Effects of aerobic exercise on fibroblast growth factor 21 in overweight and obesity. A systematic review

Metabolism ◽  
2022 ◽  
pp. 155137
Author(s):  
María Porflitt-Rodríguez ◽  
Valentina Guzmán-Arriagada ◽  
Romina Sandoval-Valderrama ◽  
Charmaine S. Tam ◽  
Francisca Pavicic ◽  
...  
Keyword(s):  
Systematic Review ◽  
Growth Factor ◽  
Aerobic Exercise ◽  
Fibroblast Growth Factor ◽  
Overweight And Obesity ◽  
Fibroblast Growth Factor 21 ◽  
Fibroblast Growth

Fibroblast Growth Factor 21 Expression and Insulin Resistance to Acute Aerobic Exercise in Obese Individuals

2015 ◽  
Vol 47 ◽  
pp. 236
Author(s):  
Arun Maharaj ◽  
Aaron L. Slusher ◽  
Michael Whitehurst ◽  
Robert F. Zoeller ◽  
James T. Mock ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Growth Factor ◽  
Aerobic Exercise ◽  
Fibroblast Growth Factor ◽  
Fibroblast Growth Factor 21 ◽  
Fibroblast Growth

scholarly journals Fibroblast growth factor 21, adiposity, and macronutrient balance in a healthy, pregnant population with overweight and obesity

2018 ◽  
Vol 43 (4) ◽  
pp. 275-283 ◽  
Author(s):  
Elizabeth F. Sutton ◽  
Christopher D. Morrison ◽  
Jacqueline M. Stephens ◽  
Leanne M. Redman
Keyword(s):  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Overweight And Obesity ◽  
Fibroblast Growth Factor 21 ◽  
Fibroblast Growth

Attenuated fibroblast growth factor 21 response to acute aerobic exercise in obese individuals

2015 ◽  
Vol 25 (9) ◽  
pp. 839-845 ◽  
Author(s):  
A.L. Slusher ◽  
M. Whitehurst ◽  
R.F. Zoeller ◽  
J.T. Mock ◽  
M. Maharaj ◽  
...  
Keyword(s):  
Growth Factor ◽  
Aerobic Exercise ◽  
Fibroblast Growth Factor ◽  
Fibroblast Growth Factor 21 ◽  
Fibroblast Growth

scholarly journals High-Level Serum Fibroblast Growth Factor 21 Concentration Is Closely Associated With an Increased Risk of Cardiovascular Diseases: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 8 ◽  
Author(s):  
Yucong Zhang ◽  
Jinhua Yan ◽  
Ni Yang ◽  
Zonghao Qian ◽  
Hao Nie ◽  
...  
Keyword(s):  
Systematic Review ◽  
Blood Pressure ◽  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Meta Analysis ◽  
Fibroblast Growth Factor 21 ◽  
Fibroblast Growth ◽  
Cvd Risk ◽  
Increased Risk ◽  
High Level

Background: The association between fibroblast growth factor 21 (FGF21) and cardiovascular disease (CVD) risk remains unclear. We conducted this systematic review and meta-analysis to evaluate the association between FGF21 and CVDs, and relevant vascular parameters.Methods: PubMed and Web of Science databases were systematically searched to identify relevant studies published before March 2021. The FGF21 concentration was compared between individuals with and without CVDs. The effect of FGF21 on CVD risk was assessed by using hazard ratio (HR) and odds ratio (OR). The association between FGF21 and vascular parameters was assessed by Pearson's r. Study quality was assessed using Newcastle–Ottawa Scale and Joanna Briggs Institution Checklist.Results: A total of 29,156 individuals from 30 studies were included. Overall, the serum FGF21 concentration was significantly higher in CVD patients (p < 0.001), especially for coronary artery disease (CAD) (p < 0.001) and hypertension (p < 0.001). The pooled OR (p = 0.009) and HR (p < 0.001) showed that the risk of CVDs increased with FGF21. The linear association between FGF21 and vascular parameters, including pulse wave velocity (r = 0.32), carotid intima-media thickness (r = 0.21), ankle-brachial index (r = 0.33), systolic blood pressure (r = 0.13), and diastolic blood pressure (r = 0.05), was insignificant. The incidence of overall CVDs (p = 0.03) was significantly higher in individuals with higher FGF21 levels.Conclusion: High-level serum FGF21 concentration is closely associated with an increased risk of CVDs, which may be independent of vascular parameters. A standard FGF21 classification threshold needs to be established before clinical use for CVD risk assessment.Systematic Review Registration:https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=241968, identifier: CRD42021241968.

Fibroblast growth factor 21 in cardio-metabolic disorders: a systematic review and meta-analysis

Metabolism ◽  
2018 ◽  
Vol 83 ◽  
pp. 11-17 ◽  
Author(s):  
Ishan Lakhani ◽  
Mengqi Gong ◽  
Wing Tak Wong ◽  
George Bazoukis ◽  
Konstantinos Lampropoulos ◽  
...  
Keyword(s):  
Systematic Review ◽  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Metabolic Disorders ◽  
Meta Analysis ◽  
Fibroblast Growth Factor 21 ◽  
Fibroblast Growth

Fibroblast growth factor-21 predicts adverse outcome in community-acquired pneumonia

2018 ◽  
Author(s):  
Fahim Ebrahimi ◽  
Carole Wolffenbuttel ◽  
Claudine A Blum ◽  
Beat Muller ◽  
Philipp Schuetz ◽  
...  
Keyword(s):  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Adverse Outcome ◽  
Community Acquired Pneumonia ◽  
Fibroblast Growth Factor 21 ◽  
Fibroblast Growth

Effects of anti-inflammatory treatment on fibroblast growth factor-21 in obesity and metabolic syndrome

2019 ◽  
Author(s):  
Fahim Ebrahimi ◽  
Sandrine Urwyler ◽  
Matthias Betz ◽  
Emanuel Christ ◽  
Philipp Schuetz ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Fibroblast Growth Factor 21 ◽  
Fibroblast Growth ◽  
Anti Inflammatory

Fibroblast growth factor 21 (FGF21) in hyper- and hypothyroidism, association with metabolic disturbances

2020 ◽  
Author(s):  
Ewa Szczepańska ◽  
Małgorzata Gietka-Czernel ◽  
Piotr Glinicki ◽  
Helena Jastrzębska ◽  
Jadwiga Słowińska-Srzednicka ◽  
...  
Keyword(s):  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Fibroblast Growth Factor 21 ◽  
Fibroblast Growth ◽  
Metabolic Disturbances
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