The EORTC QLQ-C30 and QLQ-CR29 may play a complementary role to LARS score in evaluating the quality of life for patients following laparoscopic and robotic rectal cancer surgery

Purpose To identify factors affecting the quality of life (QoL) of disease-free survivors of rectal cancer. Patients and Methods One hundred twenty-one patients in complete remission more than 2 years after diagnosis were asked to complete three QoL questionnaires: the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30; its colorectal module, QLQ-CR38; and the Duke generic instrument. Results Patients reported less pain (P = .002) than did controls drawn from the general population. EORTC QLQ-C30 physical scores were also higher among rectal cancer survivors than in the general Norwegian or German population (P = .0005 and P = .002, respectively). Unexpectedly, stoma patients reported better social functioning than did nonstoma patients (P = .005), with less anxiety (P = .008) and higher self-esteem (P = .0002). In the present authors' experience, the QLQ-CR38 does not discriminate between these groups. Residual abdominal or pelvic pain and constipation had the most negative influence on QoL. Conclusion QoL is high among rectal cancer survivors, including stoma patients. Simultaneous use of several QoL questionnaires appears to have value in follow-up and in monitoring the effects of therapy. The impact of residual pain and constipation on long-term QoL should be considered when establishing a treatment regimen.

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Comparison of quality of life outcomes between laparoscopic and open approach for rectal cancer surgery

Southern Clinics of Istanbul Eurasia ◽

10.14744/scie.2020.99705 ◽

2021 ◽

Author(s):

selçuk kaya

Keyword(s):

Quality Of Life ◽

Rectal Cancer ◽

Cancer Surgery ◽

Rectal Cancer Surgery ◽

Open Approach ◽

Life Outcomes ◽

Quality Of Life Outcomes

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Quality of life after rectal cancer surgery (systematic review)

Koloproktologia ◽

10.33878/2073-7556-2021-20-1-59-67 ◽

2021 ◽

Vol 20 (1) ◽

pp. 59-67

Author(s):

A. B. Serebriy ◽

E. A. Khomyakov ◽

I. O. Nafedzov ◽

O. Yu. Fomenko ◽

E. G. Rybakov

Keyword(s):

Quality Of Life ◽

Risk Factors ◽

Rectal Cancer ◽

Anterior Resection ◽

Low Anterior Resection ◽

Life Quality ◽

Cancer Surgery ◽

Rectal Cancer Surgery ◽

Low Anterior Resection Syndrome

Aim: search for modifiable and unmodifiable risk factors affecting the quality of life of patients after rectal cancer surgery.Materials and methods: the literature search was done according to the keywords: quality of life, rectal cancer, low anterior resection syndrome. Twelve prospective randomized studies, 2 cohort studies, and 2 meta-analyses are included in the study. The quality of life was assessed in the analyzed studies by using questionnaires for cancer patients and updated questionnaires for colorectal cancer: EORTC QLQ-CR29, QLQ-C30, QLQ-CR38, BIQ.Results: the literary data on influence of gender, age, surgery, stoma, and chemoradiotherapy on life quality of patients after rectal cancer surgery was analyzed.Conclusion: the most significant factor affecting the life quality of patients with rectal cancer is a violation of the body image if it is necessary to form the stoma on the anterior abdominal wall. The manifestations of the low anterior resection syndrome and the urination problems are significant risk factors in the case of restoration of bowel continuity.

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Quality of life in rectal cancer surgery: What do the patient ask?

World Journal of Gastrointestinal Surgery ◽

10.4240/wjgs.v7.i12.349 ◽

2015 ◽

Vol 7 (12) ◽

pp. 349 ◽

Cited By ~ 6

Author(s):

Giovanni D De Palma

Keyword(s):

Quality Of Life ◽

Rectal Cancer ◽

Cancer Surgery ◽

Rectal Cancer Surgery

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Survival and Quality of Life of Patients After Rectal Cancer Surgery in a Low-Income Country: A Study in Cameroon, Sub-Saharan African Region

SSRN Electronic Journal ◽

10.2139/ssrn.3824691 ◽

2021 ◽

Author(s):

Guy Aristide Bang ◽

Eric Patrick Savom ◽

Georges Bwelles ◽

Julienne Yambassa Fayam ◽

Yannick Mahamat Ekani Boukar ◽

...

