PGI36 Relationship Between Clinical Severity and Health Related Quality of Life in Chronic Liver Diseases

We sought to examine the influence of hand grip strength (HGS) and skeletal muscle mass (SMM) on the health-related quality of life (H-QOL) as evaluated by the 36-Item Short-Form Health Survey (SF-36) questionnaire in chronic liver diseases (CLDs, 198 men and 191 women). Decreased HGS was defined as HGS <26 kg for men and <18 kg for women. Decreased SMM was defined as SMM index <7.0 kg/m2 for men and <5.7 kg/m2 for women, using bioimpedance analysis. SF-36 scores were compared between groups stratified by HGS or SMM. Between-group differences (decreased HGS vs. non-decreased HGS) in the items of physical functioning (PF), role physical (RP), bodily pain, vitality (VT), social functioning (SF), role emotional (RE), and physical component summary score (PCS) reached significance, while between-group differences (decreased SMM vs. non-decreased SMM) in the items of PF, SF and RE were significant. Multivariate analyses revealed that HGS was significantly linked to PF (p = 0.0031), RP (p = 0.0185), and PCS (p = 0.0421) in males, and PF (p = 0.0034), VT (p = 0.0150), RE (p = 0.0422), and PCS (p = 0.0191) in females. HGS had a strong influence especially in the physiological domains in SF-36 in CLDs.

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Health-related quality of life in chronic liver disease: the impact of type and severity of disease

The American Journal of Gastroenterology ◽

10.1111/j.1572-0241.2001.03956.x ◽

2001 ◽

Vol 96 (7) ◽

pp. 2199-2205 ◽

Cited By ~ 184

Author(s):

Zobair M Younossi ◽

Navdeep Boparai ◽

Lori Lyn Price ◽

Michelle L Kiwi ◽

Marilyn McCormick ◽

...

Keyword(s):

Quality Of Life ◽

Liver Disease ◽

Chronic Liver Disease ◽

Chronic Liver ◽

Health Related Quality ◽

Severity Of Disease ◽

Related Quality ◽

Health Related ◽

The Impact

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Association between Clinical Signs of Oral Lichen Planus and Oral Health-Related Quality of Life: A Preliminary Study

Dentistry Journal ◽

10.3390/dj8040113 ◽

2020 ◽

Vol 8 (4) ◽

pp. 113

Author(s):

Sasirin Yiemstan ◽

Sudaduang Krisdapong ◽

Pornpan Piboonratanakit

Keyword(s):

Quality Of Life ◽

Oral Health ◽

Oral Lichen Planus ◽

Clinical Severity ◽

Health Related Quality ◽

Related Quality ◽

Health Related ◽

Oral Lichen ◽

Oral Impacts

Subjective patient’s symptoms and Oral Health-Related Quality of Life (OHRQoL) are recommended to be involved in oral lichen planus (OLP) studies. This study aims to assess the OHRQoL of OLP patients, and their associations with pain and OLP in Thai patients. Sixty-nine patients were interviewed using the Numeric Rating Scale (NRS) for pain perception and Oral Impacts on Daily Performance (OIDP) index. OLP signs examined included localization, types, number of affected sides and clinical severity using the Thongprasom sign scoring system. There were significant associations (rs = 0.490, p < 0.001) between clinical severity and the intensity of oral impacts as well as pain (rs = 0.298, p = 0.013). The intensity of oral impacts and pain increased according to the increasing OLP clinical severity, except for the white striae lesions (Thongprasom sign score 1). The erosive/ulcerative OLP lesions (Thongprasom sign scores 4 and 5) were the most painful symptom and had the highest degree of oral impacts (p < 0.001). No significant associations were found between the number of affected lesion sides and OHRQoL (p = 0.316) and pain (p = 0.284). OHRQoL was associated with OLP type and clinical severity but not with the number of affected sides.

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