Vessel wall characteristics using high-resolution magnetic resonance imaging in reversible cerebral vasoconstriction syndrome and central nervous system vasculitis

2013 ◽  
Vol 42 (4) ◽  
pp. 692 ◽  
Author(s):  
R. Cerejo ◽  
T. Hammad ◽  
E. Obusez ◽  
S. John ◽  
K. Uchino ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Central Nervous System ◽  
Nervous System ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Vessel Wall ◽  
Reversible Cerebral Vasoconstriction Syndrome ◽  
Resonance Imaging ◽  
Central Nervous System Vasculitis ◽  
Cerebral Vasoconstriction

scholarly journals Vessel Wall MRI to Differentiate Between Reversible Cerebral Vasoconstriction Syndrome and Central Nervous System Vasculitis

Stroke ◽  
2012 ◽  
Vol 43 (3) ◽  
pp. 860-862 ◽  
Author(s):  
Daniel M. Mandell ◽  
Charles C. Matouk ◽  
Richard I. Farb ◽  
Timo Krings ◽  
Ronit Agid ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Vessel Wall ◽  
Reversible Cerebral Vasoconstriction Syndrome ◽  
Central Nervous System Vasculitis ◽  
Cerebral Vasoconstriction

scholarly journals Magnetic resonance imaging in central nervous system vasculitis in a patient affected by crioglobulin-negative hepatitis C virus infection: A likely correlation

2017 ◽  
Vol 31 (2) ◽  
pp. 193-195
Author(s):  
Silvia Squarza ◽  
Alberto Galli ◽  
Maurizio Cariati ◽  
Federico Alberici ◽  
Valentina Bertolini ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Central Nervous System ◽  
Nervous System ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Magnetic Resonance ◽  
Brain Lesion ◽  
Brain Biopsy ◽  
Resonance Imaging ◽  
Central Nervous System Vasculitis

A 56-year-old man with behavioural disorders and facial-brachio-crural right hemiparesis presented with a brain lesion studied with computed tomography, magnetic resonance imaging and brain biopsy, leading to the diagnosis of cerebral vasculitis. Hepatitis C virus (HCV) infection in a phase of activity, without cryoglobulins, was also detected. Brain biopsy, laboratory analysis and response to a specific therapy supported the diagnosis of central nervous system vasculitis that was HCV related.

scholarly journals Large and Small Cerebral Vessel Involvement in Severe COVID-19

Stroke ◽  
2020 ◽  
Vol 51 (12) ◽  
pp. 3719-3722 ◽  
Author(s):  
Emanuela Keller ◽  
Giovanna Brandi ◽  
Sebastian Winklhofer ◽  
Lukas L. Imbach ◽  
Daniel Kirschenbaum ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Central Nervous System ◽  
Cerebrospinal Fluid ◽  
Nervous System ◽  
Ischemic Stroke ◽  
Magnetic Resonance ◽  
Vessel Wall ◽  
Cerebrovascular Disorders ◽  
Central Nervous System Involvement ◽  
Resonance Imaging

Background and Purpose: Case series indicating cerebrovascular disorders in coronavirus disease 2019 (COVID-19) have been published. Comprehensive workups, including clinical characteristics, laboratory, electroencephalography, neuroimaging, and cerebrospinal fluid findings, are needed to understand the mechanisms. Methods: We evaluated 32 consecutive critically ill patients with COVID-19 treated at a tertiary care center from March 9 to April 3, 2020, for concomitant severe central nervous system involvement. Patients identified underwent computed tomography, magnetic resonance imaging, electroencephalography, cerebrospinal fluid analysis, and autopsy in case of death. Results: Of 32 critically ill patients with COVID-19, 8 (25%) had severe central nervous system involvement. Two presented with lacunar ischemic stroke in the early phase and 6 with prolonged impaired consciousness after termination of analgosedation. In all but one with delayed wake-up, neuroimaging or autopsy showed multiple cerebral microbleeds, in 3 with additional subarachnoid hemorrhage and in 2 with additional small ischemic lesions. In 3 patients, intracranial vessel wall sequence magnetic resonance imaging was performed for the first time to our knowledge. All showed contrast enhancement of vessel walls in large cerebral arteries, suggesting vascular wall pathologies with an inflammatory component. Reverse transcription-polymerase chain reactions for SARS-CoV-2 in cerebrospinal fluid were all negative. No intrathecal SARS-CoV-2-specific IgG synthesis was detectable. Conclusions: Different mechanisms of cerebrovascular disorders might be involved in COVID-19. Acute ischemic stroke might occur early. In a later phase, microinfarctions and vessel wall contrast enhancement occur, indicating small and large cerebral vessels involvement. Central nervous system disorders associated with COVID-19 may lead to long-term disabilities. Mechanisms should be urgently investigated to develop neuroprotective strategies.

Sign in / Sign up

Export Citation Format

Share Document