Anticoagulation as a confounding factor in the diagnosis of acquired hemophilia

2021 ◽  
Author(s):  
Rocío Cabra Rodríguez ◽  
María José Ruíz Márquez
Keyword(s):  
Confounding Factor ◽  
Acquired Hemophilia

Items’ Cross-Category Associations as a Confounding Factor in the Implicit Association Test

2001 ◽  
Vol 48 (2) ◽  
pp. 123-134 ◽  
Author(s):  
Melanie C. Steffens ◽  
Inga Plewe
Keyword(s):  
Implicit Association Test ◽  
Confounding Factor ◽  
Reaction Times ◽  
Association Test ◽  
The Other ◽  
Reaction Time Difference ◽  
Implicit Association ◽  
Male And Female ◽  
Research Activities ◽  
Degree Of Association

Abstract. The introduction of the Implicit Association Test (IAT; Greenwald, McGhee, & Schwartz, 1998 ) has stimulated numerous research activities. The IAT is supposed to measure the degree of association between concepts. Instances have to be assigned to these concepts by pressing appropriate keys as quickly as possible. The reaction time difference between certain conditions, termed the IAT effect, is used as an indicator of the degree of the concepts’ association. We tested the hypothesis that the degree of association between one concept (or category) and the instances of the other presented concept also influences reaction times. In our experiment, the instances in the target categories, male and female names, were kept constant. The adjectives in the evaluative categories were manipulated: Either the pleasant adjectives were female-associated and the unpleasant adjectives were male-associated, or vice versa. These stereotypic associations were indeed found to exert a substantial influence on the size of the IAT effect. This finding casts doubt on the assumption that the IAT effect may be interpreted as a pure measure of the degree of association between concepts.

Pemphigus Vulgaris Associated with Acquired Hemophilia due to Factor VIII Inhibitor

2003 ◽  
Vol 65 (3) ◽  
pp. 223-226 ◽  
Author(s):  
Masahide YAMAGUCHI ◽  
Mamoru KOHDA ◽  
Hiroaki UEKI ◽  
Wataru FUJIMOTO
Keyword(s):  
Factor Viii ◽  
Pemphigus Vulgaris ◽  
Factor Viii Inhibitor ◽  
Acquired Hemophilia ◽  
Viii Inhibitor

Acquired Hemophilia: An Overview on Diagnosis and Treatment

2009 ◽  
Vol 2 (2) ◽  
pp. 29-32 ◽  
Author(s):  
Antonio Coppola ◽  
Mirko Di Capua ◽  
Matteo Nicola Dario Di Minno ◽  
Anna Maria Cerbone
Keyword(s):  
Diagnosis And Treatment ◽  
Acquired Hemophilia

scholarly journals Immunoadsorption for the Treatment of Acquired Hemophilia: New Observational Data, Systematic Review, and Meta-Analysis

2021 ◽  
Author(s):  
Michael Esteves Pereira ◽  
Christoph Bocksrucker ◽  
Johanna Anna Kremer Hovinga ◽  
Martin Mueller ◽  
Michael Daskalakis ◽  
...  
Keyword(s):  
Systematic Review ◽  
Observational Data ◽  
Meta Analysis ◽  
Acquired Hemophilia

scholarly journals Successful Management of Acquired Hemophilia A Associated with Bullous Pemphigoid: A Case Report and Review of the Literature

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Quentin Binet ◽  
Catherine Lambert ◽  
Laurine Sacré ◽  
Stéphane Eeckhoudt ◽  
Cedric Hermans
Keyword(s):  
Bullous Pemphigoid ◽  
Neutralizing Antibodies ◽  
Hemophilia A ◽  
Rare Condition ◽  
Term Treatment ◽  
Acquired Hemophilia A ◽  
Acquired Hemophilia ◽  
Short Term Treatment ◽  
Life Threatening ◽  
Dose Levels

Background. Acquired hemophilia A (AHA) is a rare condition, due to the spontaneous formation of neutralizing antibodies against endogenous factor VIII. About half the cases are associated with pregnancy, postpartum, autoimmune diseases, malignancies, or adverse drug reactions. Symptoms include severe and unexpected bleeding that may prove life-threatening.Case Study. We report a case of AHA associated with bullous pemphigoid (BP), a chronic, autoimmune, subepidermal, blistering skin disease. To our knowledge, this is the 25th documented case of such an association. Following treatment for less than 3 months consisting of methylprednisolone at decreasing dose levels along with four courses of rituximab (monoclonal antibody directed against the CD20 protein), AHA was completely cured and BP well-controlled.Conclusions. This report illustrates a rare association of AHA and BP, supporting the possibility of eradicating the inhibitor with a well-conducted short-term treatment.

Treatment of congenital and acquired hemophilia patients by extracorporeal removal of antibodies to coagulation factors: A review of US clinical studies 1987–1990

1992 ◽  
Vol 13 (2) ◽  
pp. 233-253 ◽  
Author(s):  
Robert M Watt ◽  
Kimberly Bunitsky ◽  
Elizabeth B Faulkner ◽  
Candace M Hart ◽  
Jennifer Horan ◽  
...  
Keyword(s):  
Clinical Studies ◽  
Coagulation Factors ◽  
Acquired Hemophilia ◽  
Extracorporeal Removal
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