scholarly journals PIN19 A COST EFFECTIVENESS ANALYSIS OF ACTIVE CASE FINDING AND PASSIVE CASE FINDING FOR CASE DETECTION OF TUBERCULOSIS AT KISUGU HC III,KAMPALA UGANDA.

2020 ◽  
Vol 23 ◽  
pp. S171-S172
Author(s):  
M. Muhoozi ◽  
J. Tusabe ◽  
L. Tabwenda ◽  
S.M. Jimale
2021 ◽  
Vol 25 (3) ◽  
pp. 171-181
Author(s):  
H. Sohn ◽  
S. Sweeney ◽  
D. Mudzengi ◽  
J. Creswell ◽  
N. A. Menzies ◽  
...  

Active case-finding (ACF) is an important component of the End TB Strategy. However, ACF is resource-intensive, and the economics of ACF are not well-understood. Data on the costs of ACF are limited, with little consistency in the units and methods used to estimate and report costs. Mathematical models to forecast the long-term effects of ACF require empirical measurements of the yield, timing and costs of case detection. Pragmatic trials offer an opportunity to assess the cost-effectiveness of ACF interventions within a ‘real-world´ context. However, such analyses generally require early introduction of economic evaluations to enable prospective data collection on resource requirements. Closing the global case-detection gap will require substantial additional resources, including continued investment in innovative technologies. Research is essential to the optimal implementation, cost-effectiveness, and affordability of ACF in high-burden settings. To assess the value of ACF, we must prioritize the collection of high-quality data regarding costs and effectiveness, and link those data to analytical models that are adapted to local settings.


PLoS ONE ◽  
2019 ◽  
Vol 14 (7) ◽  
pp. e0210919 ◽  
Author(s):  
Sovannary Tuot ◽  
Alvin Kuo Jing Teo ◽  
Danielle Cazabon ◽  
Say Sok ◽  
Mengieng Ung ◽  
...  

Author(s):  
Shifa Habib ◽  
Kiran Azeemi ◽  
S. M. Asad Zaidi ◽  
Wafa Jamal ◽  
Talha Kazmi ◽  
...  

2012 ◽  
Vol 6 (9) ◽  
pp. e1818 ◽  
Author(s):  
Charles Ezenduka ◽  
Erik Post ◽  
Steven John ◽  
Abdulkarim Suraj ◽  
Abdulahi Namadi ◽  
...  

2014 ◽  
Vol 90 (5) ◽  
pp. 866-872 ◽  
Author(s):  
Rajendra P. Yadav ◽  
Nobuyuki Nishikiori ◽  
Peou Satha ◽  
Mao T. Eang ◽  
Yoel Lubell

2017 ◽  
Vol 145 (6) ◽  
pp. 1107-1117 ◽  
Author(s):  
L. SHAH ◽  
M. ROJAS ◽  
O. MORI ◽  
C. ZAMUDIO ◽  
J. S. KAUFMAN ◽  
...  

SUMMARYWe compared the cost-effectiveness (CE) of an active case-finding (ACF) programme for household contacts of tuberculosis (TB) cases enrolled in first-line treatment to routine passive case-finding (PCF) within an established national TB programme in Peru. Decision analysis was used to model detection of TB in household contacts through: (1) self-report of symptomatic cases for evaluation (PCF), (2) a provider-initiated ACF programme, (3) addition of an Xpert MTB/RIF diagnostic test for a single sputum sample from household contacts, and (4) all strategies combined. CE was calculated as the incremental cost-effectiveness ratio (ICER) in terms of US dollars per disability-adjusted life years (DALYs) averted. Compared to PCF alone, ACF for household contacts resulted in an ICER of $2155 per DALY averted. The addition of the Xpert MTB/RIF diagnostic test resulted in an ICER of $3275 per DALY averted within a PCF programme and $3399 per DALY averted when an ACF programme was included. Provider-initiated ACF of household contacts in an urban setting of Lima, Peru can be highly cost-effective, even including costs to seek out contacts and perform an Xpert/MTB RIF test. ACF including Xpert MTB/RIF was not cost-effective if TB cases detected had high rates of default from treatment or poor outcomes.


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