Patient-Derived Xenograft Tumor Models: Overview and Relevance to IR

Journal of Vascular and Interventional Radiology ◽

10.1016/j.jvir.2018.01.782 ◽

2018 ◽

Vol 29 (6) ◽

pp. 880-882.e1 ◽

Author(s):

Rahul A. Sheth ◽

Nicholas Perkons ◽

Eleonora Dondossola ◽

Sumit K. Subudhi ◽

Terence P. Gade ◽

...

Keyword(s):

Xenograft Tumor ◽

Tumor Models ◽

Patient Derived Xenograft

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Enhanced anti-tumor efficacy of IL-7/CCL19-producing human CAR-T cells in orthotopic and patient-derived xenograft tumor models

Cancer Immunology Immunotherapy ◽

10.1007/s00262-021-02853-3 ◽

2021 ◽

Author(s):

Shunsuke Goto ◽

Yukimi Sakoda ◽

Keishi Adachi ◽

Yoshitaka Sekido ◽

Seiji Yano ◽

...

Keyword(s):

T Cells ◽

Xenograft Tumor ◽

Tumor Models ◽

Car T Cells ◽

Patient Derived Xenograft ◽

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Abstract 646: Feasibility of assessing circulating tumor cells in patient-derived xenograft tumor models

10.1158/1538-7445.am2016-646 ◽

2016 ◽

Author(s):

Somdutta Roy ◽

Kevin Martinez ◽

Arturo Ramirez ◽

Daniel Campton ◽

Joshua Nordberg ◽

...

Keyword(s):

Tumor Cells ◽

Circulating Tumor Cells ◽

Xenograft Tumor ◽

Tumor Models ◽

Patient Derived Xenograft

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Abstract P1-03-06: Development of patient-derived xenograft tumor models and 3D spheroid culture from advanced hormone receptor-positive inflammatory breast cancer patients for evaluation of new therapeutics

10.1158/1538-7445.sabcs19-p1-03-06 ◽

2020 ◽

Author(s):

Wenan Qiang ◽

Zhangfeng Zhong ◽

Pamela Monahan ◽

Kristy Tse ◽

Youbin Zhang ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Patients ◽

Inflammatory Breast Cancer ◽

Hormone Receptor ◽

Xenograft Tumor ◽

Breast Cancer Patients ◽

Tumor Models ◽

Spheroid Culture ◽

Hormone Receptor Positive ◽

Patient Derived Xenograft

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Abstract 2739: Genetic characterization of an extensive panel of patient-derived xenograft tumor models of hepatocellular carcinoma for preclinical development.

10.1158/1538-7445.am2013-2739 ◽

2013 ◽

Author(s):

Douglas D. Fang ◽

Qiang Xu ◽

Yexiong Tan ◽

Lei Chen ◽

Hongye Sun ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Genetic Characterization ◽

Xenograft Tumor ◽

Tumor Models ◽

Preclinical Development ◽

Patient Derived Xenograft

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Abstract 4367: Discovery and evaluation of pharmacodynamic and predictive biomarkers for anti-RSPO3, a treatment that reduces tumor growth and cancer stem cell frequency in patient derived xenograft tumor models

10.1158/1538-7445.am2015-4367 ◽

2015 ◽

Author(s):

Fiore Cattaruzza ◽

Pete Yeung ◽

Wan-Ching Yen ◽

Alayne Brunner ◽

Min Wang ◽

...

Keyword(s):

Stem Cell ◽

Cancer Stem Cell ◽

Tumor Growth ◽

Predictive Biomarkers ◽

Xenograft Tumor ◽

Tumor Models ◽

Cell Frequency ◽

Patient Derived Xenograft

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Abstract 688: Activating JAK1-S703I mutation may predict the sensitivity of JAK-STAT inhibition in hepatocellular carcinoma patient-derived xenograft tumor models

10.1158/1538-7445.am2015-688 ◽

2015 ◽

Author(s):

Shuqun Yang ◽

Chonglin Luo ◽

Qingyang Gu ◽

Qiang Xu ◽

Hongye Sun ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Xenograft Tumor ◽

Tumor Models ◽

Patient Derived Xenograft ◽

Carcinoma Patient

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Abstract 1046: Developing patient-derived xenograft tumor models that recapture clinical manifestation of inflammatory breast cancer patients

10.1158/1538-7445.am2018-1046 ◽

2018 ◽

Author(s):

Wenan Qiang ◽

Youbin Zhang ◽

Demirkan Gursel Gursel ◽

Jian-Jun Wei ◽

Charles David James ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Patients ◽

Clinical Manifestation ◽

Inflammatory Breast Cancer ◽

Xenograft Tumor ◽

Breast Cancer Patients ◽

Tumor Models ◽

Patient Derived Xenograft

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Abstract 1212: Studying cancer drug resistance in patient derived xenograft tumor models

10.1158/1538-7445.am2014-1212 ◽

2014 ◽

Author(s):

Tengfei Yu ◽

Ying Yan ◽

Wei Du ◽

Yuefei Yang ◽

Tingting Tan ◽

...

Keyword(s):

Drug Resistance ◽

Cancer Drug ◽

Xenograft Tumor ◽

Tumor Models ◽

Cancer Drug Resistance ◽

Patient Derived Xenograft

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Abstract 2839: Antitumor activities of FGFR inhibitors in FGFR1-overexpressing hepatocellular carcinoma patient-derived xenograft tumor models

10.1158/1538-7445.am2014-2839 ◽

2014 ◽

Author(s):

Douglas D. Fang ◽

Bin Zhang ◽

Weiguo Xu ◽

Kang Yan ◽

Qingyang Gu ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Xenograft Tumor ◽

Antitumor Activities ◽

Tumor Models ◽

Patient Derived Xenograft ◽

Carcinoma Patient

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Abstract 1056: Potentin vivoanti-tumor activity of D-1553 as a single agent and in combination with targeted therapeutics in a broad spectrum of patient-derived xenograft tumor models with KRas G12C mutation

10.1158/1538-7445.am2021-1056 ◽

2021 ◽

Author(s):

Zhe Shi ◽

Jifang Weng ◽

Xiaochong Fan ◽

Qingqing Zhu ◽

Emily Robb ◽

...

Keyword(s):

Broad Spectrum ◽

Single Agent ◽

Targeted Therapeutics ◽

Xenograft Tumor ◽

Tumor Models ◽

Patient Derived Xenograft

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