Role of diets and exercise in ameliorating obesity-related hepatic steatosis: Insights at the microRNA-dependent thyroid hormone synthesis and action

Life Sciences ◽  
2020 ◽  
Vol 242 ◽  
pp. 117182 ◽  
Author(s):  
Shu-Fang Xia ◽  
Yu-Yu Jiang ◽  
Yu-Yu Qiu ◽  
Wei Huang ◽  
Jun Wang
2005 ◽  
Vol 118 (2) ◽  
pp. 239-245 ◽  
Author(s):  
Alain VIRION ◽  
Danièale DEME ◽  
Jacques POMMIER ◽  
Jacques NUNEZ

1972 ◽  
Vol 69 (2) ◽  
pp. 321-328
Author(s):  
K. Liewendahl ◽  
E. Niskanen ◽  
A. Gordin

ABSTRACT The effects of excess iodide on the histology and function of the thyroid were studied in rats. A slight increase in thyroid weight and minimal histological alterations were observed. The thyroid function of rats was studied by measuring the serum total and free thyroxine. Excess iodide did not significantly change the concentration of thyroid hormone in the serum and signs of hypothyroidism were not seen. Thus, rats were capable of adaptation to chronic administration of large amounts of iodide. A slight increase in the serum thyrotrophin after prolonged ingestion of excess iodide was measured with both bioassay and radioimmunoassay techniques. The possible role of thyrotrophin in the mechanism of escape from the transient inhibition of iodide on thyroid hormone synthesis is discussed.


2005 ◽  
Vol 124 (3) ◽  
pp. 603-609 ◽  
Author(s):  
Françoise COURTIN ◽  
Danielle DEME ◽  
Alain VIRION ◽  
Jean Luc MICHOT ◽  
Jacques POMMIER ◽  
...  

1967 ◽  
Vol 55 (2) ◽  
pp. 361-368 ◽  
Author(s):  
R. McG. Harden ◽  
W. D. Alexander ◽  
S. Papadopoulos ◽  
M. T. Harrison ◽  
S. Macfarlane

ABSTRACT Iodine metabolism and thyroid function were studied in a patient with hypothyroidism and goitre due to dehalogenase deficiency. Initially the plasma inorganic iodine (PII) level was within the normal range but circulating levels of hormone were low and the thyroid clearance and absolute uptake of iodine (AIU) by the thyroid were high. Administration of iodide supplements resulted in a rapid rise in the plasma thyroxine concentration and restoration of the euthyroid state. Thyroid hormone synthesis appeared to proceed normally when the PII exceeded 1.0 μg/100 ml. This was achieved by increasing the intake of iodide by 612 μg per day. At PII levels around 10 μg/100 ml there was evidence of increased levels of circulating thyroid hormone.


1963 ◽  
Vol 19 (2) ◽  
pp. 103-104 ◽  
Author(s):  
Vera Dolgova ◽  
N. Serafimow ◽  
G. Sestakov

1980 ◽  
Vol 112 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Alain VIRION ◽  
Daniele DEME ◽  
Jacques POMMIER ◽  
Jacques NUNEZ

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