Deep Vein Thrombosis: Final Report of the Prospective Multicenter Pearl Registry on Endovascular Treatment

Background: The risk of complications and discomfort in patients who undergo prolonged infusion of a thrombolytic agent is significant when conventional catheter-directed thrombolysis is used to treat lower extremity deep vein thrombosis (DVT). Purpose: To evaluate the feasibility and safety of single-session endovascular treatment for symptomatic lower extremity DVT. Material and Methods: Single-session endovascular treatment for lower extremity DVT was performed on 29 limbs in 26 patients diagnosed with acute DVT in our institution. Nine patients were male and 17 female, with a mean age of 64 years (range 28–82 years). At 5–10 min after the locoregional injection of the thrombolytic agent (urokinase) via a 5-Fr catheter to soften the thrombus, aspiration thrombectomy was performed with a large-bore sheath. In patients with an underlying anatomical stenosis or obstruction, combined angioplasty with or without stent placement was performed immediately after the complete removal of the thrombus. We then evaluated the technical and clinical outcomes of the procedure, along with any complications or recurrences of DVT. Results: Technical success was achieved in 24 procedures (82.8%) of single-session endovascular treatment for lower extremity DVT, and clinical success was achieved in 22 (75.9%) of these single-session procedures. Additional catheter-directed thrombolysis procedures were performed on five limbs after repeated aspiration thrombectomies failed to completely remove thrombi in those limbs. Stenotic or occlusive lesions were revealed in 24 limbs and percutaneous angioplasty procedures with or without stent placement were performed in these cases. No major complications resulted from the procedure. Conclusion: Single-session endovascular treatment is a feasible technique that provides acceptable technical and clinical success with excellent safety for treating symptomatic lower extremity DVT.

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OP-151 Catheter-directed Thrombolysis and Endovascular Treatment in Lower Extremity Deep Vein Thrombosis

The American Journal of Cardiology ◽

10.1016/j.amjcard.2015.01.302 ◽

2015 ◽

Vol 115 ◽

pp. S66

Author(s):

Kemal Karaarslan ◽

Gökhan Albayrak ◽

Burçin Abud ◽

Mahir Yıldırım ◽

Mustafa Karaçelik ◽

...

Keyword(s):

Deep Vein Thrombosis ◽

Lower Extremity ◽

Endovascular Treatment ◽

Vein Thrombosis ◽

Catheter Directed Thrombolysis ◽

Deep Vein

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Endovascular treatment of acute limb ischemia and proximal deep vein thrombosis using rotational thrombectomy: A review of published literature

Cardiovascular Revascularization Medicine ◽

10.1016/j.carrev.2013.08.005 ◽

2013 ◽

Vol 14 (6) ◽

pp. 343-348 ◽

Cited By ~ 16

Author(s):

Michael Lichtenberg ◽

Friedrich-Wilhelm Stahlhoff ◽

Dirk Boese

Keyword(s):

Deep Vein Thrombosis ◽

Endovascular Treatment ◽

Limb Ischemia ◽

Proximal Deep Vein Thrombosis ◽

Acute Limb Ischemia ◽

Vein Thrombosis ◽

Rotational Thrombectomy ◽

Deep Vein

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The results of aspiration thrombecomy in the endovascular treatment for iliofemoral deep vein thrombosis

Journal of the Korean Surgical Society ◽

10.4174/jkss.2013.84.5.292 ◽

2013 ◽

Vol 84 (5) ◽

pp. 292

Author(s):

Jae Hoon Lee ◽

Woo Hyung Kwun ◽

Bo Yang Suh

Keyword(s):

Deep Vein Thrombosis ◽

Endovascular Treatment ◽

Vein Thrombosis ◽

Deep Vein

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Application of manual aspiration thrombectomy in the treatment of deep vein thrombosis in cancer patients: Descriptive retrospective cohort study

PLoS ONE ◽

10.1371/journal.pone.0255539 ◽

2021 ◽

Vol 16 (8) ◽

pp. e0255539

Author(s):

Eu Hyun Kim ◽

Hae Giu Lee ◽

Jung Suk Oh ◽

Ho Jong Chun ◽

Byung Gil Choi ◽

...

Keyword(s):

Cohort Study ◽

Deep Vein Thrombosis ◽

Endovascular Treatment ◽

Cancer Patients ◽

Balloon Angioplasty ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Aspiration Thrombectomy ◽

Vein Thrombosis ◽

Deep Vein

Objectives To determine the outcomes and feasibility of endovascular treatment, mainly based on manual aspiration thrombectomy (MAT) with adjunctive percutaneous balloon angioplasty with or without stent deployment, for treatment of symptomatic ilio-femoral deep vein thrombosis (IFDVT) in cancer patients. Materials and methods In this retrospective cohort study, 135 consecutive patients (56 men; mean age, 63 years; 149 limbs) with acute (n = 113; 83.7%) and subacute to chronic (n = 22; 16.3%) symptomatic IFDVT underwent MAT-based endovascular treatment. Among them, adjunctive balloon angioplasty and stent placement was performed in 94 patients. Technical and clinical success regarding stage and cause of DVT was assessed. Results Technical success (complete thrombus removal without residual thrombus or stenosis) was achieved in 89.6%, and subjective symptom improvement was stated by 71.5% of treated patients. The primary patency rates were 88.1%, 81.6%, 76.0%, 74.1% and 69.1% at 1, 3, 6, 12, and 30 months, respectively. Recurrent IFDVT occurred in 19.3% (26/135) of patients, 0.79 cases per patients-years of follow up. According to the analysis by causes of IFDVT, recurrence rate was 19.3% (11/57), 21.2% (12/57), and 14.3% (3/21) in unknown, compression/invasion of the vein by cancerous mass, and May-Thurner syndrome groups, respectively (p = 0.798). No procedure-related complication developed. Conclusions Endovascular treatment based on MAT is a feasible treatment option with favorable outcomes and minimal risk of complication in cancer patients with symptomatic IFDVT.

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