A detailed paleoceanographic history of the Subantarctic region for the last million years was determined using paleomagnetic stratigraphy, radiolarian and planktonic foraminiferal biostratigraphy, and the oxygen isotope record from stages 1 to 13 (0.5 MY) in a deep-sea core (E45-74) from the southern Indian Ocean. Changes in the abundances of Antarctissa strelkovi and Neogloboquadrina pachyderma record 12 glacial/interglacial cycles. The paleoceanographic events based on the combined results of these siliceous and calcareous indexes agree with changes in the global ice-volume record. Calcium carbonate dissolution selectively alters the planktonic foraminiferal fauna and causes test fragmentation and increased numbers of benthic foraminifera and radiolarians. Intense periods of calcium carbonate dissolution are associated principally with glacial episodes and are probably related to increased Antarctic bottom-water activity as well as changes in surface-water mass positions.