. Sacks

Keyword(s):

Aortic Valve ◽

Interstitial Cells ◽

Contractile Responses ◽

Valve Interstitial Cells ◽

Human Aortic Valve

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Plasma from patients with calcified aortic disease triggers an osteoblast-like phenotype switch in human aortic valve interstitial cells

Atherosclerosis ◽

10.1016/j.atherosclerosis.2016.07.229 ◽

2016 ◽

Vol 252 ◽

pp. e234

Author(s):

L. Cattan-Lévy ◽

M.P. Jacob-Lenet ◽

M. Dehoux ◽

C. Deschildre ◽

I. Codogno ◽

...

Keyword(s):

Aortic Valve ◽

Aortic Disease ◽

Interstitial Cells ◽

Valve Interstitial Cells ◽

Phenotype Switch ◽

Human Aortic Valve

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The P38 Mitogen-Activated Protein Kinase Mediates Osteogenic Transformation Of Human Aortic Valve Interstitial Cells By Interleukin-1 Beta: Implications For Aortic Stenosis

Journal of Surgical Research ◽

10.1016/j.jss.2010.11.622 ◽

2011 ◽

Vol 165 (2) ◽

pp. 192-193

Author(s):

J.H. Lee ◽

X. Meng ◽

T.B. Reece ◽

M.J. Weyant ◽

J.C. Cleveland ◽

...

Keyword(s):

Protein Kinase ◽

Aortic Valve ◽

Aortic Stenosis ◽

Interleukin 1 ◽

Interstitial Cells ◽

Mitogen Activated Protein Kinase ◽

Interleukin 1 Beta ◽

Valve Interstitial Cells ◽

Mitogen Activated Protein ◽

Human Aortic Valve

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Phospholipids accumulation and calcification in cultured primary human aortic valve interstitial cells: New insights revealed by confocal Raman imaging

Journal of Raman Spectroscopy ◽

10.1002/jrs.5760 ◽

2019 ◽

Vol 51 (1) ◽

pp. 104-114

Author(s):

Krzysztof Czamara ◽

Magdalena Kopytek ◽

Malgorzata Szulczewska ◽

Agnieszka Kaczor ◽

Joanna Natorska

Keyword(s):

Aortic Valve ◽

Interstitial Cells ◽

Raman Imaging ◽

Valve Interstitial Cells ◽

Confocal Raman ◽

Human Aortic Valve

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Matrix Gla protein negatively regulates calcification of human aortic valve interstitial cells isolated from calcified aortic valves

Proceedings for Annual Meeting of The Japanese Pharmacological Society ◽

10.1254/jpssuppl.92.0_1-p-064 ◽

2019 ◽

Vol 92 (0) ◽

pp. 1-P-064

Author(s):

Seya Kazuhiko ◽

Zaiqiang Yu ◽

Mari Chiyoya ◽

Wei Yang ◽

Kazuyuki Daitoku ◽

...

Keyword(s):

Aortic Valve ◽

Interstitial Cells ◽

Matrix Gla Protein ◽

Aortic Valves ◽

Valve Interstitial Cells ◽

Human Aortic Valve

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Interleukin-1 beta mediates a phenotypic change in human aortic valve interstitial cells: Implications for calcific aortic stenosis

Journal of the American College of Surgeons ◽

10.1016/j.jamcollsurg.2010.06.071 ◽

2010 ◽

Vol 211 (3) ◽

pp. S30

Author(s):

Joon Ho Lee ◽

Winston P. Choi ◽

Michael J. Weyant ◽

Joseph C. Clevel ◽

Xianzhong Meng ◽

...

Keyword(s):

Aortic Valve ◽

Aortic Stenosis ◽

Interleukin 1 ◽

Interstitial Cells ◽

Phenotypic Change ◽

Interleukin 1 Beta ◽

Calcific Aortic Stenosis ◽

Valve Interstitial Cells ◽

Human Aortic Valve

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