Keyword(s):

Quality Of Life ◽

Rectal Cancer ◽

Low Income ◽

Cancer Surgery ◽

Income Country ◽

Rectal Cancer Surgery ◽

African Region ◽

Low Income Country ◽

Sub Saharan

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Multicenter Prospective Cohort Study of the Patient-Reported Outcome Measures PRO-CTCAE and CAT EORTC QLQ-C30 in Major Abdominal Cancer Surgery (PATRONUS): A Student-Initiated German Medical Audit (SIGMA) Study

Annals of Surgical Oncology ◽

10.1245/s10434-021-09646-z ◽

2021 ◽

Author(s):

André L. Mihaljevic ◽

Keyword(s):

Quality Of Life ◽

Postoperative Complications ◽

Computerized Adaptive Testing ◽

Cancer Surgery ◽

Life Questionnaire ◽

Cancer Symptoms ◽

Patient Reported ◽

Eortc Qlq C30 ◽

Eortc Qlq

Abstract Background The patient-reported outcomes (PRO) version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) and the computerized adaptive testing (CAT) version of the EORTC quality-of-life questionnaire QLQ-C30 have been proposed as new PRO measures in oncology; however, their implementation in patients undergoing cancer surgery has not yet been evaluated. Methods Patients undergoing elective abdominal cancer surgery were enrolled in a prospective multicenter study, and postoperative complications were recorded according to the Dindo–Clavien classification. Patients reported PRO data using the CAT EORTC QLQ-C30 and the PRO-CTCAE to measure 12 core cancer symptoms. Patients were followed-up for 6 months postoperatively. The study was carried out by medical students of the CHIR-Net SIGMA study network. Results Data of 303 patients were obtained and analyzed across 15 sites. PRO-CTCAE symptoms ‘poor appetite’, ‘fatigue’, ‘exhaustion’ and ‘sleeping problems’ increased after surgery and climaxed 10–30 days postoperatively. At 3–6 months postoperatively, no PRO-CTCAE symptom differed significantly to baseline. Patients reported higher ‘social functioning’ (p = 0.021) and overall quality-of-life scores (p < 0.05) 6 months after cancer surgery compared with the baseline level. There was a lack of correlation between postoperative complications or death and any of the PRO items evaluated. Feasibility endpoints for student-led research were met. Conclusion The two novel PRO questionnaires were successfully applied in surgical oncology. Postoperative complications do not affect health-reported quality-of-life or common cancer symptoms following major cancer surgery. The feasibility of student-led multicenter clinical research was demonstrated, but might be enhanced by improved student training.

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TENS effects on dysesthesia and quality of life after breast cancer surgery with axilectomy: randomized controlled trial

Fisioterapia em Movimento ◽

10.1590/1980-5918.030.s01.ao28 ◽

2017 ◽

Vol 30 (suppl 1) ◽

pp. 285-295

Author(s):

Andreza Carvalho Rabelo Mendonça ◽

Mariana Tirolli Rett ◽

Priscila de Araújo Garcez ◽

Maria Jane das Virgens Aquino ◽

Lucas Vasconcelos Lima ◽

...

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Cancer Surgery ◽

Breast Cancer Surgery ◽

Controlled Clinical Trial ◽

Axillary Lymphadenectomy ◽

Eortc Qlq C30 ◽

Intercostobrachial Nerve ◽

Eortc Qlq

Abstract Introduction: After breast cancer surgery, many women may present quality of life (QOL) impairment due to the presence of discomfort as dysesthesia in the anterolateral region of the chest, armpit and/or medial part of the arm caused by intercostobrachial nerve injury (ICBN). Objective: To investigate the effects of Transcutaneous Electrical Nerve Stimulation (TENS) on dysesthesia intensity at the intercostobrachial nerve (ICBN) dermatome and QOL in women after breast cancer surgery. Methods: A randomized, double-blinded, placebo controlled clinical trial was conducted. Women undergoing axillary lymphadenectomy (AL), with dysesthesia on ICBN dermatome were included. Patients were divided into active and placebo TENS groups. TENS was applied with a frequency of 100 Hz, pulse duration of 100 µs and amplitude at the highest sensory intensity tolerable for 20 minutes during 20 sessions, three times a week, on alternating days. In the placebo TENS group, electrical current was delivered only during the first 45 seconds of application. Skin sensitivity was assessed by esthesiometry. Dysesthesia intensity was assessed with a visual analogue scale (VAS) and QOL with the EORTC QLQ-C30 and the specific EORTC QLQ-BR23 which is the Breast Cancer Module. Results: VAS decreased significantly over the 20 sessions in the active TENS group (p<0.006) and no difference was found between groups. There weren’t significant differences in EORTC QLQ-C30 and EORTC QLQ-BR23 after 20 sessions or between groups. Conclusion: TENS decreased dysesthesia intensity in the ICBN dermatome after breast cancer surgery, but did not improve quality of life.

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