4-Phenylselanyl-7-chloroquinoline attenuates hepatic injury triggered by neonatal exposure to monosodium glutamate in rats

Life Sciences ◽  
2021 ◽  
pp. 119751
Author(s):  
Karline da Costa Rodrigues ◽  
Cristiani Folharini Bortolatto ◽  
Renata Leivas de Oliveira ◽  
Jaini Janke Paltian ◽  
Allya Muhammad Eid Larroza ◽  
...  
2012 ◽  
Vol 9 (1) ◽  
pp. 58 ◽  
Author(s):  
Kate S Collison ◽  
Nadine J Makhoul ◽  
Marya Z Zaidi ◽  
Rana Al-Rabiah ◽  
Angela Inglis ◽  
...  

2005 ◽  
Vol 82 (2) ◽  
pp. 247-251 ◽  
Author(s):  
E. Olvera-Cortés ◽  
M.A. López-Vázquez ◽  
C. Beas-Zárate ◽  
I. González-Burgos

2017 ◽  
Vol 76 (4) ◽  
pp. 582-589 ◽  
Author(s):  
L. Foran ◽  
C. Kupelian ◽  
S. Laroia ◽  
J. Esper ◽  
R. J. Kulesza

2016 ◽  
Vol 97 (1) ◽  
pp. 18-26 ◽  
Author(s):  
Julio César Rojas-Castañeda ◽  
Rosa María Vigueras-Villaseñor ◽  
Margarita Chávez-Saldaña ◽  
Patricia Rojas ◽  
Oscar Gutiérrez-Pérez ◽  
...  

2019 ◽  
Vol 21 (2) ◽  
pp. 134-141
Author(s):  
Tapati Bhattacharya ◽  
S.K. Ghosh

 Monosodium Glutamate (MSG) is a commonly used food additive. Scientists have found that MSG has toxic effects in several tissues and organs like neurons, liver, testes, ovary, kidneys etc due to oxidative stress both after exposure in neonatal period as well as in adult animal models. Although various reports have suggested that MSG has damaging effect in kidneys only few histological studies are available. This study was done to observe any histological changes in kidneys of albino mice after neonatal exposure with MSG. Study showed significant changes in weight and volume of kidneys in gross morphology. Increased urinary space and dilatation of proximal convoluted tubules (PCT) and distal convoluted tubules (DCT) were constant finding in experimental animals. There were loss of luminal microvilli and reduced height of lining cells of both PCT and DCT.


Author(s):  
Nalin J. Unakar

The increased number of lysosomes as well as the close approximation of lysosomes to the Golgi apparatus in tissue under variety of experimental conditions is commonly observed. These observations suggest Golgi involvement in lysosomal production. The role of the Golgi apparatus in the production of lysosomes in mouse liver was studied by electron microscopy of liver following toxic injury by CCI4.


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