scholarly journals Selenium enhances the expression of miR-9, miR-124 and miR-29a during neural differentiation of bone marrow mesenchymal stem cells

Author(s):  
Hanieh Jalali ◽  
Hasti Golchin ◽  
Zahra Sadri ◽  
Latifeh Karimzadeh Bardei ◽  
Mohammad Nabiuni
2008 ◽  
Vol 22 (4) ◽  
pp. 995-1001 ◽  
Author(s):  
Shabnam Kermani ◽  
Khadijeh Karbalaie ◽  
Seyed Hossein Madani ◽  
Ali Akbar Jahangirnejad ◽  
Mohamadreza Baghaban Eslaminejad ◽  
...  

2014 ◽  
Vol 998-999 ◽  
pp. 238-242 ◽  
Author(s):  
Yan Sheng Liao ◽  
Li Deng ◽  
Xiao Qing Gao ◽  
Chao Xian Yang

Objective: To establish composite culture system of rat bone marrow mesenchymal stem cells (BMSCs) and self-assembling peptide hydrogel RADA16-І, and to investigate the effect of RADA16-І hydrogel on neural differentiation of BMSCs. Methods: BMSCs were isolated, cultivated and labeled with green fluorescent protein (GFP), then they were inoculated on glass coverslips or in RADA16-І solution to form control group and RADA16-І group respectively. The morphological changes of BMSCs induced by neural induction medium were observed, and GFAP, NeuN and Map-2 expressions of BMSCs in each group were detected with immunofluorescence. Results: The induced BMSCs presented neuron-like change, and the rates of GFAP and NF-200 positive cells in RADA16-І group were higher than that in control group (P < 0.05). Conclusion: Self-assembling peptide RADA16-І hydrogel can promote neural differentiation of BMSCs, and which may be used as scaffold material on BMSCs transplantation for treatment of nervous system diseases.


2014 ◽  
Vol 38 (11) ◽  
pp. 1337-1343 ◽  
Author(s):  
Yanfei Li ◽  
Cuiqin Wang ◽  
Guangyu Zhang ◽  
Xiaohan Wang ◽  
Ranran Duan ◽  
...  

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