scholarly journals Cost Saving Study Of Five Grass Pollen Slit Tablet Versus Scit’s & Symptomatic Treatment

2015 ◽  
Vol 18 (7) ◽  
pp. A497
Author(s):  
M Tatar ◽  
A Senturk ◽  
E Tuna ◽  
S Darrigol ◽  
L Girard ◽  
...  
Author(s):  
Bernd Brüggenjürgen ◽  
Ludger Klimek ◽  
Thomas Reinhold

Abstract Purpose Real-world evidence (RWE) with regard to allergen-specific immunotherapy (AIT) adherence is increasingly available. Economic modelling has already shown AIT to be cost-effective in the treatment of allergic rhinitis compared with symptomatic treatment. However, analyzing sublingual (SLIT) and subcutaneous (SCIT) immunotherapeutic approaches based on RWE adherence data are not available for Germany. This analysis outlines the cost-effectiveness of SCIT compared with SLIT as well as a symptomatic treatment modality on the basis of recent RWE adherence data. Methods A Markov model, with predefined disease stages and a time period of 9 years, was adapted for this analysis. A 6-grass subcutaneous allergoid SCIT preparation and a 5-grass pollen SLIT tablet was employed as AIT administrations. Quality-adjusted life years (QALYs) were calculated based on symptom scores and used as the effectiveness variable. Total costs and cost effectiveness of SCIT, SLIT and symptomatic treatment (ST) were calculated. Model uncertainties were estimated by means of additional sensitivity analyses. Applied discount rate was 3%. Results Both SCIT and SLIT preparations proved superior compared to symptomatic treatment with regard to effectiveness. Although more expensive, AIT also proved to be cost-effective. A direct comparison of SCIT (Allergovit®) and SLIT (Oralair®) showed lower total costs for SCIT treatment over the study period of 9 years (SCIT 1779 € versus SLIT 2438 €) and improved effectiveness (SCIT 7.17 QALYs versus SLIT 7.11 QALYs). Conclusion AIT represents a cost-effective treatment option for patients with allergic rhinitis compared with symptomatic treatment. SCIT appeared to be dominant and cost-effective, due in particular to higher patient adherence and lower drug costs.


2003 ◽  
Vol 1 (4) ◽  
pp. 273-278 ◽  
Author(s):  
Marco Romano ◽  
Riccardo Marmo ◽  
Antonio Cuomo ◽  
Teresa De Simone ◽  
Caterina Mucherino ◽  
...  

2018 ◽  
Vol 6 (1) ◽  
pp. 61-74
Author(s):  
Umi Salamah ◽  
Herlawati Herlawati

Abstract Rahayu Printing is a business entity that provides merchandising services such as wedding invitations, circumcision invitations, business cards, notes, letterhead, yasin and others. Based on sales that have been achieved so far, Rahayu Printing felt not satisfied with the results obtained and trying to increase sales and service through online sales system. Sales that go so far encounter obstacles in the process of marketing from consumers to consumers, the sale of goods still use a system of sales in the form of book-shaped catalogs, very tight competition, locations adjacent to other printing, and constraints from distance and time to obtain information on shopping in printing . It makes the sale less cost saving, energy and time because the system used still manually. The method used in the design of information systems sales of goods is waterfall method. From the manufacture of web-based goods sales system, is expected to solve the existing constraints, simplify, accelerate the sales system and hopefully can increase profits on the sale of goods Rahayu Bekasi Printing.   Keywords: Goods, Information, Sales, Printing, Waterfall.                                                                   Abstrak                                                                  Percetakan Rahayu merupakan sebuah badan usaha yang menyediakan jasa penjualan barang seperti undangan pernikahan, undangan khitanan, kartu nama, nota, kop surat, yasin dan lain-lain. Berdasarkan hasil penjualan yang telah dicapai selama ini, Percetakan Rahayu merasa belum puas dengan hasil yang didapat dan berupaya ingin meningkatkan penjualan serta pelayanan melalui sistem penjualan secara online. Penjualan yang berlangsung selama ini menemui kendala dalam proses pemasaran dari konsumen ke konsumen, penjualan barang masih menggunakan sistem penjualan berupa katalog berbentuk buku, persaingan yang sangat ketat, lokasi yang berdekatan dengan percetakan lainnya, serta kendala dari jarak dan waktu untuk mendapatkan informasi belanja di percetakan. Hal tersebut membuat penjualan kurang menghemat biaya, tenaga dan waktu karena sistem yang digunakan masih secara manual. Metode yang digunakan pada perancangan sistem informasi penjualan barang tersebut adalah metode waterfall. Dari pembuatan sistem penjualan barang berbasis web, diharapkan dapat memecahkan kendala yang ada, mempermudah, mempercepat sistem penjualan dan semoga dapat meningkatkan keuntungan penjualan barang pada Percetakan Rahayu Bekasi.   Kata kunci: Barang, Informasi, Penjualan, Percetakan, Waterfall.


Sign in / Sign up

Export Citation Format

Share Document