Non-cytotoxic and non-genotoxic wear debris of strontium oxide doped (Zirconia Toughened Alumina) (SrO-ZTA) implant for hip prosthesis

2021 ◽  
Vol 274 ◽  
pp. 125187
Author(s):  
Nibedita Nayak ◽  
Shaik Akbar Basha ◽  
Surya Kant Tripathi ◽  
Bijesh K. Biswal ◽  
Monalisa Mishra ◽  
...  
2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Tim W. Rattay ◽  
Torsten Kluba ◽  
Ludger Schöls

AbstractA 53-year old male with a history of progressive visual impairment, hearing loss, peripheral neuropathy, poorly controlled diabetes mellitus, cardiomyopathy, and weight loss was referred to the rare disease center due to the suspicion of mitochondrial cytopathy. In line with mitochondrial dysfunction, lactate in CSF was increased. Genetic testing by whole-exome sequencing and mitochondrial DNA did not reveal a likely cause. The case remained unsolved until he developed pain in his right hip, where he had received total hip arthroplasty 12 years earlier. An orthopedic evaluation revealed substantial shrinkage of the head of the hip prosthesis. Due to metal-on-metal wear, debris chromium and cobalt levels in serum were massively increased and significantly improved with multisystemic impairment after exchanging the defective implant.


2020 ◽  
Author(s):  
D. CHAPPARD ◽  
L. RONY ◽  
F. DUCELLIER ◽  
V. STEIGER ◽  
L. HUBERT

1998 ◽  
Vol 119 (1) ◽  
pp. 89-93 ◽  
Author(s):  
M.J. Day ◽  
S.J. Butterworth ◽  
M.R. Palmer ◽  
C.P. Case

1999 ◽  
Author(s):  
Donna M. Meyer ◽  
John A. Tichy

Abstract The development of the hip prosthesis is a result of extensive collaboration between the medical and engineering fields. Although the technology to replace ailing human joints with artificial replicas is quite advanced, these remarkable advances require additional attention. In particular, extending the service life of a hip prosthesis is a primary consideration. An artificial hip joint may require revision surgery due to a number of contributions, one of which is extensive wear. Within the first few years following hip implantation, high amounts of wear particles form due to the contact of the articulating surfaces. The amounts of wear debris generated is a function of the material combinations of the rubbing surfaces of the joint, the amount of lubrication present in the joint during activity and the types and levels of activity.


Bone ◽  
2012 ◽  
Vol 50 ◽  
pp. S188
Author(s):  
D. De Pasquale⁎ ◽  
A. Beraudi ◽  
M. Montesi ◽  
S. Squarzoni ◽  
F. Traina ◽  
...  

1999 ◽  
Vol 70 (6) ◽  
pp. 578-582 ◽  
Author(s):  
H Lucas Anissian ◽  
André Stark ◽  
Allen Gustafson ◽  
Victoria Good ◽  
Ian C Clarke

Bone ◽  
2009 ◽  
Vol 44 ◽  
pp. S289 ◽  
Author(s):  
S. Stea ◽  
F. Traina ◽  
A. Beraudi ◽  
M. Montesi ◽  
S. Squarzoni ◽  
...  

2006 ◽  
Vol 128 (10) ◽  
pp. 28-32 ◽  
Author(s):  
Alan S. Brown

This paper focuses on the development of modern metal-on-metal hips implants. Their large bearings mimic natural biomechanics and let patients remain active. Metal rubbing on metal creates nanoscale wear debris. The particles appear small enough for some cobalt and chrome to end up as ions. Both metals have the potential to cause cancer. Device manufacturers are scrambling after alloys that leave behind less debris. Some have also introduced ceramic hips. Ceramics are highly biocompatible and so hard and wear-resistant that they are likely to outlast metal. The ceramics used in hip implants are a triumph of materials science. The industry is moving toward zirconia-toughened alumina. It is stronger than conventional alumina and designers can slim down cup liners and use larger ceramic femoral bearings.


Author(s):  
S. Shankar ◽  
R. Nithyaprakash ◽  
R. Naveen Kumar ◽  
R. Aravinthan ◽  
Alokesh Pramanik ◽  
...  

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