1567 COMPARISON OF HEALTH RELATED QUALITY OF LIFE BETWEEN HORMONE THERAPY AND RADICAL PROSTATECTOMY FOR CLINICALLY LOCALIZED AND LOCALLY ADVANCED PROSTATE CANCER IN JAPANESE MALES

2010 ◽  
Vol 183 (4S) ◽  
Author(s):  
Kenji Nishimura ◽  
Tetsuji Soda ◽  
Kazuyuki Yamanaka ◽  
Toshiyuki Hirai ◽  
Hidefumi Kishikawa ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Advanced Prostate Cancer ◽  
Locally Advanced ◽  
Health Related Quality ◽  
Locally Advanced Prostate Cancer ◽  
Related Quality ◽  
Health Related

Comparison of Health Related Quality of Life between Hormone Therapy and Radical Prostatectomy for Clinically Localized and Locally Advanced Prostate Cancer in Japanese Males

2008 ◽  
Vol 2 (3) ◽  
pp. 150-156
Author(s):  
Kenji Nishimura ◽  
Yasuyuki Kobayashi ◽  
Taigo Kato ◽  
Shigeki Tokugawa ◽  
Hidefumi Kishikawa ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Advanced Prostate Cancer ◽  
Locally Advanced ◽  
Health Related Quality ◽  
Locally Advanced Prostate Cancer ◽  
Related Quality ◽  
Health Related

Health-Related Quality of Life After the Diagnosis of Locally Advanced or Advanced Prostate Cancer

2017 ◽  
Vol 40 (5) ◽  
pp. 412-419 ◽  
Author(s):  
Leah Zajdlewicz ◽  
Melissa K. Hyde ◽  
Stephen J. Lepore ◽  
Robert A. Gardiner ◽  
Suzanne K. Chambers
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Advanced Prostate Cancer ◽  
Locally Advanced ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

scholarly journals Health-Related Quality of Life following Cytoreductive Radical Prostatectomy in Patients with de-novo Oligometastatic Prostate Cancer

Cancers ◽  
2021 ◽  
Vol 13 (22) ◽  
pp. 5636
Author(s):  
Michael Chaloupka ◽  
Lina Stoermer ◽  
Maria Apfelbeck ◽  
Alexander Buchner ◽  
Vera Wenter ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
De Novo ◽  
Health Related Quality ◽  
Significant Difference ◽  
Related Quality ◽  
Health Related

(1) Background: local treatment of the primary tumor has become a valid therapeutic option in de-novo oligo-metastatic prostate cancer (PC). However, evidence regarding radical prostatectomy (RP) in this setting is still subpar, and the effect of cytoreductive RP on postoperative health-related quality of life (HRQOL) is still unclear. (2) Methods: for the current study, patients with de-novo oligo-metastatic PC (cM1-oligo), defined as ≤5 bone lesions in the preoperative staging, were included, and matched cohorts using the variables age, body-mass index (BMI), and pT-stage were generated. Patient-reported outcome measures (PROMS) were assessed pre- and postoperatively using the validated EORTC-QLQ-C30, IIEF-5, and ICIQ-SF questionnaires. The primary endpoint for univariate and multivariable analysis was good general HRQOL defined by previously validated cut-off values. (3) Results: in total, 1268 patients (n = 84 (7%) cM1-oligo) underwent RP between 2012 and 2020 at one tertiary care center. A matched cohort of 411 patients (n = 79 with oligo-metastatic bone disease (cM1-oligo) and n = 332 patients without clinical indication of metastatic disease (cM0)) was created. The median follow-up was 25mo. There was no significant difference in good general HRQOL rates between cM1-oligo-patients and cM0-patients before RP (45.6% vs. 55.2%, p = 0.186), and at time of follow-up (44% vs. 56%, p = 0.811). Global health status (GHS) worsened significantly in cM0-patients compared to baseline (−5, p = 0.001), whereas GHS did not change significantly in cM1-oligo-patients (+3.2, p = 0.381). In multivariate analysis stratified for good erectile function (IIEF5 > 18; OR 5.722, 95% CI 1.89–17.36, p = 0.002) and continence recovery (OR 1.671, 95% CI 1.03–2.70, p = 0.036), cM1-oligo was not an independent predictive feature for general HRQOL (OR 0.821, 95% CI 0.44–1.53, p = 0.536). (4) Conclusions: in this large contemporary retrospective analysis, we observed no significant difference in HRQOL in patients with the oligometastatic bone disease after cytoreductive radical prostatectomy, when compared to patients with localized disease at time of surgery.

scholarly journals Incontinence and Erectile Dysfunction Following Radical Prostatectomy: A Review

2005 ◽  
Vol 5 ◽  
pp. 747-758 ◽  
Author(s):  
Gerasimos Alivizatos ◽  
Andreas Skolarikos
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Erectile Dysfunction ◽  
Radical Prostatectomy ◽  
Surgical Technique ◽  
Localized Prostate Cancer ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Radical prostatectomy remains the treatment of choice for localized prostate cancer in age-appropriate and health-appropriate men. Although cancer control is the most important aspect of a radical prostatectomy, minimization of postoperative morbidity, especially urinary incontinence and erectile dysfunction, is becoming a greater concern. We reviewed recent data available on Medline regarding the incidence, pathophysiology, evaluation, and treatment of incontinence and sexual dysfunction after radical prostatectomy. Health-related quality of life issues have been specifically addressed. Although low incidences of incontinence and erectile dysfunction after radical prostatectomy have been reported in the hands of experienced surgeons, the literature review revealed a great variety, with incontinence rates ranging from 0.3–65.6% and potency rates ranging from 11–87%. Several factors contribute to this wide difference, the most important being the application of a meticulous surgical technique. General and cancer-specific health-related quality of life is not being affected after radical prostatectomy. The incidence of incontinence and erectile dysfunction is higher after radical prostatectomy when compared to the incidence observed when other therapies for localized prostate cancer are applied. However, the majority of the patients undergoing radical prostatectomy would vote for the operation again. Today, avoidance of major complications after radical prostatectomy depends mostly on a high-quality surgical technique. When incontinence or erectile dysfunction persists after radical prostatectomy, the majority of the treated patients can be managed effectively by various methods.

scholarly journals Health-related quality of life (HRQoL) outcomes in men treated with laparoscopic radical prostatectomy (LRP) for localised prostate cancer

2014 ◽  
Vol 12 ◽  
pp. S107
Author(s):  
Ahmed Abroaf ◽  
Kimberley Edwards ◽  
Ameet Patel ◽  
N. Brown ◽  
Naeem Soomro ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Laparoscopic Radical Prostatectomy ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related
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