The interferon response is involved in nervous necrosis virus acute and persistent infection in zebrafish infection model

2008 ◽  
Vol 45 (4) ◽  
pp. 1146-1152 ◽  
Author(s):  
Ming-Wei Lu ◽  
Yung-Mei Chao ◽  
Tz-Chun Guo ◽  
Nina Santi ◽  
Øystein Evensen ◽  
...  
Keyword(s):  
Persistent Infection ◽  
Interferon Response ◽  
Infection Model ◽  
Nervous Necrosis Virus ◽  
Necrosis Virus ◽  
Zebrafish Infection

Characterization of red-spotted grouper nervous necrosis virus isolated from ovarian fluids of asymptomatic wild Asian seabass, Lates calcarifer

Aquaculture ◽  
2021 ◽  
pp. 736846
Author(s):  
Venkata Satyanarayana Nallala ◽  
M. Makesh ◽  
K. Radhika ◽  
T. Sathish Kumar ◽  
P. Raja ◽  
...  
Keyword(s):  
Nervous Necrosis Virus ◽  
Necrosis Virus ◽  
Lates Calcarifer ◽  
Asian Seabass

Grouper MAVS functions as a crucial antiviral molecule against nervous necrosis virus infection

2018 ◽  
Vol 72 ◽  
pp. 14-22 ◽  
Author(s):  
Youhua Huang ◽  
Jingcheng Zhang ◽  
Zhengliang Ouyang ◽  
Jiaxin Liu ◽  
Ya Zhang ◽  
...  
Keyword(s):  
Virus Infection ◽  
Nervous Necrosis Virus ◽  
Necrosis Virus

In vitro neutralization of nervous necrosis virus by a nanobody binding to the protrusion domain of capsid protein

Aquaculture ◽  
2021 ◽  
pp. 737654
Author(s):  
Song Zhu ◽  
Bo Miao ◽  
Yu-Zhou Zhang ◽  
Wei-Wei Zeng ◽  
De-Shou Wang ◽  
...  
Keyword(s):  
Capsid Protein ◽  
Nervous Necrosis Virus ◽  
Necrosis Virus

scholarly journals Mycobacterium marinum infection drives foam cell differentiation in zebrafish infection

2018 ◽  
Author(s):  
Matt D. Johansen ◽  
Joshua A. Kasparian ◽  
Elinor Hortle ◽  
Warwick J. Britton ◽  
Auriol C. Purdie ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Lipid Metabolism ◽  
Foam Cell ◽  
Mycobacterial Infection ◽  
Foam Cells ◽  
Mycobacterium Marinum ◽  
Infection Model ◽  
Structural Components ◽  
Important Target ◽  
Zebrafish Infection

AbstractHost lipid metabolism is an important target for subversion by pathogenic mycobacteria such as Mycobacterium tuberculosis. The appearance of foam cells within the granuloma are well-characterised effects of chronic tuberculosis. The zebrafish-Mycobacterium marinum infection model recapitulates many aspects of human-M. tuberculosis infection and is used as a model to investigate the structural components of the mycobacterial granuloma. Here, we demonstrate that the zebrafish-M. marinum granuloma contains foam cells and that the transdifferentiation of macrophages into foam cells is driven by the mycobacterial ESX1 pathogenicity locus. This report demonstrates conservation of an important aspect of mycobacterial infection across species.

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